Article
Food Science & Technology
Marasri Junsi, Sunisa Siripongvutikorn
Summary: The aqueous crude extracts of Thunbergia laurifolia leaves can enhance antioxidant enzyme activity and reduce lipid peroxidation levels. It also exhibits a protective effect against insecticides. Further research is needed to ensure its safety in functional drinks.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Wudtipong Vongthip, Chanin Sillapachaiyaporn, Kyu-Won Kim, Monruedee Sukprasansap, Tewin Tencomnao
Summary: Thunbergia laurifolia leaf extract (TLE) is rich in bioactive antioxidants and can protect neuronal cells by stimulating endogenous antioxidant enzymes, inhibiting oxidative toxicity, and modulating mitophagy-autophagy pathway.
Article
Chemistry, Applied
Anh-Khoa Nguyen, Preecha Phuwapraisirisan
Summary: A new compound named 5-acetoxyfuranonapthoquinone (1) was isolated from Thunbergia laurifolia L stems, along with nineteen known compounds (220). The structures of the isolated compounds were determined by spectroscopic analysis. The isolated compounds were evaluated for their inhibitory activity against alpha-glucosidase. Syringaresinol (7), rosmarinic acid (11), 1,2,8-trihydroxyxanthone (16), and isojacareubin (18) exhibited the most potent inhibitory activity. Kinetic study revealed that syringaresinol (7), 1,2,8-trihydroxyxanthone (16) and isojacareubin (18) inhibited maltase and sucrase activity in a non-competitive manner, while rosmarinic acid (11) showed non-competitive inhibition against maltase and mixed-mode inhibition against sucrase.
NATURAL PRODUCT RESEARCH
(2022)
Article
Plant Sciences
Thanawat Pattananandecha, Sutasinee Apichai, Jakaphun Julsrigival, Malyn Ungsurungsie, Suched Samuhasaneetoo, Pat Chulasiri, Pakakrong Kwankhao, Supaporn Pitiporn, Fumihiko Ogata, Naohito Kawasaki, Chalermpong Saenjum
Summary: The study showed that SRAEE exhibited antioxidant activity and inhibited the production of ROS, MMP-1, and other substances in cell-based studies and in vitro, making it a potential candidate for natural pharmaceutical ingredient in cosmeceutical products.
Article
Biochemistry & Molecular Biology
Nanthakarn Woottisin, Sophida Sukprasert, Thitianan Kulsirirat, Thipaporn Tharavanij, Korbtham Sathirakul
Summary: This study investigated the permeability of rosmarinic acid (RA) in Thunbergia laurifolia (TL) extract and as a pure compound. The results showed that the permeability of RA significantly increased after deconjugation. RA was transported through Caco-2 cells via passive diffusion. RA in TL extract mainly penetrated as conjugated forms with glucuronic acid and/or sulfate.
Article
Food Science & Technology
Mercedes Taroncher, Fiona Halbig, Yelko Rodriguez-Carrasco, Maria-Jose Ruiz
Summary: The antioxidant defense system in HepG2 cells was evaluated against oxidative stress induced by T-2 toxin and its metabolites. The study found that the antioxidant enzymes system can alleviate the damage caused by T-2 and its metabolites in HepG2 cells.
Article
Food Science & Technology
Justice A. Essiedu, Hellie Gonu, Parise Adadi, Ulaiwan Withayagiat
Summary: The Thunbergia laurifolia leaf is used in Thai herbal medicine for its health benefits. This study investigated the effects of different drying conditions on the phenolic compounds and antioxidant activities of the infused teas. The results suggest that a specific drying condition can preserve the phytochemical compositions and antioxidant potentials of the tea leaves.
