Article
Economics
Farzana Afridi, Sisir Debnath, E. Somanathan
Summary: The study in central India found that combining health awareness with information on a universal cash-back LPG subsidy program significantly increased the purchase and usage of clean fuels among villagers. The results highlight the importance of financial constraints and the design of public subsidy schemes in promoting regular usage of clean fuels.
JOURNAL OF DEVELOPMENT ECONOMICS
(2021)
Article
Sport Sciences
Mikael Flockhart, Lina C. Nilsson, Bjorn Ekblom, Filip J. Larsen
Summary: This study uses mitochondrial function as an early marker for excessive training loads and develops a diagnostic model based on dynamic responses of physiological and psychological measurements. The model successfully identifies the training loads that lead to maladaptations.
SPORTS MEDICINE-OPEN
(2022)
Review
Neurosciences
Ashleigh M. Philp, Nicholas J. Saner, Michael Lazarou, Ian G. Ganley, Andrew Philp
Summary: Mitochondria are dynamic organelles designed to meet cellular energy demands, exhibiting high plasticity in response to alterations in energy demand. Aerobic exercise is a potent stimulus for skeletal muscle remodelling, leading to changes in mitochondrial quality control. There is a rapidly advancing understanding of mitochondrial quality control in skeletal muscle and the regulatory role of aerobic exercise on this process.
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Editorial Material
Chemistry, Physical
Benjamin Martindale, Staff Sheehan
Summary: Staff Sheehan, a co-founder and Chief Technology Officer at Air Company, discusses how the startup uses heterogeneous catalysis to convert CO2 into valuable products. In the interview with Nature Catalysis, he shares insights on the company's innovation and the potential applications of chemical reactions in various fields.
Review
Nutrition & Dietetics
Jeronimo Aragon-Vela, Olivia Gonzalez-Acevedo, Julio Plaza-Diaz, Rafael A. Casuso, Jesus R. Huertas
Summary: This systematic review evaluates the efficacy of seawater consumption in long-duration sport events. The results indicate that consuming seawater can accelerate the recovery of aerobic capacity and muscle capacity, while reducing lactate production after running exercise.
Article
Multidisciplinary Sciences
Camilla W. Stjern, Oivind Hodnebrog, Gunnar Myhre, Ignacio Pisso
Summary: This study shows that emissions of CO2 and black carbon in the atmosphere affect the frequency of severe air pollution episodes by influencing turbulence and the height of the planetary boundary layer (PBL). While absorbing aerosols contribute to stability and reduced turbulence in the boundary layer through atmospheric heating, CO2 has the opposite effect through surface warming. In future scenarios with increased CO2 concentrations and reduced aerosol emissions, around 10% of the global population living in highly polluted regions are likely to experience increased turbulence and PBL height, leading to a reduction in intense pollution events.
NATURE COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Remigiusz Domin, Michal Pytka, Mikolaj Zolynski, Jan Nizinski, Marcin Rucinski, Przemyslaw Guzik, Jacek Zielinski, Marek Ruchala
Summary: This study aimed to investigate the relationship between serum MOTS-c concentration and muscle strength parameters, as well as oxygen consumption, in physically active individuals. The results showed that higher serum MOTS-c concentration was associated with greater muscle mass, force, and power, but not with exercise capacity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Editorial Material
Immunology
Federico F. De Ponti, Charlotte L. Scott
Summary: Hypoxia during acute respiratory distress syndrome alters populations of monocytes and macrophages, leading to persistent inflammation, which can be reversed by therapeutic administration of CSF1.
Review
Sport Sciences
Kellsey N. Smith, Tracy Baynard, Peter S. Fischbach, Jane S. Hankins, Lewis L. Hsu, Peggy M. Murphy, Kiri K. Ness, Shlomit Radom-Aizik, Amy Tang, Robert Liem
Summary: In total, 24 studies met inclusion/exclusion criteria. Adverse events were reported in 3.8% of 939 participants with SCD undergoing maximal CPET, with most related to transient ischaemic changes on ECG monitoring or oxygen desaturation during testing. Only 0.43% experienced pain events related to maximal CPET.
