Article
Biochemistry & Molecular Biology
Caihong Wang, Zhijie Zhu, Liping Mei, Yaoyao Xia, Xu Chen, Saddam Mustafa, Xianfeng Du
Summary: This study investigated the effects of pullulanase debranching on the structural properties and digestibility of maize starch-glyceryl monostearate complexes. The results showed that pullulanase debranching for 16 hours significantly increased the amylose content and complex index of maize starch. The crystallinity and short-range orders structure of the complexes also increased, leading to a higher resistant starch content and anti-digestibility. This work suggests that debranching pretreatment is an efficient way to produce ordered starch-lipid complexes with controllable structure and anti-digestibility.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Hongrui Sun, Jieying Fan, Zhigang Tian, Linyuan Ma, Yue Meng, Zhiqiang Yang, Xianpeng Zeng, Xiangying Liu, Lining Kang, Xiping Nan
Summary: All three treatments were able to transform the starch crystalline structure from C-type to B-type, resulting in the formation of resistant starch from purple sweet potato. Resistant starch prepared via pullulanase-autoclaving combination treatment exhibited the highest gelatinisation enthalpy value and the greatest degree of overall thermal stability.
Article
Biotechnology & Applied Microbiology
Monika Thakur, Amit K. Rai, Bhuwan B. Mishra, Sudhir P. Singh
Summary: This study extracted starch from potato peel to produce RS3 and maltodextrins, demonstrating the potential of using potato peel biomass to produce high-value bio-products.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Polymer Science
Nasima Chorfa, Herve Nlandu, Khaled Belkacemi, Safia Hamoudi
Summary: In this work, valorization of downgraded potatoes' starch was achieved through the preparation of starch nanoparticles using different physical methods and enzymatic hydrolysis. The physical modification methods led to moderate alterations in the size and crystallinity of the starch granules, while enzymatic hydrolysis using Pullulanase enzyme resulted in the production of very small starch nanoparticles. The effects of enzyme concentration, temperature, and pH on the hydrolysis process were also investigated.
Article
Chemistry, Applied
Xiangzhen Ge, Huishan Shen, Chunyan Su, Bo Zhang, Qian Zhang, Hao Jiang, Li Yuan, Xiuzhu Yu, Wenhao Li
Summary: This study explored the potential application of physical combined enzyme treatment to modify starch granules. The CP-PUL combined treatment significantly promoted the subsequent structural modification of starch, increased the short-chain ratio and amylose content, reduced the molecular weight and relative crystallinity, and disturbed the short-range order.
CARBOHYDRATE POLYMERS
(2021)
Article
Materials Science, Paper & Wood
Herve M. Nlandu, Nasima Chorfa, Khaled Bekacemi, Safia Hamoudi
Summary: Starch nanocrystals were successfully produced from downgraded potatoes using enzymatic hydrolysis combined with a supercritical carbon dioxide pretreatment to improve enzyme accessibility. Characterization techniques such as TEM, SEM, FTIR, and XRD were used to compare the materials. The study found that the crystallinity of potato starch nanoparticles significantly increased after supercritical carbon dioxide pretreatment, forming nanostructures ranging from 80 nm to 150 nm in diameter.
Article
Biochemistry & Molecular Biology
Zhenjiong Wang, Zheng Xing, Qin Zhang, Dongxia Hu, Jiasheng Lv, Chaoyi Wu, Wenzhi Zhou, Zia-ud-Din
Summary: This study investigated the effects of enzymatic hydrolysis on starch-based wood adhesive (SWA) and found that moderate enzymatic hydrolysis for 2 hours could improve the adhesive properties, including increased bonding strength, decreased viscosity, better elastic deformation, and smoother surfaces. This provides valuable information for the potential application of SWA in the wood industry as an environmentally friendly alternative to formaldehyde-based adhesives.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Chagam Koteswara Reddy, Su Young Son, Choong Hwan Lee
Summary: The study demonstrates that debranched maize starch can form inclusion complexes with catechin-rich green tea ethanolic extract, showing high recovery yield and stability.
