Article
Agriculture, Dairy & Animal Science
Jairo Apaez-Barrios, Juan Ocampo-Lopez, Sergio Soto-Simental, Victoria Guadalupe Aguilar-Raymundo, Maricela Ayala-Martinez
Summary: This study investigated the impact of using Pithecellobium dulce fruit as a feed for rabbits on their productive performance, carcass traits, meat characteristics, and meat product quality. The results showed that inclusion of 0.5% of P. dulce fruit in the diet improved the shelf-life of rabbit meat and increased the acceptance of meatballs prepared from that meat in sensory analysis.
Article
Chemistry, Applied
Sara Saeed Kotb, Iriny M. Ayoub, Safaa A. El-Moghazy, Abdel Nasser B. Singab
Summary: The metabolites profile of Egyptian P. dulce bark, rich in polyphenols and flavonoids, was analyzed using UPLC-ESI-MS/MS. The bark showed promising antioxidant and cytotoxic activities, but weak antimicrobial activity. In silico molecular docking study revealed good interaction energy between daidzein compound and the target protein.
NATURAL PRODUCT RESEARCH
(2022)
Article
Plant Sciences
Satyam Kumar Kumbhakar, Ravishankar Chauhan, Vikram Singh, S. K. Jadhav, Afaque Quraishi
Summary: A study found that citric acid could alleviate the effects of Pb stress on the growth, biochemistry, and genomic stability of P. dulce seedlings.
BRAZILIAN JOURNAL OF BOTANY
(2022)
Article
Chemistry, Applied
Watsika Wichaidit, Panumart Thongyoo
Summary: A newly isolated compound, 3-(hydroxymethyl)-4-(methylamino)-dihydrofuran-2(3H)-one (1), from the leaves of Pithecellobium dulce (Roxb.) Benth., demonstrated promising xanthine oxidase inhibitory activity.
NATURAL PRODUCT RESEARCH
(2023)
Article
Plant Sciences
Agustin Olmedo-Juarez, Ana Laura Jimenez-Chino, Alejandro Bugarin, Alejandro Zamilpa, Pedro Mendoza-de Gives, Abel Villa-Mancera, Maria Eugenia Lopez-Arellano, Jaime Olivares-Perez, Edgar Jesus Delgado-Nunez, Manases Gonzalez-Cortazar
Summary: This study evaluated the ovicidal activity of P. dulce plant against Haemonchus contortus eggs and identified the active compounds. The results indicate that P. dulce can be used for the control of gastrointestinal nematodes in small ruminants.
Article
Chemistry, Applied
Gabriela Lopez-Angulo, Sara Elizabeth Verdugo-Gaxiola, Julio Montes-Avila, Sylvia Paz Diaz-Camacho, Valentin Miranda-Soto, Nancy Yareli Salazar-Salas, Francisco Delgado-Vargas
Summary: The study found that the extract from Pithecellobium dulce fruit has anti-parasitic activity against Hymenolepis nana, showing potential for treating human infections. The purified compound N-malonyl-(+)-tryptophan was more effective than the current standard drug, praziquantel. Toxicity and ADMET prediction results supported the safety and efficacy of the tested fractions/compound.
NATURAL PRODUCT RESEARCH
(2021)
Article
Plant Sciences
Pramod Sivan, Karumanchi S. Rao
Summary: This study investigated the ultrastructural changes during different developmental/secretion stages of extrafloral nectaries (EFNs) of Pithecellobium dulce. The cytoplasm of young nectariferous cells during the pre-secretion stage was dense and characterized by active biosynthesis mechanisms. The secretory phase showed distinct changes in cytoplasm associated with endomembrane transport and the subsequent appearance of secretions in intercellular and subcuticular spaces. Advanced stages of nectar secretion revealed cell wall loosening and the formation of subcuticular spaces. The structural evidence suggests the occurrence of two modes of secretion (merocrine and holocrine) in the EFNs of P. dulce.
