Article
Environmental Sciences
Peien Zhou, Wangjian Zhang, Yu-Jie Xu, Ru-Qing Liu, Zhengmin Qian, Stephen Edward McMillin, Elizabeth Bingheim, Li-Zi Lin, Xiao-Wen Zeng, Bo-Yi Yang, Li-Wen Hu, Wen Chen, Gongbo Chen, Yunjiang Yu, Guang-Hui Dong
Summary: The study found that long-term exposure to ozone may be associated with an increased risk of attention-deficit/hyperactivity disorder (ADHD) among children. After adjusting for covariates, each increase in ozone concentration was linked to a higher risk of ADHD, ADHD-T, and ADHP. Furthermore, longer exercise time and breastfeeding may reduce the risk of ADHD.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Ling Qi, Anqi Fu, Xiaoli Duan
Summary: The World Health Organization has updated the target for annual mean NO2 based on new evidence, and a study estimates the excess deaths associated with long-term exposure to NO2 in China. The study found varying effects on different diseases and suggests that reducing NO2 emissions can offset the adverse effects of population growth and aging.
ENVIRONMENTAL RESEARCH LETTERS
(2022)
Review
Environmental Sciences
Xiaojing Zhu, Bingqian Liu, Chen Guo, Zhigang Li, Miaomiao Cheng, Xiaoyan Zhu, Yongjie Wei
Summary: Black carbon (BC) is a byproduct of incomplete or inefficient combustion and is associated with various adverse health effects. This study analyzed the relationship between BC exposure and different mortalities, both short-term and long-term. The review included 29 articles that met the eligibility criteria, with positive associations found between BC and total mortality, as well as cause-specific disease mortalities. The study suggests that BC has a higher impact on respiratory health than cardiovascular health, and further research is needed to consider BC as a separate pollutant.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Laure Gayraud, Marion Mortamais, Cedric Schweitzer, Kees de Hoogh, Audrey Cougnard-Gregoire, Jean-Francois Korobelnik, Marie-Noelle Delyfer, Marie-Benedicte Rougier, Karen Leffondre, Catherine Helmer, Danielle Vienneau, Claudine Berr, Cecile Delcourt
Summary: Chronic exposure to air pollution, particularly fine particulate matter (PM2.5) and black carbon (BC), is associated with faster thinning of the retinal nerve fiber layer (RNFL) in individuals with glaucoma. This study highlights the importance of considering air pollution as a potential risk factor for neurodegenerative diseases.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Zhennan Lin, Shufeng Chen, Fangchao Liu, Jianxin Li, Jie Cao, Keyong Huang, Fengchao Liang, Jichun Chen, Hongfan Li, Jianfeng Huang, Dongsheng Hu, Chong Shen, Yingxin Zhao, Xiaoqing Liu, Ling Yu, Xiangfeng Lu, Dongfeng Gu
Summary: Long-term exposure to high levels of PM2.5 is associated with increased blood pressure and hypertension risk. In China, for each 10μg/m3 increase in PM2.5 concentration, systolic and diastolic blood pressure increased by 1.67mmHg and 0.45mmHg, respectively, and the prevalence of hypertension increased by 29%. The relationship between PM2.5 and blood pressure may be non-linear.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Garam Byun, Yongsoo Choi, Sera Kim, Jong-Tae Lee
Summary: This study investigated the association between long-term exposure to ambient ozone and mortality in South Korea, using different exposure metrics. The results showed heterogeneous effect estimates for different ozone exposure metrics, and suggested that year-round 24-h average ozone can be considered as an alternative long-term standard for ozone.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Xiaoyu Hou, Zhenxing Mao, Xiaoqin Song, Ruiying Li, Wei Liao, Ning Kang, Caiyun Zhang, Xiaotian Liu, Ruoling Chen, Wenqian Huo, Chongjian Wang, Jian Hou
