Article
Materials Science, Paper & Wood
Shichen Yuan, Maksim Tyufekchiev, Michael T. Timko, Klaus Schmidt-Rohr
Summary: The quantification of reducing chain ends in hydrolyzed cellulose samples using solid-state C-13 NMR was demonstrated. This method can serve as a primary standard to calibrate other methods for molar-mass determination in hydrolyzed cellulose.
Article
Biochemistry & Molecular Biology
D. Pawcenis, M. Lesniak, M. Szumera, M. Sitarz, J. Profic-Paczkowska
Summary: Nanocelluloses have attracted much attention due to their mechanical properties, high surface area, and porosity. Sulfuric acid is commonly used for the production of cellulose nanocrystals, but it leads to cellulose esterification and lower thermal stability. Hydrochloric acid hydrolysis does not result in functionalization of the nanocellulose surface, but it lacks ionic interactions and causes poor colloidal stability. This study aimed to obtain stable aqueous suspensions of cellulose nanofibrils (CNF) through hydrochloric acid hydrolysis. The best stabilizing effect was achieved at pH 5-9 and with nonionic surfactants.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Peter G. Chiarelli, Jinru Chen, Ronald B. Pegg, Kevin Mis Solval
Summary: This study investigated the effect of demineralization on the physicochemical properties of hydrolyzed collagen from cannonball jellyfish. Demineralization significantly reduced mineral content and increased protein content, resulting in enhanced gelling and thickening properties of the gelatin powders. Gelatin solutions prepared with demineralized powders showed higher strength and viscosity. This study highlights the importance of demineralization in producing functional gelatin powders from cannonball jellyfish.
Review
Polymer Science
Solange Magalhaes, Catarina Fernandes, Jorge F. S. Pedrosa, Luis Alves, Bruno Medronho, Paulo J. T. Ferreira, Maria da Graca Rasteiro
Summary: Cellulose, the most abundant renewable polymer on Earth, can be obtained from various sources. Traditional fractionation methods involve harsh chemicals, but new sustainable processes have been developed. Cellulose and its derivatives have wide applications, particularly in textiles and packaging, as eco-friendly alternatives to synthetic materials. This review discusses cellulose's properties, green extraction methods, chemical modification, and applications of cellulose derivatives.
Article
Nutrition & Dietetics
Maysa Alves Rodrigues Brandao-Rangel, Carlos Rocha Oliveira, Fabiana Regina da Silva Olimpio, Flavio Aimbire, Jose Roberto Mateus-Silva, Felipe Augusto Chaluppe, Rodolfo P. Vieira
Summary: This study investigated the effects of collagen peptides on the proliferation and activation of fibroblasts and keratinocytes. The results showed that collagen peptides can promote cell proliferation and reduce inflammatory responses caused by lipopolysaccharide.
Article
Chemistry, Multidisciplinary
Helal Abujubara, Jie Yang, A. Birsen Otyakmaz, Anais F. M. Noisier, Werngard Czechtizky, Malin Lemurell, Alesia A. A. Tietze
Summary: We report a mild ionic liquid (IL)-mediated thiolation technique using 1,3-ethyl-methyl imidazolium acetate as a solvent and precursor to generate activated IL for the conjugation reaction of small molecules and peptides. Interestingly, a bifunctional active IL could also be successfully employed as a linker for peptides lacking cysteine. This study lays the foundation for further investigation of the use of active ILs in modifying larger and more complex therapeutic modalities.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Farid Torabizadeh, Milad Fadaie, Esmaeil Mirzaei, Shaghayegh Sadeghi, Gholam-Reza Nejabat
Summary: This study compared the physical properties and cellular performance of physically cross-linked collagen hydrogel reinforced with cellulose nanocrystals (CNCs) and cellulose nanofibrils (CNFs). The results showed that the addition of nanofillers improved the mechanical properties of the hydrogel and had different effects on cell viability and morphology.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Pantitra Yakaew, Thapani Phetchara, Piyaporn Kampeerapappun, Kawee Srikulkit
Summary: SCOBY bacterial cellulose (BC) and hydrolyzed collagen (HC) blend films coated with chitosan showed improved antimicrobial activity and balanced loading/releasing performance of ascorbic acid. The blend films could maintain active ascorbic acid for a long time by controlling water swellability and blending formulation.
