Article
Materials Science, Multidisciplinary
Haoxuan Li, Paulo S. Branicio
Summary: In this study, ultralow friction of graphene-coated silica nanoparticle films on diamond surfaces is demonstrated using molecular dynamics simulations. The coated structure combines the low friction coefficient of C-720 fullerenes with the nanobearing capability of silica nanoparticles, resulting in ultralow friction and high compressive strength. This technology has the potential to enhance reliability, extend the working life, and reduce energy requirements of machines and devices.
COMPUTATIONAL MATERIALS SCIENCE
(2022)
Article
Chemistry, Physical
Jannatun Nayeem, Md Abdul Alim Al-Bari, Md Mahiuddin, Md Abdur Rahman, Olin Thompson Mefford, Hasan Ahmad, Md Mahbubor Rahman
Summary: In this study, a new approach was developed to improve the stability of iron oxide nanoparticles (IONPs) and their interactions with drug molecules by surface modification with poly[N-isopropylacrylamide-co-(3-acrylamidopropyl) trimethylammonium chloride]. The resulting thermally sensitive magnetic nanocomposites (MNCs) showed promising potential for biomedical applications, as demonstrated by the successful immobilization of antibacterial vancomycin and inhibition of bacterial growth.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Biotechnology & Applied Microbiology
Hoonsub Kim, Pyung Won Im, Yuanzhe Piao
Summary: Uniform-sized iron oxide nanoparticles were encapsulated inside a silica shell using the reverse microemulsion technique, then transformed into iron nitride through thermal treatment under NH3. The resulting core/shell nanostructures exhibited high uniformity in particle-size distribution. The acid-resistant properties of the iron nitride at silica core/shell nanostructures were significantly higher than the starting iron oxide at silica.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Zhongtao Li, Jing Guo, Mengmeng Zhang, Guohua Li, Liguo Hao
Summary: Magnetic resonance molecular imaging can provide anatomical, functional, and molecular information. This study presents a novel T-1 contrast agent, Gd2O3@MSN, which utilizes gadolinium-doped mesoporous silica nanoparticles for magnetic imaging. The results show that Gd2O3@MSN has a higher T-1 relaxivity, making it a potential candidate for in-vivo MRI contrast agents.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Physical
Mehri Karimi Jabali, Ali Reza Allafchian, Seyed Amir Hossein Jalali, Hamideh Shakeripour, Rezvan Mohammadinezhad, Fahime Rahmani
Summary: The study introduces the use of ascorbic acid-modified chitosan as a pDNA nanocarrier, demonstrating promising pDNA release in intestinal fluids and potential biocompatibility with cell lines Vero and EPC. Chitosan effectively shields pDNA in gastric environments and allows for release in alkaline intestinal tissues, presenting a novel approach for gene delivery through oral administration.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Energy & Fuels
Yuhang Jia, Daping Hu, Xue Wang, Haijuan Zhang, Pengcheng Du
Summary: Transition metal phosphides (TMPs) are widely used as electrode materials in supercapacitors (SCs) due to their adjustable electronic structure, variable composition, and excellent electrical conductivity. The incorporation of carbon materials can enhance the conductivity and electrochemical properties of TMPs. In this study, a carbon layer coated Ni2P nanoparticles embedded in a threedimensional graphene network (Ni2P@C@rGO) was designed and showed excellent capacitance and cycle stability, making it a promising candidate for high-performance energy storage devices.
JOURNAL OF ENERGY STORAGE
(2022)
Article
Engineering, Environmental
Mahan Ghazi, Sajjad Janfaza, Hamed Tahmooressi, Nishat Tasnim, Mina Hoorfar
Summary: This study focuses on improving the selectivity of microfluidic gas sensors for detecting a range of VOCs by adding micro- and nanofeatures to the microchannel. The results show an average improvement of 64.4% and 120.9% in sensor selectivity with microfeatures and both nano- and microfeatures, respectively. Characterization of the nano- and microfeatures was done through SEM, XPS, and water contact angle measurement.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Gilbert Aaron Lee, Wan-Li Lin, Duen-Pang Kuo, Yi-Tien Li, Yu-Wei Chang, Yung-Chie Chen, Shiu-Wen Huang, Justin Bo-Kai Hsu, Cheng-Yu Chen
Summary: Lipid-coated SPIO nanoparticles conjugated with PD-L1 antibodies can specifically target PD-L1 expression in glioblastoma, including temozolomide-resistant cases, as demonstrated in this study through characterizations such as dynamic light scattering and in vivo T2* map MRI analysis. This approach shows promise for early diagnosis and predicting responses to targeted PD-L1 immunotherapy in glioblastoma patients.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Maria Salvador, Gemma Gutierrez, Sara Noriega, Amanda Moyano, Maria Carmen Blanco-Lopez, Maria Matos
Summary: Superparamagnetic magnetite nanoparticles with narrow size distribution have been successfully synthesized through precipitation in water-in-oil microemulsion, showing great potential in medical and environmental applications. The optimization of washing protocol and their applicability in bioapplications have been demonstrated. These novel materials are useful for analytical applications requiring high sensitivity and interference removal, as shown in signal enhancement and magnetic separation tests.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Green & Sustainable Science & Technology
Maryam Farhana Kamel Ariffin, Ani Idris
Summary: Biocatalysis is a green technology that immobilizes enzymes onto magnetized nanomaterials, enhancing downstream processing and stability. The synthesized nanoparticles showed high tolerance to temperature and pH, while the immobilized lipase complex exhibited excellent catalytic activity. By applying this technology, efficient transesterification of palm oil to biodiesel can be achieved, meeting the general requirements for fuels.