JOURNAL OF FOOD QUALITY
(2023)
Article
Environmental Sciences
Guoqiang Liu, Xuanzhu Gu, Jing Wu, Haidong Li, Lianghu Su, Mei Chen, Sujuan Chen, Yonghua Liu
Summary: In real-field soil conditions, the co-occurrence of microplastics (MPs) and cadmium (Cd) is common and may pose potential risks to soil ecosystems. This study evaluated the effects of biodegradable MPs (PLA) and Cd on a soil animal Folsomia candida. The results showed that both single and combined PLA and Cd had negative influences on the survival, reproduction, and growth of F. candida, with the effects intensifying at higher PLA concentrations. However, combined PLA and Cd alleviated the toxicity of Cd at lower PLA concentrations. The study also suggested that MP treatment may be a promising biomarker for soil collembolan in assessing soil MP exposure.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Mariko Shiraiwa, Tomoya Kitakaze, Yoko Yamashita, Yuichi Ukawa, Katsuyuki Mukai, Hitoshi Ashida
Summary: Pectolinarigenin (PG) and its glycoside pectolinarin (PN) have various health benefits and direct antioxidant activity. This study found that PG can indirectly induce the expression of antioxidant enzymes through the Nrf2/ARE pathway, thus protecting the liver from oxidative stress.
Article
Biochemistry & Molecular Biology
Juan Luis Penas-Fuentes, Eva Siles, Eva E. Rufino-Palomares, Amalia Perez-Jimenez, Fernando J. Reyes-Zurita, Jose A. Lupianez, Carlos Fuentes-Almagro, Juan Peragon-Sanchez
Summary: This study characterized the cytotoxic effects of erythrodiol (EO) on human hepatocarcinoma cells. EO decreased cell viability and antioxidant defense systems, impaired important metabolic processes and nuclear transport, but induced AMP biosynthesis and cell cycle G2/M phase transition.
Article
Multidisciplinary Sciences
Sarawoot Palipoch, Chuchard Punsawad, Phanit Koomhin, Wasinee Poonsawat
Summary: The study found that TL aqueous leaf extract can ameliorate PQ-induced kidney injury by regulating oxidative stress through inhibiting NOX, especially NOX-1 and NOX-4 expressions.
Article
Biochemistry & Molecular Biology
Kumari Pragati Nanda, Hena Firdaus
Summary: Exposure to Cd was found to lower the count of blood cells in Drosophila larvae, likely due to changes in antioxidant enzyme activity, decreased levels of antioxidants, and induction of apoptosis in the hemocytes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Agronomy
Xiaoqin Tan, Jiacheng Huang, Lijin Lin, Qian Tang
Summary: This study explored the feasibility of using melatonin to alleviate Cd toxicity and reduce Cd accumulation in tea seedlings. The results showed that melatonin promoted tea seedling growth, increased photosynthetic pigment and soluble protein content. Moreover, melatonin enhanced the antioxidant capacity of plants, reduced oxidative damage, and improved soil enzyme activities.
Article
Environmental Sciences
Furkan Orhan, Kadriye Uruc Parlak, Dilruba Tabay, Sedat Bozari
Summary: This study tested the alleviation effect of ectoine, which has been widely studied, on cadmium (Cd) toxicity. The results show that ectoine has no detrimental effect on plant (wheat) germination rate, antioxidant enzyme levels, H(2)O(2) and MDA contents, but co-treatment of ectoine with Cd significantly alleviated Cd toxicity. This study reports for the first time that ectoine has an amelioration effect on Cd toxicity.
WATER AIR AND SOIL POLLUTION
(2023)
Article
Entomology
Yu Zhang, Wenhui Xiong, Shan Yang, Hui Ai, Zhiwen Zou, Bin Xia
Summary: This study showed that long-term exposure to cadmium adversely affected the development, reproduction, and physiology of Aleuroglyphus ovatus. A. ovatus proved to be a sensitive organism for studying the toxicity of long-term heavy metal exposure on offspring. The findings also provided a basis for future evaluation of cadmium pressure on genetic evolution.
Article
Biochemical Research Methods
Dominik Wuellner, Annika Haupt, Pascal Prochnow, Roman Leontiev, Alan J. Slusarenko, Julia E. Bandow
Article
Chemistry, Multidisciplinary
Ivan Schlembach, Andreas Uebachs, Tim Caspers, Athanassios Fragoulis, Alan J. Slusarenko, Martin C. H. Gruhlke
APPLIED SCIENCES-BASEL
(2020)
Review
Biochemistry & Molecular Biology
Jan Borlinghaus, Jana Foerster (nee Reiter), Ulrike Kappler, Haike Antelmann, Ulrike Noll, Martin C. H. Gruhlke, Alan J. Slusarenko
Summary: Allicin is a volatile organic sulfur compound produced as a defense substance in garlic when tissues are damaged, exhibiting membrane permeability and antimicrobial activity. It can induce apoptosis or necrosis at high doses in eukaryotes, while lower amounts can modulate protein activity and affect cellular signaling. This review summarizes the specific effects of allicin on bacterial and eukaryotic cells.
