Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

(2018) Ana Mendanha Falcão et al.   NATURE MEDICINE

Metabolites predict lesion formation and severity in relapsing-remitting multiple sclerosis

(2017) Antoine M Klauser et al.   Multiple Sclerosis Journal

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival

(2017) Eleni Kougioumtzidou et al.   eLife

Metabolites predict lesion formation and severity in relapsing-remitting multiple sclerosis

(2017) Antoine M Klauser et al.   Multiple Sclerosis Journal

Ionotropic glutamate receptor expression in human white matter

(2016) Pia Crone Christensen et al.   NEUROSCIENCE LETTERS

Inhibition of SystemXc−Transporter Attenuates Autoimmune Inflammatory Demyelination

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Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors

(2015) Hélène O. B. Gautier et al.   Nature Communications

In vivo evidence of glutamate toxicity in multiple sclerosis

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Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models

(2013) Amanda Boyd et al.   ACTA NEUROPATHOLOGICA

Oligodendrocyte-microglia cross-talk in the central nervous system

(2013) Laura Peferoen et al.   IMMUNOLOGY

Disruption of NMDA Receptors in Oligodendroglial Lineage Cells Does Not Alter Their Susceptibility to Experimental Autoimmune Encephalomyelitis or Their Normal Development

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Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

System xc- cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS

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Increased expression of cystine/glutamate antiporter in multiple sclerosis

(2011) Olatz Pampliega et al.   Journal of Neuroinflammation

Inflammatory Cortical Demyelination in Early Multiple Sclerosis

(2011) Claudia F. Lucchinetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Excitatory Glycine Responses of CNS Myelin Mediated by NR1/NR3 "NMDA" Receptor Subunits

(2010) J. C. Pina-Crespo et al.   JOURNAL OF NEUROSCIENCE

Dysmyelinated axons in shiverer mice are highly vulnerable to α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated toxicity

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Effects of glutamate receptor activation on NG2-glia in the rat optic nerve

(2009) Nicola Hamilton et al.   JOURNAL OF ANATOMY

Regulation of Glutamate Transport in Developing Rat Oligodendrocytes

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Association of an EAAT2 polymorphism with higher glutamate concentration in relapsing multiple sclerosis

(2008) Olatz Pampliega et al.   JOURNAL OF NEUROIMMUNOLOGY

NMDA Receptor Blockade with Memantine Attenuates White Matter Injury in a Rat Model of Periventricular Leukomalacia

(2008) S. M. Manning et al.   JOURNAL OF NEUROSCIENCE

Expression of glutamate transporters GLT-1 and GLAST in different regions of rat brain during the course of experimental autoimmune encephalomyelitis

(2008) K. Mitosek-Szewczyk et al.   NEUROSCIENCE

Glutamate Receptor Expression in Multiple Sclerosis Lesions

(2007) Jia Newcombe et al.   BRAIN PATHOLOGY