Summary: This study examines the association between exposure to cooking fuel type and ambient ozone levels, and hepatic fibrosis indices among rural adults. The findings suggest that solid fuel users, particularly women with high ozone exposure, have an increased risk of hepatic fibrosis.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Environmental Sciences
Sofia Zafeiratou, Evangelia Samoli, Konstantina Dimakopoulou, Sophia Rodopoulou, Antonis Analitis, Antonio Gasparrini, Massimo Stafoggia, Francesca De' Donato, Shilpa Rao, Ana Monteiro, Masna Rai, Siqi Zhang, Susanne Breitner, Kristin Aunan, Alexandra Schneider, Klea Katsouyanni
Summary: The study found that long-term exposure to extreme temperatures is associated with increased total and cardiovascular disease mortality and morbidity. Cardiovascular and respiratory risks are related to temperature, with stronger effects on the elderly and socially deprived populations. Further research is needed to investigate the long-term effects of temperature extremes and their impact on different population groups.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Marnie F. Hazlehurst, Logan C. Dearborn, Allison R. Sherris, Christine T. Loftus, Margaret A. Adgent, Adam A. Szpiro, Yu Ni, Drew B. Day, Joel D. Kaufman, Neeta Thakur, Rosalind J. Wright, Sheela Sathyanarayana, Kecia N. Carroll, Paul E. Moore, Catherine J. Karr
Summary: This study aimed to investigate the impact of ozone exposure from birth to age 8 on lung function in middle childhood. The results showed that there were no adverse associations between ozone exposure and lung function in children with low ozone concentrations.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Ruiying Li, Gongbo Chen, Mingming Pan, Xiaoyu Hou, Ning Kang, Ruoling Chen, Yinghao Yuchi, Wei Liao, Xiaotian Liu, Zhenxing Mao, Wenqian Huo, Yuming Guo, Shanshan Li, Chongjian Wang, Jian Hou
Summary: Long-term exposure to high concentrations of ambient ozone and low residential greenness is associated with decreased molecular biomarkers of aging. Increased residential greenness may attenuate the adverse effects of ambient ozone exposure on aging.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Medicine, General & Internal
Xinye Qiu, Liuhua Shi, Laura D. Kubzansky, Yaguang Wei, Edgar Castro, Haomin Li, Marc G. Weisskopf, Joel D. Schwartz
Summary: This study found statistically significant harmful associations between long-term exposure to common levels of air pollution and increased risk of depression diagnosis after age 64 years among older adults in the US. The study suggests that air pollution is a potential risk factor for late-onset depression.
Article
Endocrinology & Metabolism
Jialong Wu, Bing Guo, Han Guan, Fei Mi, Jingru Xu, Basang, Yajie Li, Haojiang Zuo, Lei Wang, Shiyu Feng, Jing Wei, Gongbo Chen, Shanshan Li, Yonglan Wei, Yuming Guo, Xing Zhao
Summary: This study found that long-term exposure to PM1, PM2.5, PM10, and NO2 was significantly associated with decreased bone strength in southwestern China adults. Additionally, populations with higher bone strength may be more susceptible to the adverse effects of air pollution.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Environmental Sciences
Neil Wright, Katherine Newell, Ka Hung Chan, Simon Gilbert, Alex Hacker, Yan Lu, Yu Guo, Pei Pei, Canqing Yu, Jun Lv, Junshi Chen, Liming Li, Om Kurmi, Zhengming Chen, Kin Bong Hubert Lam, Christiana Kartsonaki
Summary: Existing evidence on long-term ambient air pollution exposure and risk of cardio-respiratory diseases in China is mainly based on area average concentrations and fixed-site monitors, leading to uncertainty. This study used predicted local levels of air pollution to examine the relationship between exposure and risk.