Article
Materials Science, Paper & Wood
Jaideep Adhikari, Shalini Dasgupta, Ananya Barui, Manojit Ghosh, Prosenjit Saha
Summary: A macromolecular approach using collagen and functionalized bacterial cellulose (f-BC) was proposed for tissue engineering, which showed improved cell adhesion and acceptable degradation profile. The pure bacterial cellulose (BC) was functionalized through four different chemical routes, and the successful functionalization was confirmed using various characterization techniques. The scaffolds exhibited nano fibrous surface morphology and satisfactory porosity, surface area, hydrophilicity, degradation profile, and buffer uptake ability for tissue engineering applications. The f-BC/collagen composite, prepared by treating f-BC with amine or (2,2,6,6-tetramethylpiperidin-1-yl)oxyl and crosslinking with collagen and genipin, showed enhanced cell viability and non-toxicity.
Article
Chemistry, Multidisciplinary
Stefan Ioan Voicu, Vijay Kumar Thakur
Summary: Cellulose and its derivatives are among the most abundant sustainable polymers provided by nature, with a wide range of applications, but face limitations in functionalization due to the limited reactivity of hydroxyl groups. Aminopropyltriethoxysilane can serve as a versatile linker for functionalizing cellulose, with the remaining amino group offering higher reactivity and versatility, and has direct applicability in various reactive separation processes.
CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY
(2021)
Review
Dermatology
Roseane B. de Miranda, Patricia Weimer, Rochele C. Rossi
Summary: The supplementation of hydrolyzed collagen has shown significant positive effects on reducing skin aging, with a study concluding that ingestion for 90 days can reduce wrinkles and improve skin elasticity and hydration.
INTERNATIONAL JOURNAL OF DERMATOLOGY
(2021)
Article
Polymer Science
Nanticha Danmatam, John T. H. Pearce, Datchanee Pattavarakorn
Summary: Self-healable electroactive carboxymethyl cellulose/polythiophene/acid hydrolyzed cellulose (CMC/PTh/AHC) hydrogels were fabricated and investigated for their electro-responsive and self-healing performances.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Kaixuan Zhao, Xiaojing Tian, Jinfeng Xing, Na Huang, Hongjie Zhang, Huanying Zhao, Wenhang Wang
Summary: Collagen films were reinforced with celluloses of different geometries, resulting in improved mechanical properties. Cellulose nanofibers effectively bore stress through intercrystalline fracture, while interfibrillar slippage and pull-off of cellulosic fines increased toughness. Microcrystalline cellulose and cellulose nanocrystals weakened the films' mechanical behavior. The effects of cellulose geometries on various properties of films were also investigated.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Multidisciplinary
Xia Sun, Yeling Zhu, Jiaying Zhu, Katherine Le, Peyman Servati, Feng Jiang
Summary: The authors propose a green and sustainable method to fabricate cellulose-based ion conductors with high stretchability, toughness, transparency, and self-healing ability. The obtained ion conductors demonstrate good long-term performance stability after 1 month storage.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Review
Engineering, Environmental
M. Mehedi Hasan Rocky, Ismail M. M. Rahman, Foni B. Biswas, Shafiqur Rahman, Masaru Endo, Kuo H. Wong, Asami S. Mashio, Hiroshi Hasegawa
Summary: This review summarizes recent advances in cellulose-based adsorbents for water and wastewater treatment, highlighting surface functionalization and potential applications. The introduction of surface functional groups through chemical modification techniques significantly improves the adsorption properties and selectivity of cellulose-based adsorbents towards metallic species. The potential of blended adsorbents and cellulosic biomaterials with varying cellulose contents as metal sorbents are also discussed. Current research trends, gaps, challenges, and future perspectives in this field are identified.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Environmental Sciences
Tamires Minucelli, Renato Marcio Ribeiro-Viana, Dionisio Borsato, Galdino Andrade, Martha Viviana Torres Cely, Marcos Roberto de Oliveira, Cristiani Baldo, Maria Antonia Pedrine Colabone Celligoi
WASTE AND BIOMASS VALORIZATION
(2017)
Article
Biochemistry & Molecular Biology
