Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation

Sepsis – thoughtful management for the non-expert

(2018) Robert Tidswell et al.   CLINICAL MEDICINE

Nitric oxide synthase 2 enhances the survival of mice during Salmonella Typhimurium infection-induced sepsis by increasing reactive oxygen species, inflammatory cytokines and recruitment of neutrophils to the peritoneal cavity

(2018) Shikha Yadav et al.   FREE RADICAL BIOLOGY AND MEDICINE

Knockout of Toll-like receptor 4 improves survival and cardiac function in a murine model of severe sepsis

(2018) Dan Zhou et al.   Molecular Medicine Reports

Procalcitonin: Usefulness in Acute Care Surgery and Trauma

(2018) Sara E. Parli et al.   Surgical Infections

Toll-like receptor 4–induced ryanodine receptor 2 oxidation and sarcoplasmic reticulum Ca2+leakage promote cardiac contractile dysfunction in sepsis

(2017) Jie Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biomarkers for diagnosis of neonatal sepsis: a literature review

(2017) Deepak Sharma et al.   Journal of Maternal-Fetal & Neonatal Medicine

Inhibition of PAI-1 Activity by Toddalolactone as a Mechanism for Promoting Blood Circulation and Removing Stasis by Chinese Herb Zanthoxylum nitidum var. tomentosum

(2017) Bo Yu et al.   Frontiers in Pharmacology

Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response

(2017) Yung-Li Hung et al.   Scientific Reports

Assessment of Clinical Criteria for Sepsis

(2016) Christopher W. Seymour et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sepsis-induced immune dysfunction: can immune therapies reduce mortality?

(2016) Matthew J. Delano et al.   JOURNAL OF CLINICAL INVESTIGATION

The diagnostic ability of procalcitonin and interleukin-6 to differentiate infectious from noninfectious systemic inflammatory response syndrome and to predict mortality

(2016) Mohd Basri Mat-Nor et al.   JOURNAL OF CRITICAL CARE

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

Procalcitonin testing to guide antibiotic therapy for the treatment of sepsis in intensive care settings and for suspected bacterial infection in emergency department settings: a systematic review and cost-effectiveness analysis

(2015) Marie Westwood et al.   HEALTH TECHNOLOGY ASSESSMENT

Is Procalcitonin-Guided Antimicrobial Use Cost-Effective in Adult Patients with Suspected Bacterial Infection and Sepsis?

(2015) Michelle Harrison et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Interferon-Gamma and Nitric Oxide Synthase 2 Mediate the Aggregation of Resident Adherent Peritoneal Exudate Cells: Implications for the Host Response to Pathogens

(2015) Bhagawat S. Chandrasekar et al.   PLoS One

JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

(2014) B. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Basis of NF-κB Signaling

(2013) Johanna Napetschnig et al.   Annual Review of Biophysics

Procalcitonin as a diagnostic marker and IL-6 as a prognostic marker for sepsis

(2013) Dong Wook Jekarl et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Nitric-oxide Synthase-2 Linkage to Focal Adhesion Kinase in Neutrophils Influences Enzyme Activity and β2Integrin Function

(2013) Stephen R. Thom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View

(2013) Wibke Schulte et al.   MEDIATORS OF INFLAMMATION

Severe sepsis and septic shock

(2013) Christa A Schorr et al.   Virulence

Regulation of HMGB1 release by inflammasomes

(2013) Ben Lu et al.   Protein & Cell

Usefulness of procalcitonin clearance as a prognostic biomarker in septic shock. A prospective pilot study

(2012) J.C. Ruiz-Rodríguez et al.   Medicina Intensiva

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

HMGB1, a potent proinflammatory cytokine in sepsis

(2010) Wenchang Huang et al.   CYTOKINE

The zinc finger domain of IKKγ (NEMO) protein in health and disease

(2010) Amde Selassie Shifera   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia

(2010) M. Lamkanfi et al.   JOURNAL OF IMMUNOLOGY

Serum procalcitonin at the time of admission to the ICU as a predictor of short-term mortality

(2009) Fan-Su Meng et al.   CLINICAL BIOCHEMISTRY