Article
Chemistry, Applied
Maria Jesus Moran, Katia Martina, Vidmantas Bieliunas, Francesca Baricco, Silvia Tagliapietra, Gloria Berlier, Wim M. De Borggraeve, Giancarlo Cravotto
Summary: The use of copper(0) nanoparticles as a lead-free alternative catalyst for the hydrogenation of alkynes has shown promising results in producing high yields of (Z)-alkenes. The protocol relies on non-noble copper nanoparticles for reduction of various types of alkynes, with polyols acting as hydrogen sources. Enabling technologies like microwave and ultrasound irradiation can significantly decrease reaction time.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Emily A. Knott, Annie M. Zlevor, J. Louis Hinshaw, Paul F. Laeseke, Colin Longhurst, Jenifer Frank, Charles W. Bradley, Allison B. Couillard, Annika E. Rossebo, Zhen Xu, Fred T. Lee, Timothy J. Ziemlewicz
Summary: This study compared the acute and chronic safety and treatment effects of non-invasive hepatic histotripsy vs. percutaneous microwave ablation in a healthy porcine model. The results showed that histotripsy treatment had more spherical effects, fewer biliary complications, and greater treatment zone involution.
EUROPEAN RADIOLOGY
(2023)
Article
Food Science & Technology
Carlota Sanchez-Cordoba, Enrique Duran-Guerrero, Remedios Castro
Summary: This study investigated the effects of extraction techniques such as ultrasound or microwaves on the aroma of red wines. While pre-fermentative treatment with microwaves or ultrasound did not significantly modify the sensory profile, the application of these energies during the ageing phase showed positive trends. Ultrasound during ageing resulted in greater contribution of red fruits, aromatic intensity, and wood compared to microwaves, with Spanish oak chips providing more volatile compounds and less undesirable aromas than French oak, preferred for their aromatic intensity and wood descriptors.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Review
Chemistry, Physical
Claudia Carlucci
Summary: This article discusses the production of biodiesel using different catalytic methods, such as acids, bases, enzymes or supercritical fluids. Continuous flow processes and microreactors provide better control over experimental variables, increasing efficiency and safety. Additionally, combining other technologies such as microwave irradiation or ultrasounds allows for automation of the production process.
Article
Engineering, Environmental
Jiangyong Liu, Rongfei Ye, Jie Shi, Haiyang Wang, Lixia Wang, Panming Jian, Dan Wang
Summary: The study presents a novel approach for the preparation of a Cu nanoparticles embedded nitrogen-doped carbon catalyst using cushaw and Cu salt, which shows promising catalytic performance in the liquid-phase reduction of nitrobenzene. Experimental and computational findings indicate the strong interaction between Cu nanoparticles and carbon layer, facilitating the adsorption and activation of NB molecules.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Biotechnology & Applied Microbiology
Pooja Saini, Nandana Chakinala, Praveen K. Surolia, Anand Gupta Chakinala
Summary: This study focuses on the synthesis, characterization, and evaluation of metal oxide-doped clay composite for the sonocatalytic degradation of nitrobenzene. It was found that copper and iron oxide-modified clay performed better in the degradation of nitrobenzene compared to a zinc oxide/clay composite. Process optimization showed that neutral pH conditions and higher catalyst loadings were optimal for the efficient degradation of nitrobenzene. The catalyst was also found to be effective in the degradation of other pollutants. These findings contribute to the development of cost-effective strategies for the treatment of industrial effluents.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Physical
Lingqi Huang, Zhiyong Luo, Wenjie Han, Qi Zhang, He Zhu, Shiping Zhu
Summary: In this study, hollow porous carbons (HPCs) were prepared using a simple and cost-effective method, and their potential in catalysis was demonstrated through the fabrication of Au@HPCs yolk-shell composites.
Article
Materials Science, Multidisciplinary
Julian Lopez-Tinoco, Javier Lara-Romero, Ricardo Rangel, Jose Apolinar-Cortes, Francisco Paraguay-Delgado, Sergio Jimenez-Sandoval, Lourdes Bazan-Diaz, Ruben Mendoza-Cruz
Summary: Ceria nanoparticles supported on multiwalled carbon nanotubes were synthesized successfully and showed great potential in removing organic dyes from contaminated water. The composites exhibited higher dye adsorption capability and removal percentage compared to functionalized carbon nanotubes.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Acoustics
Rodrigo Araya-Hermosilla, Jessica Martinez, Cesar Zuniga Loyola, Sara Ramirez, Sebastian Salazar, Charles S. Henry, Roberto Lavin, Nataly Silva
Summary: This research focuses on the systematic synthesis of Ag, Cu, and Ag/Cu metallic nanoparticles (MNPs) on cellulose paper in situ using ultrasound assistance. By adjusting the concentration of AgNO3 and CuSO4 salt precursors, as well as the ultrasound time, along with a fixed concentration of ascorbic acid (AA) as a reducing agent, the size, morphology, and polydispersity of the resulting MNPs on cellulose papers can be controlled. The proposed method provides insights into the factors affecting the sonochemical in situ synthesis of MNPs on cellulose papers, and offers a straightforward and eco-friendly alternative for scaled-up production of MNPs on paper.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Chemistry, Applied
Zhi Long Ma, Jian Yun Shi, Meng Chen Wang, Li Tian
Summary: Ln-coordination polymer Tb(BTTA)(1.5)(H2O)(4.5)]n (Tb-1) was successfully synthesized, displaying two-dimensional frameworks with one-dimensional channels. Tb-1 showed high selectivity and sensitivity for Cu2+ and MnO4-, as well as high recognition ability and low detection limit for nitrobenzene.
