Enantioselective C–H functionalization of bicyclo[1.1.1]pentanes

Synthesis and applications of highly functionalized 1-halo-3-substituted bicyclo[1.1.1]pentanes

(2018) Dimitri F. J. Caputo et al.   Chemical Science

A General Amino Acid Synthesis Enabled by Innate Radical Cross-Coupling

(2018) Phil S. Baran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalyst-Controlled Selective Functionalization of Unactivated C–H Bonds in the Presence of Electronically Activated C–H Bonds

(2018) Wenbin Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design of catalysts for site-selective and enantioselective functionalization of non-activated primary C–H bonds

(2018) Kuangbiao Liao et al.   Nature Chemistry

Synthesis of BCP Benzylamines From 2-Azaallyl Anions and [1.1.1]Propellane

(2018) Russell A. Shelp et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonconjugated Hydrocarbons as Rigid-Linear Motifs: Isosteres for Material Sciences and Bioorganic and Medicinal Chemistry

(2018) Gemma M. Locke et al.   CHEMISTRY-A EUROPEAN JOURNAL

Branch-Selective Addition of Unactivated Olefins into Imines and Aldehydes

(2018) Jeishla L. M. Matos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Desymmetrization of cyclohexanes by site- and stereoselective C–H functionalization

(2018) Jiantao Fu et al.   NATURE

Recent Advances in the Synthetic Chemistry of Bicyclo[1.1.1]pentane

(2018) Junichiro Kanazawa et al.   SYNLETT

Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity

(2017) Justin M. Lopchuk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical Multicomponent Carboamination of [1.1.1]Propellane

(2017) Junichiro Kanazawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-selective and stereoselective functionalization of non-activated tertiary C–H bonds

(2017) Kuangbiao Liao et al.   NATURE

Toward Resolving the Resveratrol Conundrum: Synthesis and in Vivo Pharmacokinetic Evaluation of BCP–Resveratrol

(2017) Yi Ling Goh et al.   ACS Medicinal Chemistry Letters

Design, Synthesis, and Application of an Optimized Monofluorinated Aliphatic Label for Peptide Studies by Solid-State 19 F NMR Spectroscopy

(2016) Serhii O. Kokhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-selective and stereoselective functionalization of unactivated C–H bonds

(2016) Kuangbiao Liao et al.   NATURE

Strain-release amination

(2016) R. Gianatassio et al.   SCIENCE

Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA2 Inhibitor

(2016) Nicholas D. Measom et al.   ACS Medicinal Chemistry Letters

Evaluation oftert-Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities

(2015) Matthias V. Westphal et al.   ChemMedChem

2,2,2-Trichloroethyl Aryldiazoacetates as Robust Reagents for the Enantioselective C–H Functionalization of Methyl Ethers

(2014) David M. Guptill et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of Sterically Demanding Chiral Dirhodium Catalysts in Site-Selective C–H Functionalization of Activated Primary C–H Bonds

(2014) Changming Qin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Route to Bicyclo[1.1.1]pentan-1-amine from 1-Azido-3-iodobicyclo[1.1.1]pentane

(2014) Yi Ling Goh et al.   ORGANIC LETTERS

Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

(2012) Antonia F. Stepan et al.   JOURNAL OF MEDICINAL CHEMISTRY

C–H functionalization logic in total synthesis

(2011) Will R. Gutekunst et al.   CHEMICAL SOCIETY REVIEWS

Guiding principles for site selective and stereoselective intermolecular C–H functionalization by donor/acceptor rhodium carbenes

(2011) Huw M. L. Davies et al.   CHEMICAL SOCIETY REVIEWS

Scalable Synthesis of 1-Bicyclo[1.1.1]pentylamine via a Hydrohydrazination Reaction

(2011) Kevin D. Bunker et al.   ORGANIC LETTERS

Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based ω-acidic amino acids as glutamate receptors ligands

(2008) Rosanna Filosa et al.   BIOORGANIC & MEDICINAL CHEMISTRY