Article
Biochemistry & Molecular Biology
Christina Schier, Jana Foerster (nee Reiter), Monika Heupel, Philipp Doerner, Michael Klaas, Wolfgang Schroeder, Lothar Rink, Alan J. Slusarenko, Martin C. H. Gruhlke
Summary: Allicin, a volatile substance produced by injured garlic plants, shows broad antimicrobial activity against selected fungi. It has comparable efficacy to the commonly used antifungal drug amphotericin B. Our study suggests that allicin may be a potential candidate for antifungal therapy in lung and upper respiratory tract infections.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Food Science & Technology
Sunisa Siripongvutikorn, Worapong Usawakesmanee, Supachai Pisuchpen, Nicha Khatcharin, Chanonkarn Rujirapong
Summary: This study examined the nutritional content and microbial load of Liang leaves at different maturity stages and the effects of washing with chlorinated water. Results showed that Liang leaves have distinct nutritional profiles, with intermediate leaves being high in dietary fiber and abundant in essential amino acids and proteins. Washing with chlorinated water can reduce microbial counts, but stem detachment during washing can increase the counts of coliform and Escherichia coli.
Article
Food Science & Technology
Marasri Junsi, Sunisa Siripongvutikorn
Summary: Centella asiatica, also known as Bua Bog, has been used as an important medicinal herb in Thailand for over a hundred years. This study aimed to investigate the effect of blanching time on the antioxidant activity of C. asiatica. Furthermore, the sensory evaluation, nutritional value, and shelf life of developed-pasteurized C. asiatica juice were also assessed. The results showed that blanching the leaves for 2 minutes resulted in the highest total extractable phenolic content (TPC), total extractable flavonoid content (TFC), and antioxidant activity. Additionally, the low sugar (LS) level was chosen for pasteurization and the juice could be stored at 8 degrees C for 10 days. Therefore, C. asiatica can be utilized as a pasteurized juice and consumed as a functional drink.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Food Science & Technology
Nata ANISONG, Sunisa SIRIPONGVUTIKORN, santad WICHIENCHOT, Panupong PUTTARAK
Summary: This review article focuses on the nutritional constituents and functional properties of Gnetum gnemon Linn. The fruit or seed of G. gnemon has been extensively utilized and studied for food products in India and Indonesia. It is a good source of protein with complete amino acids and high branched-chain amino acids. Additionally, G. gnemon has high contents of vitamin A, dietary fiber, minerals, and chlorophylls, which contribute to various health benefits.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Marasri Junsi, Sunisa Siripongvutikorn
Summary: The aqueous crude extracts of Thunbergia laurifolia leaves can enhance antioxidant enzyme activity and reduce lipid peroxidation levels. It also exhibits a protective effect against insecticides. Further research is needed to ensure its safety in functional drinks.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Chanonkarn Rujirapong, Sunisa Siripongvutikorn, Worapong Usawakesmanee, Bandhita Wanikorn
Summary: This study aimed to produce a reduced sodium shrimp head paste as an alternative raw material in shrimp paste production. It found that using shrimp head can lower the salt content and reduce the associated health risks.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Tobias Horn, Wolfgang Bettray, Ulrike Noll, Felix Krauskopf, Meng-Ruo Huang, Carsten Bolm, Alan J. Slusarenko, Martin C. H. Gruhlke
Article
Biology
Jan Borlinghaus, Anthony Bolger, Christina Schier, Alexander Vogel, Bjoern Usadel, Martin C. H. Gruhlke, Alan J. Slusarenko
LIFE SCIENCE ALLIANCE
(2020)
Article
Food Science & Technology
Nguyen Phung Tien, Sunisa Siripongvutikorn, Worapong Usawakesmanee
FOODS AND RAW MATERIALS
(2019)