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Recent advances of designing dynamic surfaces to regulate cell adhesion

期刊

出版社

ELSEVIER
DOI: 10.1016/j.colcom.2020.100249

关键词

Dynamic surface; Responsive materials; Cell adhesion; Cell functions

资金

  1. National Key Research and Development Program of China [2016YFE0132700]
  2. National Natural Science Foundation of China [51673171, 51822306]
  3. Zhejiang Provincial Natural Science Foundation of China [LY20H060008]
  4. Fundamental Research Funds for the Central Universities of China [2019XZZX004-07]

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Cells are always living in a dynamic microenvironment and are able to respond to stimuli and modulate their functions. Cell adhesion is the fundamental of almost all cell behaviors, such as cell proliferation, migration, differentiation etc. Therefore, it is essential to provide a platform for studying and regulating cell adhesion in dynamic environment. Owing to the controllability of surface properties, materials with dynamic surface stand out as ideal candidates of this platform. This review summarized the recent advances of design strategies of dynamic surface, and their applications in regulating cell adhesion and related functions.

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