Article
Acoustics
Nitzia Thalia Flores-Jimenez, Jose Armando Ulloa, Judith Esmeralda Urias-Silvas, Jose Carmen Ramirez-Ramirez, Pedro Ulises Bautista-Rosales, Ranferi Gutierrez-Leyva
Summary: The study found that ultrasound treatment significantly altered the physicochemical and functional properties of guamuchil seed protein isolate (GSPI), including changes in protein structures, increased hydrophobicity and digestibility, as well as improvements in emulsifying, foaming, gelling, and other functional properties.
ULTRASONICS SONOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Yi-Peng Bai, Hui-Ming Zhou, Ke-Rui Zhu, Qin Li
Summary: The present study aimed to investigate the influence of thermal processing on the water-soluble polysaccharides in chickpeas. It was found that thermal processing caused cell wall breakage and increased the extraction rate of polysaccharides. However, it also led to a decrease in branching degree and molecular weights, as well as changes in the structure and thermal stability of polysaccharides. Interestingly, thermal processing enhanced the antioxidant activities of the polysaccharides.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Pharmacology & Pharmacy
Rajesh Kumar, Shazia Usmani, Brijesh Singh, Om Prakash, Poonam Verma, Shadma Wahab, Shabana Khatoon
Summary: Pithecellobium dulce is a medicinal plant with high nutritional value and rich active constituents, which has been widely used for the treatment and prevention of various diseases, and its medicinal properties have been confirmed by modern scientific research.
ANNALS OF PHYTOMEDICINE-AN INTERNATIONAL JOURNAL
(2022)
Article
Energy & Fuels
C. R. Mahesha, G. Jamuna Rani, Vinjamuri S. N. C. H. Dattu, Yarrapragada K. S. S. Rao, J. Madhusudhanan, L. Natrayan, S. Chandra Sekhar, Ravishankar Sathyamurthy
Summary: This study aims to produce biodiesel from Pithecellobium dulce seed oil using the transesterification process. The impact of operating variables on the yield of biodiesel was investigated, and an optimal yield was determined using response surface technique. The quality of the produced biodiesel was assessed and met the ASTM D6751 standards.
Article
Food Science & Technology
Nitzia Thalia Flores-Jimenez, Jose Armando Ulloa, Rosa Isela Ortiz-Basurto, Judith Esmeralda Urias-Silvas
Summary: The application of high-intensity ultrasound (USon) on the rheological properties of guamuchil seed protein isolate (GPI) was evaluated in this study. The results showed that USon increased the storage and loss moduli of GPI, while decreasing the loss tangent. Particularly at high power (600 W), USon led to the formation of a stronger and more elastic dispersion. Compared to native GPI, USon treatment at low (200 W) and high (600 W) power resulted in the largest decreases in apparent viscosity and noticeable shear thinning behavior. The rheological improvement of GPI by USon could be attributed to structural changes that modified inter and intramolecular interactions.
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
(2023)
Article
Integrative & Complementary Medicine
Masuma Akter, Mst Shahnaj Parvin, Md Mahadi Hasan, Md Aziz Abdur Rahman, Md Ekramul Islam
Summary: In this study, a purified compound named kaempferol-3-O-alpha-L-rhamnoside was isolated from the leaves of Pithecellobium dulce (Roxb.). The compound exhibited strong antioxidant activity and anti-tumor activity, effectively inhibiting oxidative damage in DNA and human erythrocytes, scavenging harmful free radicals, and inhibiting tumor cell growth.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2022)
Article
Food Science & Technology
Xianxiang Chen, Wenhao Xiao, Mingyue Shen, Qiang Yu, Yi Chen, Jun Yang, Jianhua Xie
Summary: This study found that storage times affect the health benefits of Mesona chinensis Benth. Fresh Mesona chinensis Benth polysaccharides have stronger antioxidant and antitumor activities compared to those stored for 1 year. The change in physicochemical properties is responsible for the decreased bioactivities.
CURRENT RESEARCH IN FOOD SCIENCE
(2022)
Article
Chemistry, Analytical
Simei Darinel Torres Landa, Inderbir Kaur, Vivechana Agarwal
Summary: Luminescent carbon dots synthesized from Pithecellobium dulce leaves were used as optical nanosensors. The carbon dots exhibited a crystalline nature and high sensitivity towards 4-nitrophenol and Cr(VI), making them potential candidates for environmental pollution monitoring.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)