Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

Endocardial Notch Signaling Promotes Cardiomyocyte Proliferation in the Regenerating Zebrafish Heart through Wnt Pathway Antagonism

(2019) Long Zhao et al.   Cell Reports

YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo

(2019) Tanner O. Monroe et al.   DEVELOPMENTAL CELL

Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration

(2018) Héctor Sánchez-Iranzo et al.   Nature Communications

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer

(2018) Subhamoy Dasgupta et al.   NATURE

Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration

(2018) Tobias Gerber et al.   SCIENCE

Yap is required for scar formation but not myocyte proliferation during heart regeneration in zebrafish

(2018) Michael A Flinn et al.   CARDIOVASCULAR RESEARCH

Profiling proliferative cells and their progeny in damaged murine hearts

(2018) Kai Kretzschmar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heart Regeneration in the Mexican Cavefish

(2018) William T. Stockdale et al.   Cell Reports

Hypoxia induces heart regeneration in adult mice

(2017) Yuji Nakada et al.   NATURE

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

(2017) Richard J. Mills et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opposite effects of Activin type 2 receptor ligands on cardiomyocyte proliferation during development and repair

(2017) Deepika Dogra et al.   Nature Communications

Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration

(2017) Shih-Lei Lai et al.   eLife

De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data

(2016) Dominic Grün et al.   Cell Stem Cell

Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State

(2016) Wen Gu et al.   Cell Stem Cell

Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration

(2016) Chi-Chung Wu et al.   DEVELOPMENTAL CELL

Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation

(2016) Ivan Menendez-Montes et al.   DEVELOPMENTAL CELL

Modulation of tissue repair by regeneration enhancer elements

(2016) Junsu Kang et al.   NATURE

Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury

(2016) Ge Tao et al.   NATURE

A Single-Cell Transcriptome Atlas of the Human Pancreas

(2016) Mauro J. Muraro et al.   Cell Systems

Dynamics of Cell Generation and Turnover in the Human Heart

(2015) Olaf Bergmann et al.   CELL

Functional Recovery of a Human Neonatal Heart After Severe Myocardial InfarctionNovelty and Significance

(2015) Bernhard J. Haubner et al.   CIRCULATION RESEARCH

Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart

(2015) Wataru Kimura et al.   NATURE

Single-cell messenger RNA sequencing reveals rare intestinal cell types

(2015) Dominic Grün et al.   NATURE

ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation

(2015) Gabriele D’Uva et al.   NATURE CELL BIOLOGY

Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window

(2015) Brian D. Polizzotti et al.   Science Translational Medicine

Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish

(2015) Matthew Gemberling et al.   eLife

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

(2014) Bao N. Puente et al.   CELL

High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation

(2014) D. W. Staudt et al.   DEVELOPMENT

c-kit+ cells minimally contribute cardiomyocytes to the heart

(2014) Jop H. van Berlo et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration

(2014) L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration

(2013) W.-Y. Choi et al.   DEVELOPMENT

Cellular network entropy as the energy potential in Waddington's differentiation landscape

(2013) Christopher R. S. Banerji et al.   Scientific Reports

A Zebrafish Model to Study and Therapeutically Manipulate Hypoxia Signaling in Tumorigenesis

(2012) Kirankumar Santhakumar et al.   CANCER RESEARCH

Hypoxia Induces Myocardial Regeneration in Zebrafish

(2012) Chris Jopling et al.   CIRCULATION

The regenerative capacity of the zebrafish heart is dependent on TGF  signaling

(2012) F. Chablais et al.   DEVELOPMENT

Mammalian heart renewal by pre-existing cardiomyocytes

(2012) Samuel E. Senyo et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Identification and Functional Characterization of Cardiac Pacemaker Cells in Zebrafish

(2012) Federico Tessadori et al.   PLoS One

The zebrafish heart regenerates after cryoinjury-induced myocardial infarction

(2011) Fabian Chablais et al.   BMC DEVELOPMENTAL BIOLOGY

Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming

(2011) Clifford D.L. Folmes et al.   Cell Metabolism

Rapid BAC selection for tol2-mediated transgenesis in zebrafish

(2011) J. Bussmann et al.   DEVELOPMENT

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish

(2011) J. M. Gonzalez-Rosa et al.   DEVELOPMENT

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

Regeneration of Cryoinjury Induced Necrotic Heart Lesions in Zebrafish Is Associated with Epicardial Activation and Cardiomyocyte Proliferation

(2011) Kristin Schnabel et al.   PLoS One

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

(2011) T. Heallen et al.   SCIENCE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Transcriptomics approach to investigate zebrafish heart regeneration

(2010) Eduard Sleep et al.   Journal of Cardiovascular Medicine

Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes

(2010) Kazu Kikuchi et al.   NATURE

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

Advances in understanding tissue regenerative capacity and mechanisms in animals

(2010) Kenneth D. Poss   NATURE REVIEWS GENETICS

Intraperitoneal Injection into Adult Zebrafish

(2010) Mary D. Kinkel et al.   Jove-Journal of Visualized Experiments

Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury

(2009) Kevin Bersell et al.   CELL

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

(2008) N. C. Chi et al.   GENES & DEVELOPMENT