Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and its Primary Bioactive Compounds

Modulation of cerulein‐induced pancreatic inflammation by hydroalcoholic extract of curry leaf ( Murraya koenigii )

(2019) Amit Khurana et al.   PHYTOTHERAPY RESEARCH

Antibacterial Effect of Silver Nanoparticles Synthesized Using Murraya koenigii (L.) against Multidrug-Resistant Pathogens

(2019) Faizan Abul Qais et al.   BIOINORGANIC CHEMISTRY AND APPLICATIONS

Antibacterial, anti-inflammatory and antioxidant effects of Aegle marmelos and Murraya koenigii in dairy cows with endometritis

(2018) Rupali Rautela et al.   Livestock Science

Phytochemical portfolio and anticancer activity of Murraya koenigii and its primary active component, mahanine

(2018) Suman Kumar Samanta et al.   PHARMACOLOGICAL RESEARCH

Girinimbine Inhibits the Proliferation of Human Ovarian Cancer Cells In Vitro via the Phosphatidylinositol-3-Kinase (PI3K)/Akt and the Mammalian Target of Rapamycin (mTOR) and Wnt/β-Catenin Signaling Pathways

(2018) Qiu Xin et al.   MEDICAL SCIENCE MONITOR

Mahanimbine Exerts Anticancer Effects on Human Pancreatic Cancer Cells by Triggering Cell Cycle Arrest, Apoptosis, and Modulation of AKT/Mammalian Target of Rapamycin (mTOR) and Signal Transducer and Activator of Transcription 3 (STAT3) Signalling Pathways

(2018) Chenlin Pei et al.   MEDICAL SCIENCE MONITOR

Mahanine induces apoptosis, cell cycle arrest, inhibition of cell migration, invasion and PI3K/AKT/mTOR signalling pathway in glioma cells and inhibits tumor growth in vivo

(2018) Maohua Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Total synthesis and neuroprotective effect of O-methylmurrayamine A and 7-methoxymurrayacine

(2017) Ying-Da Zang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Pyranocarbazoles from Murraya koenigii (L.) Spreng. as antimicrobial agents

(2017) Trapti Joshi et al.   NATURAL PRODUCT RESEARCH

Dysregulated Expression of MITF in Subsets of Hepatocellular Carcinoma and Cholangiocarcinoma

(2017) Nattakarn Nooron et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Nephroprotective effect of Murraya koenigii on cyclophosphamide induced nephrotoxicity in rats

(2017) Patel Mahipal et al.   Asian Pacific Journal of Tropical Medicine

Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A

(2017) Karine Z. Oben et al.   Oncotarget

In Vivo Inhibition of Proteasome Activity and Tumour Growth by Murraya koenigii Leaf Extract in Breast Cancer Xenografts and by Its Active Flavonoids in Breast Cancer Cells

(2016) Bindu Noolu et al.   Anti-Cancer Agents in Medicinal Chemistry

Alkenes with antioxidative activities from Murraya koenigii (L.) Spreng

(2016) Qin-Ge Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cytotoxicity and Proteasome Inhibition by Alkaloid Extract from Murraya koenigii Leaves in Breast Cancer Cells—Molecular Docking Studies

(2016) Ayesha Ismail et al.   JOURNAL OF MEDICINAL FOOD

Carbazole alkaloids from Murraya koenigii trigger apoptosis and autophagic flux inhibition in human oral squamous cell carcinoma cells

(2016) Tanyarath Utaipan et al.   Journal of Natural Medicines

Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents

(2016) Om P. S. Patel et al.   JOURNAL OF NATURAL PRODUCTS

Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities

(2016) Yedukondalu Nalli et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii

(2016) Venoos Iman et al.   Drug Design Development and Therapy

Chemopreventive and immunomodulatory effects of Murraya koenigii aqueous extract on 4T1 breast cancer cell-challenged mice

(2015) Swee Keong Yeap et al.   BMC Complementary and Alternative Medicine

Targeting disease by immunomodulation

(2015) T Kaufmann et al.   CELL DEATH AND DIFFERENTIATION

Combined Effect of Hydroethanolic Extracts of Murraya Koenigii and Phyllanthus Niruri Leaves on Paracetamol and Ethanol-induced Toxicity in HepG2 Cell Line

(2015) Pallavi Shah et al.   CURRENT SCIENCE

A carbazole alkaloid deactivates mTOR through the suppression of rictor and that induces apoptosis in lung cancer cells

(2015) Priyajit Chatterjee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

In vitroantibiofilm activity ofMurraya koenigiiessential oil extracted using supercritical fluid CO2method againstPseudomonas aeruginosaPAO1

(2015) P. Sankar Ganesh et al.   NATURAL PRODUCT RESEARCH

Evaluation of antibacterial and cytotoxic activity of Artemisia nilagirica and Murraya koenigii leaf extracts against mycobacteria and macrophages

(2014) Sumanta Kumar Naik et al.   BMC Complementary and Alternative Medicine

Improved chemosensitivity in cervical cancer to cisplatin: Synergistic activity of mahanine through STAT3 inhibition

(2014) Ranjita Das et al.   CANCER LETTERS

Evaluation of aqueous extract of Murraya koenigii in unilateral renal ischemia reperfusion injury in rats

(2014) Priyanka Punuru et al.   INDIAN JOURNAL OF PHARMACOLOGY

Flavonoid rich extract of Murraya Koenigii alleviates in-vitro LDL oxidation and oxidized LDL induced apoptosis in raw 264.7 Murine macrophage cells

(2014) Tejal K. Gajaria et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Mahanine synergistically enhances cytotoxicity of 5-fluorouracil through ROS-mediated activation of PTEN and p53/p73 in colon carcinoma

(2013) Ranjita Das et al.   APOPTOSIS

Murraya koenigii leaf extract inhibits proteasome activity and induces cell death in breast cancer cells

(2013) Bindu Noolu et al.   BMC Complementary and Alternative Medicine

Apoptosis Effect of Girinimbine Isolated fromMurraya koenigiion Lung Cancer CellsIn Vitro

(2013) Syam Mohan et al.   Evidence-based Complementary and Alternative Medicine

Bioactive carbazole alkaloids from Murraya koenigii (L.) Spreng

(2013) Qinge Ma et al.   FITOTERAPIA

Chemical analysis of essential oils of Eupatorium adenophorum and their antimicrobial, antioxidant and phytotoxic properties

(2013) Vivek Ahluwalia et al.   JOURNAL OF PEST SCIENCE

Mahanine restores RASSF1A expression by down-regulating DNMT1 and DNMT3B in prostate cancer cells

(2013) Soumik Agarwal et al.   Molecular Cancer

Anti-inflammatory, analgesic and anti-ulcerogenic effect of total alkaloidal extract from Murraya koenigii leaves in animal models

(2013) Vasudevan Mani et al.   Food & Function

Antioxidant Capacity and Antimutagenic Potential ofMurraya koenigii

(2013) Maryam Zahin et al.   Biomed Research International

Protective effect of aqueous Curry leaf (Murraya koenigii) extract against cadmium-induced oxidative stress in rat heart

(2012) Elina Mitra et al.   FOOD AND CHEMICAL TOXICOLOGY

Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinomain vitroandin vivo

(2012) Sayantani Sarkar et al.   INTERNATIONAL JOURNAL OF CANCER

Efficacy of Carbazole Alkaloids, Essential Oil and Extract of Murraya koenigii in Enhancing Subcutaneous Wound Healing in Rats

(2012) Thilahgavani Nagappan et al.   MOLECULES

Effects of the Total Alkaloidal Extract ofMurraya koenigiiLeaf on Oxidative Stress and Cholinergic Transmission in Aged Mice

(2012) Vasudevan Mani et al.   PHYTOTHERAPY RESEARCH

Protective effects of total alkaloidal extract from Murraya koenigii leaves on experimentally induced dementia

(2011) Vasudevan Mani et al.   FOOD AND CHEMICAL TOXICOLOGY

Hepatoprotective potential of polyphenol rich extract of Murraya koenigii L.: An in vivo study

(2011) Swati N. Desai et al.   FOOD AND CHEMICAL TOXICOLOGY

Immunomodulatory effect of leaf extract ofMurraya koenigiiin diabetic mice

(2011) S. Paul et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

A new carbazole alkaloid from the leaves of MalayanMurraya koenigii

(2011) Kooi-Mow Sim et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Beneficial effect of the leaves of Murraya koenigii (Linn.) Spreng (Rutaceae) on diabetes-induced renal damage in vivo

(2011) Hassan Yankuzo et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Growth Suppressing Effects of Girinimbine on Hepg2 Involve Induction of Apoptosis and Cell Cycle Arrest

(2011) Suvitha Syam et al.   MOLECULES

Hepatoprotective effects of aqueous leaf extract and crude isolates of Murraya koenigii against in vitro ethanol-induced hepatotoxicity model

(2010) Sadhana Sathaye et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways

(2009) Kaushik Bhattacharya et al.   BIOCHEMICAL PHARMACOLOGY

Antidiarrhoeal activity of carbazole alkaloids from Murraya koenigii Spreng (Rutaceae) seeds

(2009) Suvra Mandal et al.   FITOTERAPIA

Potent antibacterial property of APC protein from curry leaves (Murraya koenigii L.)

(2009) Mylarappa B. Ningappa et al.   FOOD CHEMISTRY

Mitochondria and reactive oxygen species

(2009) Alicia J. Kowaltowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Therapeutic approaches to mitochondrial dysfunction in Parkinson's disease

(2009) M. Flint Beal   PARKINSONISM & RELATED DISORDERS

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Antiamnesic potential ofMurraya koenigiileaves

(2008) Mani Vasudevan et al.   PHYTOTHERAPY RESEARCH

Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1α-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer

(2007) Stephen L. Archer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY