4.5 Review

MiR-326: Promising Biomarker for Cancer

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CANCER MANAGEMENT AND RESEARCH
卷 11, 期 -, 页码 10411-10418

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DOVE MEDICAL PRESS LTD
DOI: 10.2147/CMAR.S223875

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MicroRNA; miR-326; tumor suppressor; cancer; metastasis; oncogene

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MicroRNAs (miRNAs) are small non-coding and highly conserved RNAs that act in biological processes including cell proliferation, invasion, apoptosis, metabolism, signal transduction, and tumorigenesis. The previously identified miRNA-326 (miR-326) has been reported to participate in cellular apoptosis, tumor growth, cell invasion, embryonic development, immunomodulation, chemotherapy resistance, and oncogenesis. This review presents a detailed overview of what is known about the effects of miR-326 on cell invasion, metastasis, drug resistance, proliferation, apoptosis, and its involvement in signaling pathways.

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