BRITISH JOURNAL OF SPORTS MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Dino A. Giussani
Summary: The article explores the impact of chronic fetal hypoxia during pregnancy on the development of cardiovascular disease in offspring and potential therapeutic approaches, with a focus on molecular-level research and potential targets for clinical intervention.
Review
Cell Biology
Han Dong, Shih-Yin Tsai
Summary: Mitochondria are crucial for energy production and play a vital role in various biological processes in eukaryotic cells. Skeletal muscle heavily relies on mitochondria for energy supplementation and also relies on them for maintaining calcium and reactive oxygen species levels. This review summarizes recent studies on mitochondria function and quality control in skeletal muscle, focusing on in vivo studies of rodents and human subjects. The interplay between mitochondrial functions and muscle fiber type-specific phenotypes, as well as the impact of aging and exercise on skeletal muscle and mitochondria properties, is also discussed.
Article
Neurosciences
Dean Minnock, Giosue Annibalini, Giacomo Valli, Roberta Saltarelli, Mauricio Krause, Elena Barbieri, Giuseppe De Vito
Summary: Growing evidence suggests that people with type 1 diabetes have impaired skeletal muscle health, but this condition is not well characterized. This study found that a combined resistance and aerobic training intervention improved muscle function in type 1 diabetes patients, but to a lesser extent compared to healthy controls.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Review
Medicine, Research & Experimental
Colin Harper, Venkatesh Gopalan, Jorming Goh
Summary: This review examines the cellular and molecular changes in skeletal muscle mitochondria during aging, particularly focusing on the efficiency of mitochondrial coupling and its impact on muscle function decline. It also discusses how different exercise modalities can potentially reverse these changes and delay the onset of sarcopenia. Additional concepts such as mitophagy and the implications of muscle fiber type changes with sarcopenia on mitochondrial function are also integrated in this review.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Review
Oncology
Ying Zhang, Jin-Soo Kim, Tian-Zhen Wang, Robert U. Newton, Daniel A. Galvao, Robert A. Gardiner, Michelle M. Hill, Dennis R. Taaffe
Summary: Exercise is increasingly being recognized as a valuable treatment strategy in managing prostate cancer by releasing extracellular vesicles that may influence disease outcomes, including suppressing tumor development.
FRONTIERS IN ONCOLOGY
(2021)
Article
Medicine, General & Internal
Chantal A. Pileggi, Denis P. Blondin, Breana G. Hooks, Gaganvir Parmar, Irina Alecu, David A. Patten, Alexanne Cuillerier, Conor O'Dwyer, A. Brianne Thrush, Morgan D. Fullerton, Steffany AL Bennett, Eric Doucet, Francois Haman, Miroslava Cuperlovic-Culf, Ruth McPherson, Robert R. M. Dent, Mary-Ellen Harper
Summary: This study examined the efficacy of exercise training on mitochondrial function in women with obesity who showed minimal weight loss in response to diet. The findings indicate that exercise intervention can improve body composition and skeletal muscle mitochondrial content in diet-resistant women. In-depth analyses of muscle metabolomes revealed distinct metabolic differences in response to exercise training.
Letter
Public, Environmental & Occupational Health
Johannes Burtscher, Gregoire P. Millet, Martin Burtscher
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2023)
Review
Cell Biology
Johannes Burtscher, Afsaneh Soltany, Nishant P. P. Visavadiya, Martin Burtscher, Gregoire P. Millet, Kayvan Khoramipour, Andy V. V. Khamoui
Summary: Mitokines are signaling molecules that enable communication of local mitochondrial stress to distant cells and tissues. They play a crucial role in mediating exercise-derived and dietary strategy-related health benefits, such as healthy aging. Maintaining balanced mitokine levels is important for inter-tissue cross talk and preventing age-related diseases. While low levels of mitokines impair inter-organ crosstalk, excessive concentrations can have deleterious consequences.
