Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics

Multidimensional imaging provides evidence for down-regulation of T cell effector function by MDSC in human cancer tissue

(2019) Yu Si et al.   Science Immunology

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

(2018) Elham Azizi et al.   CELL

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

(2018) Amir Giladi et al.   NATURE CELL BIOLOGY

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

CD84 cell surface signaling molecule: An emerging biomarker and target for cancer and autoimmune disorders

(2018) Marta Cuenca et al.   CLINICAL IMMUNOLOGY

CD84 regulates PD-1/PD-L1 expression and function in chronic lymphocytic leukemia

(2018) Hadas Lewinsky et al.   JOURNAL OF CLINICAL INVESTIGATION

CD33/CD3-bispecific T-cell engaging (BiTE®) antibody construct targets monocytic AML myeloid-derived suppressor cells

(2018) Regina Jitschin et al.   Journal for ImmunoTherapy of Cancer

Splenic Ly6G high mature and Ly6G int immature neutrophils contribute to eradication of S. pneumoniae

(2017) Justin F. Deniset et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD84 mediates CLL-microenvironment interactions

(2016) A Marom et al.   ONCOGENE

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Interferon-induced transmembrane protein 1 (IFITM1) is required for the progression of colorectal cancer

(2016) Ita Novita Sari et al.   Oncotarget

IFITM1 promotes the metastasis of human colorectal cancer via CAV-1

(2015) Fang Yu et al.   CANCER LETTERS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17–producing CD4+T cells

(2015) Myrna L. Ortiz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils

(2015) Amy-Jo Casbon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression

(2015) G. Wang et al.   Cancer Discovery

CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function

(2015) Eunyoung Chun et al.   Cell Reports

CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis

(2014) Hideyo Hirai et al.   CLINICAL & EXPERIMENTAL METASTASIS

Roles and regulation of phospholipid scramblases

(2014) Karthik M. Kodigepalli et al.   FEBS LETTERS

Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells

(2014) P. Sinha et al.   JOURNAL OF IMMUNOLOGY

Neutrophil-derived JAML inhibits repair of intestinal epithelial injury during acute inflammation

(2014) D A Weber et al.   Mucosal Immunology

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 Efficacy

(2014) S. L. Highfill et al.   Science Translational Medicine

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Response to Comment on "Myeloid-Derived Suppressor Cells Suppress Antitumor Immune Responses through IDO Expression and Correlate with Lymph Node Metastasis in Patients with Breast Cancer"

(2013) J. Yu et al.   JOURNAL OF IMMUNOLOGY

Endogenous and Natural Complement Inhibitor Attenuates Myocardial Injury and Arterial Thrombogenesis

(2012) Vasile I. Pavlov et al.   CIRCULATION

Paired Immunoglobin-like Receptor-B Regulates the Suppressive Function and Fate of Myeloid-Derived Suppressor Cells

(2011) Ge Ma et al.   IMMUNITY

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

(2010) S. L. Highfill et al.   BLOOD

The Novel Activated Microglia/Macrophage WAP Domain Protein, AMWAP, Acts as a Counter-Regulator of Proinflammatory Response

(2010) M. Karlstetter et al.   JOURNAL OF IMMUNOLOGY

Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells

(2010) M. G. Lechner et al.   JOURNAL OF IMMUNOLOGY

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

(2008) C. Marcela Diaz-Montero et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cancer exploiting complement: a clue or an exception?

(2008) Bruce E Loveland et al.   NATURE IMMUNOLOGY