Sabrina Alves de Oliveira, Bruno Campos da Silva, Izabel Cristina Riegel-Vidotti, Alexandre Urbano, Paula Cristina de Sousa Faria-Tischer, Cesar Augusto Tischer
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2017)
Article
Materials Science, Biomaterials
Simone Birkheur, Paula Cristina de Sousa Faria-Tischer, Cesar A. Tischer, Elisangela Flavia Pimentel, Marcio Fronza, Denise Coutinho Endringer, Anna Paola Butera, Renato Marcio Ribeiro-Viana
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2017)
Article
Chemistry, Organic
Benedetta Bertolotti, Ieva Sutkeviciute, Martino Ambrosini, Renato Ribeiro-Viana, Javier Rojo, Franck Fieschi, Hana Dvorakova, Martina Kasakova, Kamil Parkan, Martina Hlavackova, Katerina Novakova, Jitka Moravcova
ORGANIC & BIOMOLECULAR CHEMISTRY
(2017)
Article
Materials Science, Biomaterials
Antonio Munoz, Beatriz M. Illescas, Joanna Luczkowiak, Fatima Lasala, Renato Ribeiro-Viana, Javier Rojo, Rafael Delgado, Nazario Martin
JOURNAL OF MATERIALS CHEMISTRY B
(2017)
Article
Biology
Francielle Lina Vidotto, Geovana Piveta Ribeiro, Cesar Augusto Tischer
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Samara M. A. Alexandre, Maria L. Corradi da Silva, Ana F. D. Vasconcelos, Diego T. D. Exposti, Cesar A. Tischer, Alicia Prieto, Dolores Diaz, Ramon Kaneno
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2018)
Article
Chemistry, Inorganic & Nuclear
Leonardo C. Moraes, Gilmar P. de Souza, Humberto Fajardo, Sulusmon C. Luz, Eleuterio Alvarez, Francesc Lloret, Renato M. Ribeiro-Viana, Javier Rojo, Humberto O. Stumpf, Rute C. Figueiredo, Rodrigo S. Correa
INORGANICA CHIMICA ACTA
(2019)
Article
Pharmacology & Pharmacy
Daniel Silqueira Martins Guimaraes, Leticia Silveira de Sousa Luz, Sara Batista do Nascimento, Lorena Rabelo Silva, Natalia Rezende de Miranda Martins, Heloisa Goncalves de Almeida, Vitoria de Souza Reis, Sarah El Chamy Maluf, Alexandre Budu, Juliane Aparecida Marinho, Clarice Abramo, Adriana Karaoglanovic Carmona, Marina Goulart da Silva, Gisele Rodrigues da Silva, Victor Matheus Kemmer, Anna Paola Butera, Renato Marcio Ribeiro-Viana, Marcos Leoni Gazarini, Clebio Soares Nascimento Junior, Luciana Guimaraes, Fabio Vieira dos Santos, Whocely Victor de Castro, Gustavo Henrique Ribeiro Viana, Cristiana Ferreira Alves de Brno, Fernando de Pilla Varotti
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2019)
Article
Biochemistry & Molecular Biology
Khamis Youssef, Admilton G. de Oliveira, Cesar Augusto Tischer, Ibrar Hussain, Sergio Ruffo Roberto
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2019)
Article
Biotechnology & Applied Microbiology
A. Magri, M. R. Oliveira, C. Baldo, C. A. Tischer, D. Sartori, M. S. Mantovani, M. A. P. C. Celligoi
JOURNAL OF APPLIED MICROBIOLOGY
(2020)
Article
Environmental Sciences
Karen Stefany Conceicao, Mayara de Alencar Almeida, Isadora Caroline Sawoniuk, Gabriela Dornelas Marques, Paula Cristina de Sousa Faria-Tischer, Cesar Augusto Tischer, Josiane Alessandra Vignoli, Doumit Camilios-Neto
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2020)
Article
Polymer Science
Katlyn Bazoli dos Santos, Gustavo Eiji Higawa, Karen Stefany Conceicao, Denise Coutinho Endringer, Elisangela Flavia Pimentel Schmitt, Lorena Martins Xavier, Marcio Fronza, Alessandra Stevanato, Cesar Augusto Tischer, Renato Marcio Ribeiro-Viana
Summary: This study describes the synthesis of small hydrophobic molecules based on inexpensive alcohols conjugated to bacterial cellulose, which enhances the hydrophobicity and antimicrobial activity of the films while maintaining cytocompatibility. The modified cellulose films show potential in preparing dressings with improved properties based on bacterial cellulose.
MACROMOLECULAR RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Camila de Souza Barbosa, Daniel Silqueira Martins Guimaraes, Alessandra Mirtes Marques Neves Goncalves, Maria Cristina da Silva Barbosa, Marilia Ladeira Alves e Costa, Clebio Soares Nascimento Junior, Luciana Guimaraes, Renato Marcio Ribeiro-Viana, Fabio Vieira dos Santos, Cristiana Ferreira Alves de Brito, Fernando de Pilla Varotti, Gustavo Henrique Ribeiro Viana
Article
Materials Science, Multidisciplinary
Simone Birkheur, Edson Laureto, Ricardo Vignoto Fernandes, Cesar Tischer, Anna Paola Butera, Renato M. Ribeiro-Viana
MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS
(2020)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)