Review
Biochemistry & Molecular Biology
Robert T. Mallet, Johannes Burtscher, Vincent Pialoux, Qadar Pasha, Yasmin Ahmad, Gregoire P. Millet, Martin Burtscher
Summary: High-altitude illnesses result from acute exposure to high altitude/hypoxia. Understanding molecular mechanisms is essential for optimizing hypoxic acclimatization for efficient prophylaxis and treatment of these illnesses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Public, Environmental & Occupational Health
Johannes Burtscher, Erik R. Swenson, Peter Hackett, Gregoire P. Millet, Martin Burtscher
Summary: Background altitude sojourns attract individuals of all ages and different health statuses, but the risk of acute mountain sickness (AMS) when flying to high altitude destinations is often overlooked. This mini-review evaluates the altitude-dependent AMS incidence depending on the mode of ascending, such as air travel or terrestrial travel.
JOURNAL OF TRAVEL MEDICINE
(2023)
Article
Environmental Sciences
Johannes Burtscher, Gregoire P. P. Millet, Barbara Leitner, Martin Burtscher
Summary: Moderate altitude residence may be protective against cardiovascular diseases but may have higher mortality from certain respiratory diseases. The effects of altitude on COVID-19 mortality are still uncertain. This study analyzed a dataset from an Alpine country in Europe and found no differences in COVID-19 mortality between different altitude regions for the overall population and population older than 60, but a reduced mortality was observed among very old women (over 85 years old) at moderate altitudes.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Editorial Material
Hospitality, Leisure, Sport & Tourism
Johannes Burtscher, Barbara Strasser, Giuseppe D'Antona, Gregoire P. Millet, Martin Burtscher
JOURNAL OF SPORT AND HEALTH SCIENCE
(2023)
Letter
Anthropology
Johannes Burtscher, Hannes Gatterer, Gregoire P. Millet, Martin Burtscher
AMERICAN JOURNAL OF HUMAN BIOLOGY
(2023)
Editorial Material
Sport Sciences
Martin Burtscher, Martin Kopp, Gregoire P. Millet, Johannes Burtscher, Gerhard Ruedl
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Letter
Medicine, General & Internal
J. Burtscher, G. P. Millet, M. Burtscher
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
(2023)
Editorial Material
Physiology
Martin Burtscher, Johannes Burtscher
Editorial Material
Cardiac & Cardiovascular Systems
Martin Burtscher, Josef Niebauer
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Letter
Physiology
Tannheimer Markus, Johannes Burtscher, Martin Burtscher
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2023)
Article
Biophysics
Reinhard Puehringer, Martina Muckenthaler, Martin Burtscher
Summary: A study analyzed data from a large sample of male mountain guides and found that higher ferritin levels were weakly associated with lower cardiorespiratory fitness and a higher prevalence of cardiovascular risk factors.
HIGH ALTITUDE MEDICINE & BIOLOGY
(2023)
Article
Nutrition & Dietetics
Markus Schauer, Mohamad Motevalli, Derrick Tanous, Susanne Mair, Martin Burtscher, Katharina Wirnitzer, Carmina Wanden Berghe, Javier Sanz-Valero
Summary: This study investigated the association between physical activity level and micronutrient status among Austrian bank employees. The results showed a significant difference in overweight/obesity prevalence between different physical activity levels. However, there were no significant differences in sex, age, diet type, homocysteine, or CoQ10 markers. Most vitamins and minerals did not show a significant difference in blood concentrations based on physical activity levels.
Article
Biophysics
Zhaowei Kong, Qian Yu, Shengyan Sun, On Kei Lei, Yu Tian, Qingde Shi, Jinlei Nie, Martin Burtscher
Summary: The study found that sprint interval exercise had sustained executive benefits, and exercise in relatively severe hypoxia did not impair executive performance.
HIGH ALTITUDE MEDICINE & BIOLOGY
(2022)
Review
Physiology
Minyu Zhang, Biyang Xiao, Xiaoqi Chen, Bingming Ou, Songtao Wang
Summary: Non-alcoholic fatty liver disease (NAFLD) is closely related to bile acid and gut microbiota disorders. Exercise plays an important role in maintaining the homeostasis of the enterohepatic circulation and the health of the host gut microbiota by regulating the composition and function of the bile acid pool in the enterohepatic axis. Exercise has been recommended as a first-line intervention for NAFLD, and regulating bile acids through exercise may be a promising treatment strategy.