ENVIRONMENTAL HEALTH
(2023)
Article
Engineering, Environmental
Xiyang Cai, Kaixuan Li, Xia Meng, Qinglin Song, Su Shi, Wenran Li, Yue Niu, Li Jin, Haidong Kan, Sijia Wang
Summary: This study is the first epigenome-wide association study on ozone exposure conducted in a large-scale Han Chinese cohort. The study identified DNA methylation changes on CpGs and regions, as well as related gene functions and pathways.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Environmental Sciences
Junjie Hu, Gongbo Chen, Shanshan Li, Yuming Guo, Junchao Duan, Zhiwei Sun
Summary: Epidemiological evidence shows that air pollutants are closely related to the occurrence and mortality of cardiovascular diseases. This study explored the association between long-term exposure to air pollutants and changes in cardiac function and structure in Chinese adults. The results showed that exposure to five pollutants (NO2, O3, PM1, PM2.5 and PM10) was associated with decreased left ventricular systolic function and increased pulses. Additionally, four pollutants were associated with decreased left ventricular diastolic parameters and increased cardiac structural parameter. Overall, chronic pollutant exposure is strongly associated with impaired left ventricular function in Chinese adults.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Clinical Neurology
Erin O. Semmens, Cindy S. Leary, Annette L. Fitzpatrick, Sindana D. Ilango, Christina Park, Claire E. Adam, Steven T. DeKosky, Oscar Lopez, Anjum Hajat, Joel D. Kaufman
Summary: This study found that long-term exposure to fine particulate matter (PM2.5) air pollution may increase the risk of dementia, particularly mixed vascular and Alzheimer's disease dementia.
ALZHEIMERS & DEMENTIA
(2023)
Article
Critical Care Medicine
Brigid A. Adviento, Elizabeth A. Regan, Barry J. Make, MeiLan K. Han, Marilyn G. Foreman, Anand S. Iyer, Surya P. Bhatt, Victor Kim, Jessica Bon, Xavier Soler, Gregory L. Kinney, Nicola A. Hanania, Katherine E. Lowe, Kristen E. Holm, Abebaw M. Yohannes, Gen Shinozaki, Karin F. Hoth, Jess G. Fiedorowicz
Summary: Studies have shown that there is an increased suicide risk associated with COPD and smoking. However, there have been no prospective studies examining suicide risk among individuals with smoking exposure along a spectrum of pulmonary diseases.
Article
Physiology
Charles R. Esther Jr, Wanda K. O'Neal, Neil E. Alexis, Abigail L. Koch, Christopher B. Cooper, Igor Barjaktarevic, Laura M. Raffield, Russel P. Bowler, Alejandro P. Comellas, Stephen P. Peters, Annette T. Hastie, Jeffrey L. Curtis, Bonnie Ronish, Victor E. Ortega, J. Michael Wells, Eitan Halper-Stromberg, Stephen I. Rennard, Richard C. Boucher
Summary: This study shows that nicotine and its metabolites can be detected in sputum supernatants and serve as biological markers of smoke exposure. The concentrations of nicotine in the airways of smokers remain elevated even when they have not smoked within 24 hours, suggesting a potential contribution to cigarette-induced airway disease.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
(2023)
Review
Clinical Neurology
Erin R. Kulick, Joel D. Kaufman, Coralynn Sack
Summary: Despite recent advances in treatment and prevention, stroke remains a leading cause of morbidity and mortality. A body of evidence suggests that elevated levels of ambient air pollutants may trigger cerebrovascular events in susceptible people and increase the risk of future events. This review assesses the evidence for both short and long-term exposure to ambient air pollution as a risk factor for stroke incidence and outcomes, and makes recommendations for mitigating exposure.
Letter
Peripheral Vascular Disease
Lyndia C. Brumback, Leah I. B. Andrews, David R. Jacobs, Daniel Duprez, Elizabeth K. Hom Thepaksorn, Joel D. Kaufman, Julie Denenberg, Matthew Allison
Article
Respiratory System
Mudiaga O. Sowho, Abigail L. Koch, Nirupama Putcha, Han Woo, Amanda Gassett, Laura M. Paulin, Kirsten Koehler, R. Graham Barr, Alejandro P. Comellas, Christopher B. Cooper, Igor Barjaktarevic, Michelle R. Zeidler, Martha E. Billings, Russell P. Bowler, MeiLan K. Han, Victor Kim, Robert Paine III, Trisha M. Parekh, Jerry A. Krishnan, Stephen P. Peters, Prescott G. Woodruff, Aaron M. Baugh, Joel D. Kaufman, David Couper, Nadia N. Hansel
Summary: This study examined the association between air pollution exposure, obesity, and sleep disturbances in individuals with chronic obstructive pulmonary disease (COPD). The results showed that overweight and obese COPD patients were more susceptible to the effects of ambient PM2.5 on sleep quality, while no association was found in lean/normal weight patients. This suggests that obesity and ambient PM2.5 may be modifiable risk factors for improving sleep quality in COPD.