Article
Chemistry, Multidisciplinary
Saddam Iraqui, Babul Kalita, Rei Star, Mukul Gupta, Md. Harunar Rashid
Summary: In this study, a green approach for synthesizing CuFe2O4 nanoparticles was explored using Lantana camara flower extract as a capping agent. The extract played a significant role in controlling the size and shape of the formed nanoparticles, resulting in different morphologies. These nanoparticles exhibited catalytic activity in Chan-Lam type C-N coupling reactions and could be easily recovered and reused with an external magnet.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Physics, Multidisciplinary
Swarnali Hait, Anupam Gorai, Kalyan Mandal
Summary: Barium and Yttrium co-doping at the Bi site of BiFeO3 nanoparticles was found to enhance the dielectric and magnetic properties of the sample, leading to improved microwave absorption performance.
Article
Biochemistry & Molecular Biology
Viktoria Hajdu, Gabor Muranszky, Miklos Nagy, Erika Kopcsik, Ferenc Kristaly, Bela Fiser, Bela Viskolcz, Laszlo Vanyorek
Summary: In this study, a magnetically separable palladium catalyst with high catalytic activity was developed for the hydrogenation of aniline. The catalyst demonstrated high conversion and selectivity, and could be reused for multiple cycles.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Chemistry, Applied
Manoj Kumar, Maharishi Tomar, Jayashree Potkule, Reetu Verma, Sneh Punia, Archana Mahapatra, Tarun Belwal, Anil Dahuja, Shourabh Joshi, Mukesh K. Berwal, Varsha Satankar, Anilkumar G. Bhoite, Ryszard Amarowicz, Charanjit Kaur, John F. Kennedy
Summary: The importance of plant proteins in nutrition is rising due to their health benefits and sustainability aspect. Effective utilization of bio and physical extraction technologies can enable efficient protein recovery while minimizing environmental pollution.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Multidisciplinary
Bo Wu, Tiejun Lin, Ruoou Yang, Min Huang, Huan Zhang, Ji Li, Fanfei Sun, Fei Song, Zheng Jiang, Liangshu Zhong, Yuhan Sun
Summary: The study shows that chemoselective hydrogenation of nitrobenzene to azoxybenzene can be achieved using Ru single atoms coordinated with oxygen atoms in CeO2, offering a selectivity of 88.2%. This work provides a new strategy for the development of an efficient and green catalytic route.
Article
Chemistry, Applied
Maria Jesus Moran, Katia Martina, Vidmantas Bieliunas, Francesca Baricco, Silvia Tagliapietra, Gloria Berlier, Wim M. De Borggraeve, Giancarlo Cravotto
Summary: The use of copper(0) nanoparticles as a lead-free alternative catalyst for the hydrogenation of alkynes has shown promising results in producing high yields of (Z)-alkenes. The protocol relies on non-noble copper nanoparticles for reduction of various types of alkynes, with polyols acting as hydrogen sources. Enabling technologies like microwave and ultrasound irradiation can significantly decrease reaction time.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Chemistry, Applied
Arianna Binello, Giancarlo Cravotto, Janet Menzio, Silvia Tagliapietra
Summary: PAHs, potentially genotoxic and carcinogenic compounds, are mainly derived from incomplete combustion and pyrolysis of organic matter. Coffee, a widely consumed beverage, may contain PAHs due to roasting processes. To ensure the safety of this popular commodity, control over the entire production chain is essential.
Review
Pharmacology & Pharmacy
Laszlo Jicsinszky, Katia Martina, Giancarlo Cravotto
Summary: The article summarizes the interactions between main antiviral drugs and cyclodextrin, as well as changes in the properties of antiviral agents. It points out the potential complexation of antiviral molecules against SARS-Cov2 and discusses the lack of information in designing drugs against viral infections. Additionally, it highlights the potential of cyclodextrin derivatives in improving solubility and bioavailability of antiviral molecules.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Organic
Katia Martina, Giancarlo Cravotto, Rajender S. Varma
Summary: Microwave-assisted organic synthesis has become a mature technology with numerous advantages in terms of reaction rate and yield, and it also helps in scaling up production.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Applied
Pengyun Liu, Zhilin Wu, Alessandro Barge, Luisa Boffa, Katia Martina, Giancarlo Cravotto
Summary: CPAC-SPE-HPLC has been developed for the determination of multiple antibiotics in water and milk, showing high recovery rates and sensitivity, making it suitable for the analysis of different samples.