FOOD HYDROCOLLOIDS
(2021)
Article
Food Science & Technology
David Mahoudjro Bodjrenou, Xin Li, Wei Chen, Yi Zhang, Baodong Zheng, Hongliang Zeng
Summary: The effect of pullulanase debranching combined with autoclaving on the characteristics of purple sweet potato starch was investigated. It was found that the treatment resulted in rougher surface, smaller molecular weight, increased crystallinity, and higher yield of resistant starch.
Article
Food Science & Technology
Sang Hoon Lee, Wen Yan Huang, Jinhee Hwang, Hyeock Yoon, Wan Heo, Jiyoun Hong, Mi Jeong Kim, Chang-Soo Kang, Bok Kyung Han, Young Jun Kim
Summary: This study evaluated the properties of amylose-lipid complexes in rice and wheat flours using pullulanase as a debranching enzyme. The treated compounds, RPF and FPF, exhibited higher complex index, lower hydrolysis values, lower swelling power, and higher water solubility values compared to enzyme-untreated complexes. In vivo studies showed that RPF and FPF had a smaller impact on blood glucose levels, suggesting their potential as functional food ingredients.
FOOD SCIENCE AND BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Zijun Liu, Nan Deng, Shunjing Luo, Chengmei Liu, Xiuting Hu
Summary: This study investigated the fermentation of resistant starch from the starch-ferulic acid inclusion complex. The results showed that the complex-based resistant starch, high-amylose corn starch, and the mixture of ferulic acid and high-amylose corn starch were mainly utilized initially. Additionally, the complex-based resistant starch led to the highest production of short-chain fatty acids (SCFAs), the lowest ratio of Firmicutes/Bacteroidetes (F/B), and the most abundance of beneficial bacteria.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Hua Li, Fengyan Zhai, Jianfeng Li, Xuanxuan Zhu, Yanyan Guo, Beibei Zhao, Baocheng Xu
Summary: The study investigated the physicochemical, rheological properties and structure of potato starch and starch-tea polyphenols (TPs) complex modified by enzyme and alcohol. TPs inhibited the aggregation of amylose and retrogradation of starch TPs complex, resulting in decreased gel strength, increased viscosity, and gelatinization stability of starch granules. The formation of complex between TPs and native/modified potato starch could be used in food industrial applications due to the inhibition of starch retrogradation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Agricultural Engineering
Monika Thakur, Nitish Sharma, Amit K. Rai, Sudhir P. Singh
Summary: A novel type I pullulanase (PulM) with optimal debranching activity at 40 degrees C and pH 6.0 to 7.0 was identified in this study. PulM showed cold-active properties with over 50% enzymatic activity detected at 4 degrees C. The enzyme efficiently catalyzed the hydrolysis of alpha-1,6-glycosidic linkages in pullulan and increased the apparent amylose content of potato starch by about 80%. The debranched starch led to the formation of resistant starch 3, which exhibited higher crystallinity, enhanced heat-stability, and resistance to alpha-amylase digestion compared to native starch.
BIORESOURCE TECHNOLOGY
(2021)
Article
Chemistry, Applied
Jyoti Semwal, M. S. Meera
Summary: Papain-pretreated sorghum grains were modified using pullulanase and infrared irradiation to reduce starch digestibility. The combination of pullulanase (1 U/ml/5h) and IR (220°C/3 min) treatment showed the best synergistic effect, producing modified corneous endosperm starch with a hydrolysis rate of 0.022, a hydrolysis index of 42.58, and a potential digestibility of 0.468. The modification increased the amylose content and crystallinity of the starch, but decreased its swelling power, solubility index, and pasting properties. The combination of debranching and infrared treatment can be an efficient method to produce tailor-made starch for food industries.