CHRONIC OBSTRUCTIVE PULMONARY DISEASES-JOURNAL OF THE COPD FOUNDATION
(2023)
Article
Health Care Sciences & Services
Alpana Garg, Maran Subramain, Patrick B. Barlow, Lauren Garvin, Karin F. Hoth, Kimberly Dukes, Richard M. Hoffman, Alejandro P. Comellas
Summary: Post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PASC) is a complex condition with multisystem involvement. A survey was conducted to assess patients' experience at a PASC clinic, showing that most patients were satisfied with clinical services, with main symptoms including fatigue, brain fog, exercise intolerance, anxiety, sleep difficulties, and depression. Some patients scored significantly low in physical, mental, and cognitive domains. Strategies for optimizing recovery suggested by patients included continuity of care, a co-located multispecialty clinic, and timely information from emerging research. Participants appreciated the validation of symptoms and access to specialists provided by physicians.
JOURNAL OF PATIENT EXPERIENCE
(2023)
Letter
Critical Care Medicine
Alejandro P. Comellas, John D. Newell, Miranda Kirby, Jered P. Sieren, Sam Peterson, Charles Hatt, Craig J. Galban, Ella A. Kazerooni, David A. Lynch, MeiLan K. Han, Eric A. Hoffman
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Letter
Respiratory System
Motahareh Vameghestahbanati, Coralynn Sack, Artur Wysoczanski, Eric A. Hoffman, Elsa Angelini, Norrina B. Allen, Alain G. Bertoni, Junfeng Guo, David R. Jacobs Jr, Joel D. Kaufman, Andrew Laine, Ching-Long Lin, Daniel Malinsky, Erin D. Michos, Elizabeth C. Oelsner, Steven J. Shea, Karol E. Watson, Andrea Benedetti, R. Graham Barr, Benjamin M. Smith
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Physiology
Abhilash S. Kizhakke Puliyakote, Emma M. Stapleton, Kumar Durairaj, Kesavan Karuppusamy, Geetha B. Kathiresan, Kumaran Shanmugam, Sirajunnisa Abdul Rahim, Suresh Navaneethakrishnan, Monalisa Bilas, Rui Huang, Nervana Metwali, Matthew Jeronimo, Kung-Sik Chan, Junfeng Guo, Prashant Nagpal, Thomas M. Peters, Peter S. Thorne, Alejandro P. Comellas, Eric A. Hoffman
Summary: This study used quantitative computed tomography (qCT) to compare the lung function of women cooking with wood and liquified petroleum gas (LPG). The qCT results showed that women cooking with wood had more small airways disease, which may be related to inhaling biomass smoke. These findings are important for understanding the phenotypes of chronic lung disease and associated environmental lung pathologies in non-smoking women in the developing world.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Environmental Sciences
Sindana D. Ilango, Cindy S. Leary, Emily Ritchie, Erin O. Semmens, Christina Park, Annette L. Fitzpatrick, Joel D. Kaufman, Anjum Hajat
Summary: This study examined whether the social environment buffers the adverse effect of air pollution on dementia in older adults. The findings showed that long-term exposure to particulate matter and nitrogen dioxide increases the risk of dementia, but there was no evidence of additive interaction between air pollution and the social environment.
ENVIRONMENTAL EPIDEMIOLOGY
(2023)
Article
Critical Care Medicine
Amin Motahari, R. Graham Barr, MeiLan K. Han, Wayne H. Anderson, Igor Barjaktarevic, Eugene R. Bleecker, Alejandro P. Comellas, Christopher B. Cooper, David J. Couper, Nadia N. Hansel, Richard E. Kanner, Ella A. Kazerooni, David A. Lynch, Fernando J. Martinez, John D. Newell, Joyce D. Schroeder, Benjamin M. Smith, Prescott G. Woodruff, Eric A. Hoffman
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Editorial Material
Critical Care Medicine
Sean B. Fain, Alejandro P. Comellas
Article
Respiratory System
Siyang Zeng, Gang Luo, David A. Lynch, Russell P. Bowler, Mehrdad Arjomandi
Summary: Lung volumes can identify different pathological and physiological characteristics in susceptible smokers with early COPD and can predict the rate of disease progression and severity of symptoms.