期刊
ANNUAL REVIEW OF ANIMAL BIOSCIENCES, VOL 8, 2020
卷 8, 期 -, 页码 25-45出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-animal-021419-083555
关键词
chromosomes; genome evolution; ancestral karyotype; genome sequencing
类别
资金
- Australian Research Council [DP160100187]
- National Science Foundation [1613806]
- Div Of Molecular and Cellular Bioscience
- Direct For Biological Sciences [1613806] Funding Source: National Science Foundation
Marsupial genomes, which are packaged into large chromosomes, provide a powerful resource for studying the mechanisms of genome evolution. The extensive and valuable body of work on marsupial cytogenetics, combined more recently with genome sequence data, has enabled prediction of the 2n = 14 karyotype ancestral to allmarsupial families. The application of both chromosome biology and genome sequencing, or chromosomics, has been a necessary approach for various aspects of mammalian genome evolution, such as understanding sex chromosome evolution and the origin and evolution of transmissible tumors in Tasmanian devils. The next phase of marsupial genome evolution research will employ chromosomics approaches to begin addressing fundamental questions in marsupial genome evolution and chromosome evolution more generally. The answers to these complex questions will impact our understanding across a broad range of fields, including the genetics of speciation, genome adaptation to environmental stressors, and species management.
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