Article
Physics, Applied
Yohannes W. Getahun, Felicia S. Manciu, Mark R. Pederson, Ahmed A. El-Gendy
Summary: Intensive studies have been conducted on graphene-based molecular magnets due to their exceptional electric, thermal, and mechanical properties. Aminoferrocene-based graphene system with room temperature superparamagnetic behavior in the long-range magnetic order has been introduced, showing colossal magnetocrystalline anisotropy comparable to or even larger than pure iron metal. The synthesis of aminoferrocene and its reaction with graphene oxide have been characterized and confirmed by various techniques. The behavior of aminoferrocene between hydroxylated graphene sheets has been modeled using density functional theory, suggesting potential applications in molecular magnets and quantum systems.
APPLIED PHYSICS LETTERS
(2023)
Article
Engineering, Chemical
Elif Demirel, Sakhavat Dadashov
Summary: In this study, silica-coated multi-walled carbon nanotubes were embedded in a pristine PVDF polymer matrix to develop a novel nanocomposite membrane. The addition of SiO2-CNTs improved permeability, increased rejection rate, and enhanced morphological properties, resulting in better filtration performance and increased membrane life.
CHEMICAL ENGINEERING COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Zeynep Dasdelen, Ayca Atilir Ozcan, Ali Ozcan
Summary: In this study, fumed silica, reduced graphene oxide, and their hybrid were tested as support materials for Au nanoparticles to prepare anode catalysts for sorbitol fuel cells. Among the different supports, Au@FS-rGO catalyst showed the highest current density for sorbitol oxidation, indicating a synergistic effect between FS and rGO.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Chemistry, Applied
Caiyun Xu, Ru Hu, Kaijie Li, Dong Liu, Yirui Ma, Hongbo Yu, Hongfeng Yin, Shenghu Zhou
Summary: In this work, a reverse microemulsion method is reported for synthesizing uniform and well-dispersed hollow porous silica nanospheres with metal (oxide) nanoparticles inside their cavities. The water phase consists of poly(ethylene imine) stabilized metal hydroxide nanoaggregates, which serve as void templates and deliver catalytic functionality into voids during silica deposition. The subsequent calcination produces hollow nanostructures and metal (oxide) nanoparticles within the central voids. This method is applicable to metals that have hydroxide precipitates under basic conditions and is suitable for most catalytically active metals. The catalytic efficiency of Pd@HPSNs for selective hydrogenation of phenylacetylene is demonstrated, with the enhancement attributed to the effect of void confinement.
MICROPOROUS AND MESOPOROUS MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Mehrdad Akrami, Seyed Mohsen Dehnavi, Mahdi Barjasteh, Mehdi Jahanfar
Summary: Fe3O4/graphene oxide (Fe3O4/GO) and Fe3O4/polypyrrole/graphene oxide (Fe3O4/PPy/GO) magnetic nanocomposites were successfully synthesized for DNA isolation. The aminated nanocomposites exhibited excellent DNA isolation performance. The adsorption equilibrium data fit well with the Freundlich isotherm, while the kinetic outcomes followed the pseudo-second-order model. Electrophoresis confirmed the effectiveness of the nanocomposites for DNA adsorption/desorption. Furthermore, the Fe3O4/PPy/GO nanocomposites maintained high isolation ability after five cycles, with only a slight reduction in adsorption capacity (8.9%). The MTT assay demonstrated that the nanocomposites were non-toxic and biocompatible, making them suitable for DNA isolation in biological applications.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Islam Seder, Ahla Jo, Bong-Hyun Jun, Sung-Jin Kim
Summary: In this study, a microfluidic platform is presented for the simple, automated, and highly sensitive immunoassay of viral antigens. By utilizing the motion of the layers and the surface tension in the liquids, reagents are able to mix homogeneously between the top and bottom chambers. The automated device achieves a highly sensitive magnetic bead-based sandwich immunoassay for the influenza A H1N1 virus within 32.5 min using magnetic beads and quantum dots.
