An autism-causing calcium channel variant functions with selective autophagy to alter axon targeting and behavior
出版年份 2019 全文链接
标题
An autism-causing calcium channel variant functions with selective autophagy to alter axon targeting and behavior
作者
关键词
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出版物
PLoS Genetics
Volume 15, Issue 12, Pages e1008488
出版商
Public Library of Science (PLoS)
发表日期
2019-12-06
DOI
10.1371/journal.pgen.1008488
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A critical neurodevelopmental role for L-type voltage-gated calcium channels in neurite extension and radial migration
- (2018) Satoshi Kamijo et al. JOURNAL OF NEUROSCIENCE
- An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
- (2018) Siwei Chen et al. NATURE GENETICS
- The Heritability of Autism Spectrum Disorder
- (2017) Sven Sandin et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood
- (2017) N Dedic et al. MOLECULAR PSYCHIATRY
- Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases
- (2017) Holly A F Stessman et al. NATURE GENETICS
- Hotspots of missense mutation identify neurodevelopmental disorder genes and functional domains
- (2017) Madeleine R Geisheker et al. NATURE NEUROSCIENCE
- Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder
- (2017) Ryan K C Yuen et al. NATURE NEUROSCIENCE
- BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon
- (2017) Ginny G. Farías et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Whole exome sequencing reveals inherited and de novo variants in autism spectrum disorder: a trio study from Saudi families
- (2017) Bashayer Al-Mubarak et al. Scientific Reports
- Transition between synaptic branch formation and synaptogenesis is regulated by the lin-4 microRNA
- (2016) Yan Xu et al. DEVELOPMENTAL BIOLOGY
- KIF1A/UNC-104 Transports ATG-9 to Regulate Neurodevelopment and Autophagy at Synapses
- (2016) Andrea K.H. Stavoe et al. DEVELOPMENTAL CELL
- Comprehensive molecular testing in patients with high functioning autism spectrum disorder
- (2016) Maria Isabel Alvarez-Mora et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
- (2016) Elise B Robinson et al. NATURE GENETICS
- Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disability
- (2016) Stefan H Lelieveld et al. NATURE NEUROSCIENCE
- De novo genic mutations among a Chinese autism spectrum disorder cohort
- (2016) Tianyun Wang et al. Nature Communications
- An autism-associated mutation in CaV1.3 channels has opposing effects on voltage- and Ca2+-dependent regulation
- (2016) Worawan B. Limpitikul et al. Scientific Reports
- Regulation of Gap Junction Dynamics by UNC-44/ankyrin and UNC-33/CRMP through VAB-8 in C. elegans Neurons
- (2016) Lingfeng Meng et al. PLoS Genetics
- Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain
- (2016) Joanna M Dragich et al. eLife
- Long QT syndrome with craniofacial, digital, and neurologic features: Is it useful to distinguish between timothy syndrome types 1 and 2?
- (2015) Vinson Diep et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- CACNA1A haploinsufficiency causes cognitive impairment, autism and epileptic encephalopathy with mild cerebellar symptoms
- (2015) Lena Damaj et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Erratum: Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons
- (2015) T Yoshimizu et al. MOLECULAR PSYCHIATRY
- The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators
- (2015) Rachel Kaletsky et al. NATURE
- Whole-genome sequencing of quartet families with autism spectrum disorder
- (2015) Ryan K C Yuen et al. NATURE MEDICINE
- Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms
- (2015) Alissa M. D’Gama et al. NEURON
- Schizophrenia Related Variants in CACNA1C also Confer Risk of Autism
- (2015) Jun Li et al. PLoS One
- Synergistic Interactions between Drosophila Orthologues of Genes Spanned by De Novo Human CNVs Support Multiple-Hit Models of Autism
- (2015) Stuart J. Grice et al. PLoS Genetics
- Synaptic, transcriptional and chromatin genes disrupted in autism