Article
Infectious Diseases
Marziale Comito, Riccardo Monguzzi, Silvia Tagliapietra, Giovanni Palmisano, Giancarlo Cravotto
Summary: A new and efficient method for synthesizing cefonicid benzathine salt is reported, with good yield and high product stability. The double-nucleophilic nature of N',N''-dibenzylethylene diacetate allows for deformylation of the protected hydroxyl group and product crystallization to occur.
Review
Biochemistry & Molecular Biology
Marziale Comito, Riccardo Monguzzi, Silvia Tagliapietra, Giovanni Palmisano, Giancarlo Cravotto
Summary: Continuous-flow chemistry has become a mainstream process for drug synthesis, offering advantages in safety, speed, cost efficiency, and equipment footprint. It also meets the quality objectives of drug development protocols. Governments worldwide strongly encourage the study and implementation of this sustainable and environmentally friendly technology. This review evaluates the development and applications of continuous-flow processes for antibiotic synthesis from 2012 to 2022, providing an overview and starting point for understanding the impact of flow chemistry on antibiotic synthesis.
Article
Pharmacology & Pharmacy
Marziale Comito, Riccardo Monguzzi, Silvia Tagliapietra, Angelo Maspero, Giovanni Palmisano, Giancarlo Cravotto
Summary: Meropenem is the most commonly used carbapenem in clinical applications. The synthetic process of Meropenem involves a difficult and unsafe step of heterogeneous catalytic hydrogenation. Recent advancements in process chemistry have led to the investigation of using microwave-assisted flow chemistry as a new technology for Meropenem synthesis. By optimizing reaction parameters, a semi-continuous flow protocol was developed that halved the reaction time compared to batch production while maintaining the same product quality.
Article
Pharmacology & Pharmacy
Federica Foglietta, Annalisa Bozza, Chiara Ferraris, Luigi Cangemi, Valentina Bordano, Loredana Serpe, Katia Martina, Loretta Lazzarato, Stefania Pizzimenti, Margherita Grattarola, Marie Angele Cucci, Chiara Dianzani, Luigi Battaglia
Summary: Despite advancements in cancer genomic and immunotherapies, advanced melanoma remains a life-threatening disease. In order to improve targeted drug delivery to the tumor, injectable lipid nanoemulsions were functionalized with proteins using two different approaches: chemically grafting transferrin for active targeting, and wrapping cancer cell membrane fragments for homotypic targeting. Protein functionalization was successful in both cases. Preliminary studies using flow cytometry showed that cell-membrane-fragment-wrapped nanoemulsions had higher cell uptake compared to uncoated nanoemulsions. However, transferrin grafting had a less pronounced effect in serum-enriched medium, possibly due to competition with endogenous proteins. Moreover, a more significant internalization was achieved when a pegylated heterodimer was used for conjugation (p < 0.05).
Article
Food Science & Technology
Giulia Strocchi, Anja B. Mueller, Nikolai Kuhnert, Katia Martina, Carlo Bicchi, Erica Liberto
Summary: Diterpenes, important compounds in coffee, are affected by various factors. During storage, coffee can undergo chemical and physical reactions that lead to the degradation and oxidation of diterpenes. This study analyzes the impact of long-term storage on the diterpene content in different coffee blends and packaging, and finds that the permeability of packaging and blends affects the modification of diterpenes.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Chemistry, Multidisciplinary
Francesco Ferlin, Daniele Sciosci, Federica Valentini, Janet Menzio, Giancarlo Cravotto, Katia Martina, Luigi Vaccaro
Summary: This study presents a waste-minimized protocol for Sonogashira cross-coupling using a CPME/water azeotropic mixture and a heterogeneous hybrid palladium catalyst supported onto a silica/beta-cyclodextrin matrix. Key features include the crucial utilization of the aq CPME azeotrope, downstream liquid/liquid separation for continuous recovery and reuse of CPME fraction, and a comprehensive analysis highlighting the chemical and environmental efficiency of the protocol.
Article
Chemistry, Physical
Alessio Zuliani, Manuel Cano, Federica Calsolaro, Alain R. Puente Santiago, Juan J. Giner-Casares, Enrique Rodriguez-Castellon, Gloria Berlier, Giancarlo Cravotto, Katia Martina, Rafael Luque
Summary: The study introduces a novel environmentally friendly approach for developing stable and active catalysts for the oxygen evolution reaction, utilizing polyphenols and activated carbon derived from pinecones to prepare low cobalt loading composites. The use of ultrasound and microwave assisted techniques aimed at enhancing electrocatalytic activity, demonstrating that the best sample required an overpotential of 365mV to achieve a current density of 10mA/cm(-2) with a Tafel slope of 58mV/dec(-1).
SUSTAINABLE ENERGY & FUELS
(2021)