Article
Chemistry, Multidisciplinary
Sungje Bock, Hyung-Mo Kim, Jaehi Kim, Jaehyun An, Yun-Sik Choi, Xuan-Hung Pham, Ahla Jo, Kyeong-min Ham, Hobeom Song, Jung-Won Kim, Eunil Hahm, Won-Yeop Rho, Sang Hun Lee, Seung-min Park, Sangchul Lee, Dae Hong Jeong, Ho-Young Lee, Bong-Hyun Jun
Summary: A highly sensitive LFIA kit using QD-embedded silica nanoparticles was developed for the diagnosis of prostate cancer, which can be conducted through a smartphone and image processing software.
Article
Biochemistry & Molecular Biology
Xuan-Hung Pham, Van-Khue Tran, Eunil Hahm, Yoon-Hee Kim, Jaehi Kim, Wooyeon Kim, Bong-Hyun Jun
Summary: This study reports a novel method for preparing bimetallic nanoparticles with high activity using seed-mediated growth on a silica core template. The resulting nanoparticles exhibit excellent peroxidase-like nanozyme activity and high sensitivity for H2O2 detection.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Analytical
Islam Seder, Kyeong-Min Ham, Bong-Hyun Jun, Sung-Jin Kim
Summary: This study presents a fluidic dispensing system that can automate the sequential delivery of multiple reagents for lateral flow assays. The platform provides accurate fluidic timing control, minimal reagent loss, and no reagent overlap or carryover. It enables high sensitivity solution-based assays in a short period of time.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Kyeong-Min Ham, Minhee Kim, Sungje Bock, Jaehi Kim, Wooyeon Kim, Heung Su Jung, Jaehyun An, Hobeom Song, Jung-Won Kim, Hyung-Mo Kim, Won-Yeop Rho, Sang Hun Lee, Seung-Min Park, Dong-Eun Kim, Bong-Hyun Jun
Summary: A Cd-free quantum dot nanoprobe for bioimaging was fabricated by embedding multiple indium phosphide/zinc sulfide quantum dots onto silica templates and coating them with a silica shell. The resulting nanoparticles exhibited excellent optical properties and hydrophilicity, and showed prominent fluorescence signals in tumors, demonstrating their potential for bioimaging applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Editorial Material
Chemistry, Multidisciplinary
Seung-Min Park, Bong-Hyun Jun
Editorial Material
Biochemistry & Molecular Biology
Won-Yeop Rho, Bong-Hyun Jun
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Jaehi Kim, Min-Sup Shin, Jonghyun Shin, Hyung-Mo Kim, Xuan-Hung Pham, Seung-min Park, Dong-Eun Kim, Young Jun Kim, Bong-Hyun Jun
Summary: Rapid, accurate, and convenient diagnosis is crucial for effective disease management, and lateral flow immunoassay (LFIA) with optical nanoparticles (NPs) has emerged as a major diagnostic tool. Researchers have developed various types of optical NPs with modified optical properties to serve as probes for LFIA. This review focuses on the literature about LFIA with optical NPs for specific target detection in diagnostics.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Editorial Material
Biochemistry & Molecular Biology
Bong-Hyun Jun
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Eunbin Cho, Jayoung Namgung, Jong Sam Lee, Jinmin Jang, Bong-Hyun Jun, Dong-Eun Kim
Summary: Researchers have developed a simple method using mesoporous silica particles as RNA adsorbents to remove double-stranded RNA (dsRNA) impurities from synthesized RNA. Among various polyamines tested, spermidine showed superior capability of RNA binding to the silica matrix. By adjusting the EDTA concentration, at least 80% of the dsRNA can be removed from the mesoporous silica-adsorbed RNA. Compared to cellulose-based methods, using mesoporous silica particles with spermidine and EDTA for binding and elution, respectively, demonstrated more effective removal of dsRNA contaminants from synthesized RNA.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Eunil Hahm, Ahla Jo, Eunji Kang, Kwanghee Yoo, Minsup Shin, Jaehyun An, Xuanhung Pham, Hyungmo Kim, Homan Kang, Jaehi Kim, Bonghyun Jun
Summary: In this study, a generally applicable silica encapsulation method using TMPS was developed for non-hydrophilic optical nanoparticles, such as quantum dots and gold nanoparticles, to enhance their biocompatibility and stability. The fabricated silica-encapsulated nanoparticles showed optical properties without significant changes in the quantum yield or Raman signal intensity.
Article
Biochemistry & Molecular Biology
Jaehi Kim, Sunray Lee, Yeon Kyung Lee, Bomi Seong, Hyung-Mo Kim, San Kyeong, Wooyeon Kim, Kyeongmin Ham, Xuan-Hung Pham, Eunil Hahm, Ji Yeon Mun, Mukhtar Anthony Safaa, Yoon-Sik Lee, Bong-Hyun Jun, Hyun-Sook Park
Summary: This study presents an improved single-particle tracking (SPT) method using silica-coated QD-embedded silica nanoparticles (QD(2)). QD(2) exhibits brighter fluorescence and lower toxicity compared to single quantum dots, allowing long-term intracellular tracking. These findings suggest that QD(2) can serve as a substitute for traditional organic fluorophores or single quantum dots in SPT.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)