Astragalus membranaceus–Derived Anti-Programmed Death-1 Monoclonal Antibodies with Immunomodulatory Therapeutic Effects against Tumors

Application of PD-1 Blockade in Cancer Immunotherapy

(2019) Xiaomo Wu et al.   Computational and Structural Biotechnology Journal

M2 macrophage infiltration into tumor islets leads to poor prognosis in non-small-cell lung cancer

(2019) Lili Cao et al.   Cancer Management and Research

Astragalus polysaccharides exerts anti-infective activity by inducing human cathelicidin antimicrobial peptide LL-37 in respiratory epithelial cells

(2018) Lin Zhao et al.   PHYTOTHERAPY RESEARCH

Anti-PD-1 therapy redirects macrophages from an M2 to an M1 phenotype inducing regression of OS lung metastases

(2018) Pooja Dhupkar et al.   Cancer Medicine

Astragalus membranaceus-Polysaccharides Ameliorates Obesity, Hepatic Steatosis, Neuroinflammation and Cognition Impairment without Affecting Amyloid Deposition in Metabolically Stressed APPswe/PS1dE9 Mice

(2017) Yung-Cheng Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bu Fei Decoction attenuates the tumor associated macrophage stimulated proliferation, migration, invasion and immunosuppression of non-small cell lung cancer, partially via IL-10 and PD-L1 regulation

(2017) Lina Pang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Emerging targets in cancer immunotherapy

(2017) Samantha Burugu et al.   SEMINARS IN CANCER BIOLOGY

Reprogramming of Tumor-Associated Macrophages with Anticancer Therapies: Radiotherapy versus Chemo- and Immunotherapies

(2017) Géraldine Genard et al.   Frontiers in Immunology

Astragalus membranaceus: A Review of its Protection Against Inflammation and Gastrointestinal Cancers

(2016) Kathy K. Auyeung et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Structural characterization of low molecular weight polysaccharide from Astragalus membranaceus and its immunologic enhancement in recombinant protein vaccine against systemic candidiasis

(2016) Fan Yang et al.   CARBOHYDRATE POLYMERS

Astragalus-containing Traditional Chinese Medicine, with and without prescription based on syndrome differentiation, combined with chemotherapy for advanced non-small-cell lung cancer: a systemic review and meta-analysis

(2016) S.F. Wang et al.   Current Oncology

Mechanism of action of ixabepilone and its interactions with the βIII-tubulin isotype

(2015) Manu Lopus et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy

(2015) S. P. Patel et al.   MOLECULAR CANCER THERAPEUTICS

Anti-PD-1-Targeted Therapies Focusing on Lymphatic Malignancies: Biological Rationale, Clinical Challenges and Opportunities

(2014) Meirav Kedmi et al.   ACTA HAEMATOLOGICA

Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models

(2013) Maria Jure-Kunkel et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

(2012) A. M. Gil-Bernabe et al.   BLOOD

Astragalus polysaccharide and sulfated epimedium polysaccharide synergistically resist the immunosuppression

(2012) Liwei Guo et al.   CARBOHYDRATE POLYMERS

Astragalus Polysaccharide Improves Palmitate-Induced Insulin Resistance by Inhibiting PTP1B and NF-κB in C2C12 Myotubes

(2012) Ming Zhao et al.   MOLECULES

Characterization of polysaccharide from Astragalus radix as the macrophage stimulator

(2011) Lu-Hang Zhao et al.   CELLULAR IMMUNOLOGY

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

(2010) V. Gocheva et al.   GENES & DEVELOPMENT

Astragalus polysaccharide and oxymatrine can synergistically improve the immune efficacy of Newcastle disease vaccine in chicken

(2010) Yuku Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synergy of Astragalus polysaccharides and probiotics (Lactobacillus and Bacillus cereus) on immunity and intestinal microbiota in chicks

(2009) S. P. Li et al.   POULTRY SCIENCE

HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

(2008) Rose Du et al.   CANCER CELL

Immunoregulatory and Anti-Tumor Effects of Polysaccharopeptide and Astragalus polysaccharides on Tumor-Bearing Mice

(2008) Li Jin et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Effects of Astragalus polysaccharides (APS) on the expression of immune response genes in head kidney, gill and spleen of the common carp, Cyprinus carpio L.

(2007) Chuntao Yuan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY