Trends in mesenchymal stem cell clinical trials 2004‐2018: Is efficacy optimal in a narrow dose range?
出版年份 2019 全文链接
标题
Trends in mesenchymal stem cell clinical trials 2004‐2018: Is efficacy optimal in a narrow dose range?
作者
关键词
-
出版物
Stem Cells Translational Medicine
Volume 9, Issue 1, Pages 17-27
出版商
Wiley
发表日期
2019-12-05
DOI
10.1002/sctm.19-0202
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Challenges for mesenchymal stromal cell therapies
- (2019) Ivan Martin et al. Science Translational Medicine
- Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities
- (2018) Jacques Galipeau et al. Cell Stem Cell
- The promise of mesenchymal stem cell therapy for acute respiratory distress syndrome
- (2018) Ben Antebi et al. Journal of Trauma and Acute Care Surgery
- The “Growing” Reality of the Neurological Complications of Global “Stem Cell Tourism”
- (2018) Katie Julian et al. SEMINARS IN NEUROLOGY
- The promise of mesenchymal stem cell therapy for acute respiratory distress syndrome
- (2018) Ben Antebi et al. Journal of Trauma and Acute Care Surgery
- Immunomodulatory placental-expanded, mesenchymal stromal cells improve muscle function following hip arthroplasty
- (2018) Tobias Winkler et al. Journal of Cachexia Sarcopenia and Muscle
- Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty
- (2017) Samuel Golpanian et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial
- (2017) David C Hess et al. LANCET NEUROLOGY
- The first decade of advanced cell therapy clinical trials using perinatal cells (2005–2015)
- (2017) Pedro S Couto et al. Regenerative Medicine
- Concise Review: Mesenchymal Stem (Stromal) Cells: Biology and Preclinical Evidence for Therapeutic Potential for Organ Dysfunction Following Trauma or Sepsis
- (2017) Michael A. Matthay et al. STEM CELLS
- Clinical Trials with Mesenchymal Stem Cells: An Update
- (2016) Tiziana Squillaro et al. CELL TRANSPLANTATION
- Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic CardiomyopathyNovelty and Significance
- (2016) Javed Butler et al. CIRCULATION RESEARCH
- International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials
- (2016) Jacques Galipeau et al. CYTOTHERAPY
- Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)
- (2016) José M. Lamo-Espinosa et al. Journal of Translational Medicine
- Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial
- (2016) Julián Panés et al. LANCET
- Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells
- (2016) Johannes Leibacher et al. Stem Cell Research & Therapy
- Allogeneic Mesenchymal Precursor Cells (MPC) in Diabetic Nephropathy: A Randomized, Placebo-controlled, Dose Escalation Study
- (2016) David K. Packham et al. EBioMedicine
- Identification of IL-1β and LPS as optimal activators of monolayer and alginate-encapsulated mesenchymal stromal cell immunomodulation using design of experiments and statistical methods
- (2015) Andrea Gray et al. BIOTECHNOLOGY PROGRESS
- Allogeneic Mesenchymal Precursor Cells in Type 2 Diabetes: A Randomized, Placebo-Controlled, Dose-Escalation Safety and Tolerability Pilot Study
- (2015) Jay S. Skyler et al. DIABETES CARE
- Human Placenta-derived Cells (PDA-001) for the Treatment of Moderate-to-severe Crohnʼs Disease
- (2015) Gil Y. Melmed et al. INFLAMMATORY BOWEL DISEASES
- Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain
- (2015) Reint K. Jellema et al. Journal of Neuroinflammation
- Intrathecal transplantation of autologous adipose-derived mesenchymal stem cells for treating spinal cord injury: A human trial
- (2015) Junseok W. Hur et al. JOURNAL OF SPINAL CORD MEDICINE
- Challenges in animal modelling of mesenchymal stromal cell therapy for inflammatory bowel disease
- (2015) Raghavan Chinnadurai WORLD JOURNAL OF GASTROENTEROLOGY
- Mesenchymal stem cells as a therapeutic tool to treat sepsis
- (2015) Eleuterio Lombardo World Journal of Stem Cells
- Preserved β-Cell Function in Type 1 Diabetes by Mesenchymal Stromal Cells
- (2014) Per-Ola Carlsson et al. DIABETES
- Adult Human Mesenchymal Stem Cells Delivered via Intra-Articular Injection to the Knee Following Partial Medial Meniscectomy
- (2014) C Thomas Vangsness et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Soliciting Strategies for Developing Cell-Based Reference Materials to Advance Mesenchymal Stromal Cell Research and Clinical Translation
- (2014) Sowmya Viswanathan et al. STEM CELLS AND DEVELOPMENT
- Should Publications on Mesenchymal Stem/Progenitor Cells Include In-Process Data on the Preparation of the Cells?
- (2014) Roxanne L. Reger et al. Stem Cells Translational Medicine
- Mesenchymal stem cells: mechanisms of potential therapeutic benefit in ARDS and sepsis
- (2014) James Walter et al. Lancet Respiratory Medicine
- Enhancing the efficacy of mesenchymal stem cell therapy
- (2014) Michalis Mastri World Journal of Stem Cells
- Mesenchymal stem cells: a new trend for cell therapy
- (2013) Xin Wei et al. ACTA PHARMACOLOGICA SINICA
- Application of cell encapsulation for controlled delivery of biological therapeutics
- (2013) G. Orive et al. ADVANCED DRUG DELIVERY REVIEWS
- A Placebo-Controlled, Randomized Trial of Mesenchymal Stem Cells in COPD
- (2013) Daniel J. Weiss et al. CHEST
- A Phase 2 Study of Allogeneic Mesenchymal Stromal Cells for Luminal Crohn's Disease Refractory to Biologic Therapy
- (2013) Geoffrey M. Forbes et al. Clinical Gastroenterology and Hepatology
- Septic shock: desperately seeking treatment
- (2013) Olivier Huet et al. CLINICAL SCIENCE
- Adipose-derived mesenchymal stem cells for cartilage tissue engineering: State-of-The-Art inin vivostudies
- (2013) Francesca Veronesi et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Mesenchymal stem cells improve locomotor recovery in traumatic spinal cord injury: Systematic review with meta-analyses of rat models
- (2013) Roberto S. Oliveri et al. NEUROBIOLOGY OF DISEASE
- The global landscape of stem cell clinical trials
- (2013) Matthew D Li et al. Regenerative Medicine
- Cellular Encapsulation Enhances Cardiac Repair
- (2013) Rebecca D. Levit et al. Journal of the American Heart Association
- Safety and efficacy of mesenchymal stromal cell therapy in autoimmune disorders
- (2012) Maria Ester Bernardo et al. Annals of the New York Academy of Sciences
- Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjogren syndrome
- (2012) J. Xu et al. BLOOD
- Induction Therapy With Autologous Mesenchymal Stem Cells in Living-Related Kidney Transplants
- (2012) Jianming Tan et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Stem cells as promising therapeutic options for neurological disorders
- (2012) Jongman Yoo et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Alginate microencapsulation of human mesenchymal stem cells as a strategy to enhance paracrine-mediated vascular recovery after hindlimb ischaemia
- (2012) Natalia Landázuri et al. Journal of Tissue Engineering and Regenerative Medicine
- Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study
- (2012) Peter Connick et al. LANCET NEUROLOGY
- Encapsulated mesenchymal stromal cells for in vivo transplantation
- (2011) Jeffrey Barminko et al. BIOTECHNOLOGY AND BIOENGINEERING
- Cotransplantation of Mesenchymal Stem Cells Might Prevent Death from Graft-versus-Host Disease (GVHD) without Abrogating Graft-versus-Tumor Effects after HLA-Mismatched Allogeneic Transplantation following Nonmyeloablative Conditioning
- (2010) Frédéric Baron et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6
- (2009) Ryang Hwa Lee et al. Cell Stem Cell
- Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis
- (2009) E Gonzalez-Rey et al. GUT
- Heat Shock Protein-90 beta Is Expressed at the Surface of Multipotential Mesenchymal Precursor Cells: Generation of a Novel Monoclonal Antibody, STRO-4, With Specificity for Mesenchymal Precursor Cells From Human and Ovine Tissues
- (2009) Stan Gronthos et al. STEM CELLS AND DEVELOPMENT
- Evaluation of Methylcellulose and Dimethyl Sulfoxide as the Cryoprotectants in a Serum-Free Freezing Media for Cryopreservation of Adipose-Derived Adult Stem Cells
- (2009) Sreedhar Thirumala et al. STEM CELLS AND DEVELOPMENT
- Why are MSCs therapeutic? New data: new insight
- (2008) AI Caplan JOURNAL OF PATHOLOGY
- Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect
- (2008) Uwe M. Fischer et al. STEM CELLS AND DEVELOPMENT
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started