- (2014) Silvia De Rubeis et al. NATURE
- The contribution of de novo coding mutations to autism spectrum disorder
- (2014) Ivan Iossifov et al. NATURE
- Rare Mutations of CACNB2 Found in Autism Spectrum Disease-Affected Families Alter Calcium Channel Function
- (2014) Alexandra F. S. Breitenkamp et al. PLoS One
- Massively Parallel Sequencing of Patients with Intellectual Disability, Congenital Anomalies and/or Autism Spectrum Disorders with a Targeted Gene Panel
- (2014) Maggie Brett et al. PLoS One
- Differences in the right inferior longitudinal fasciculus but no general disruption of white matter tracts in children with autism spectrum disorder
- (2014) Kami Koldewyn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Caenorhabditis elegans microtubule minus-end binding homolog PTRN-1 stabilizes synapses and neurites
- (2014) Jana Dorfman Marcette et al. eLife
- Axonal deficits in young adults with High Functioning Autism and their impact on processing speed
- (2014) Mariana Lazar et al. NeuroImage-Clinical
- Detection of Clinically Relevant Genetic Variants in Autism Spectrum Disorder by Whole-Genome Sequencing
- (2013) Yong-hui Jiang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The scaffold protein EPG-7 links cargo–receptor complexes with the autophagic assembly machinery
- (2013) Long Lin et al. JOURNAL OF CELL BIOLOGY
- Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
- (2013) LANCET
- Autophagy Negatively Regulates Early Axon Growth in Cortical Neurons
- (2013) B.-K. Ban et al. MOLECULAR AND CELLULAR BIOLOGY
- Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons
- (2013) Jocelyn F Krey et al. NATURE NEUROSCIENCE
- Differences in White Matter Fiber Tract Development Present From 6 to 24 Months in Infants With Autism
- (2012) Jason J. Wolff et al. AMERICAN JOURNAL OF PSYCHIATRY
- Diffusion Tensor Imaging in Autism Spectrum Disorder: A Review
- (2012) Brittany G. Travers et al. Autism Research
- MIG-10 Functions with ABI-1 to Mediate the UNC-6 and SLT-1 Axon Guidance Signaling Pathways
- (2012) Yan Xu et al. PLoS Genetics
- Support for calcium channel gene defects in autism spectrum disorders
- (2012) Ake Tzu-Hui Lu et al. Molecular Autism
- Phenotypical Manifestations of Mutations in the Genes Encoding Subunits of the Cardiac Voltage–Dependent L-Type Calcium Channel
- (2011) Carlo Napolitano et al. CIRCULATION RESEARCH
- PPM-1, a PP2Cα/β phosphatase, Regulates Axon Termination and Synapse Formation inCaenorhabditis elegans
- (2011) Erik D. Tulgren et al. GENETICS
- Oligogenic heterozygosity in individuals with high-functioning autism spectrum disorders
- (2011) C. P. Schaaf et al. HUMAN MOLECULAR GENETICS
- The α1 Subunit EGL-19, the α2/δ Subunit UNC-36, and the β Subunit CCB-1 Underlie Voltage-dependent Calcium Currents inCaenorhabditis elegansStriated Muscle
- (2011) Viviane Lainé et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mouse model of Timothy syndrome recapitulates triad of autistic traits
- (2011) P. L. Bader et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
- (2010) Terje Høyvarde Clausen et al. Autophagy
- The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy
- (2010) Maria Filimonenko et al. MOLECULAR CELL
- mec-15 Encodes an F-Box Protein Required for Touch Receptor Neuron Mechanosensation, Synapse Formation and Development
- (2009) A. Bounoutas et al. GENETICS
- Autophagy promotes synapse development inDrosophila
- (2009) Wei Shen et al. JOURNAL OF CELL BIOLOGY
- High-density SNP association study of the 17q21 chromosomal region linked to autism identifies CACNA1G as a novel candidate gene
- (2009) S P Strom et al. MOLECULAR PSYCHIATRY
- Presynaptic CaV2 calcium channel traffic requires CALF-1 and the α2δ subunit UNC-36
- (2009) Yasunori Saheki et al. NATURE NEUROSCIENCE
- A Genetic Screen for Dihydropyridine (DHP)-Resistant Worms Reveals New Residues Required for DHP-Blockage of Mammalian Calcium Channels
- (2008) Trevor C. Y. Kwok et al. PLoS Genetics
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