Article
Agriculture, Multidisciplinary
Mushawah Abdullah Almushawah, Jegan Athinarayanan, Vaiyapuri Subbarayan Periasamy, Ali A. Alshatwi
Summary: In this study, myristic acid-potato starch complex-based nanostructured materials were fabricated using a cooking approach. The structural and cytotoxic features of these materials were investigated, revealing their potential negative effects on cell metabolism.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Food Science & Technology
Weiwei Cheng, Da-Wen Sun, Hongbin Pu, Yuwei Liu
LWT-FOOD SCIENCE AND TECHNOLOGY
(2016)
Article
Chemistry, Applied
Weiwei Cheng, Da-Wen Sun, Hongbin Pu, Qingyi Wei
Article
Engineering, Chemical
Qian Yang, Da-Wen Sun, Weiwei Cheng
JOURNAL OF FOOD ENGINEERING
(2017)
Article
Chemistry, Applied
Weiwei Cheng, Da-Wen Sun, Hongbin Pu, Qingyi Wei
Article
Chemistry, Applied
Weiwei Cheng, Da-Wen Sun, Hongbin Pu, Qingyi Wei
Article
Engineering, Chemical
Weiwei Cheng, Da-Wen Sun, Hongbin Pu, Qingyi Wei
JOURNAL OF FOOD ENGINEERING
(2019)
Article
Food Science & Technology
Weiwei Cheng, Klays M. Sorensen, Richard J. Mongi, Bernadette K. Ndabikunze, Bernard E. Chove, Da-Wen Sun, Soren B. Engelsen
LWT-FOOD SCIENCE AND TECHNOLOGY
(2019)
Article
Engineering, Chemical
Weiwei Chen, Klays Martin Sorensen, Soren Balling Engelsen, Da-Wen Sun, Hongbin Pu
JOURNAL OF FOOD ENGINEERING
(2019)
Article
Food Science & Technology
Weiwei Cheng, Xiaozhi Tang, Yan Zhang, Di Wu, Wenjian Yang
Summary: Metal-organic frameworks (MOFs) have exhibited outstanding sensing performance in food safety control sensors. Despite the great potential demonstrated by MOF-based materials, further research is needed before practical applications. With the development of new synthesis and modification techniques, sensors using MOFs as sensing materials are promising to improve food safety sensing efficiency.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Food Science & Technology
Weiwei Cheng, Xi Wu, Yan Zhang, Di Wu, Linghan Meng, Yumin Chen, Xiaozhi Tang
Summary: This review summarizes the recent applications of hydrogel-based materials in sensors for detecting harmful substances in food. The performance of hydrogel-based sensors in analyzing optical, electrical, chemical, or biological signals is highlighted. Despite their potential, challenges still need to be addressed before hydrogel-based sensors can be widely used in commercial food safety control systems.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Applied
Jiayu Cheng, Jiayu Wang, Fenglian Chen, Di Wu, Chengcheng Gao, Weiwei Cheng, Zhenjiong Wang, Xinchun Shen, Xiaozhi Tang
Summary: In this study, low temperature extrusion-modified potato starch (MPS) was added to improve properties of whole wheat dough and textural quality of resulted youtiao. The low temperature extrusion processing caused moderate gelatinization and improved gel-forming properties of potato starch. The addition of MPS decreased the setback, enhanced the viscoelasticity of whole wheat dough, and improved the texture properties of whole wheat youtiao.
Article
Food Science & Technology
Yumin Chen, Linxuan Zhu, Yuling Yang, Di Wu, Yan Zhang, Weiwei Cheng, Xiaozhi Tang
Summary: A high-performance Au@MIL-101/PMMA/DT surface-enhanced Raman scattering (SERS) substrate was fabricated for sensitive and stable detection of paraquat by self-assembling metal organic framework-modified Au nanoparticles (Au@MIL-101) on a poly(methyl methacrylate) (PMMA) film and then immobilizing the formed substrate onto a duct tape (DT). The substrate exhibited outstanding uniformity with relative standard deviations of 9.47% and storage stability for 2 months. For detecting paraquat, the substrate showed a low detection limit of 7.1 x 10(-9) M (1.83 μg/kg) and wide linear range from 10(-8) to 10(-2) M. Furthermore, the substrate showed good detection performance in real cereal samples with desirable recovery rates from 91.57% to 102.32%.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Food Science & Technology
Weiwei Cheng, Li Gao, Di Wu, Chengcheng Gao, Linghan Meng, Xiao Feng, Xiaozhi Tang
LWT-FOOD SCIENCE AND TECHNOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Xuyang Sun, Chen Yu, Meixia Fu, Di Wu, Chengcheng Gao, Xiao Feng, Weiwei Cheng, Xinchun Shen, Xiaozhi Tang
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)