Cadmium Induces Acute Liver Injury by Inhibiting Nrf2 and the Role of NF-κB, NLRP3, and MAPKs Signaling Pathway

Toxic Effect of Acute Cadmium and Lead Exposure in Rat Blood, Liver, and Kidney

(2019) Milena Andjelkovic et al.   International Journal of Environmental Research and Public Health

Effect of Prepubertal Exposure to CdCl2 on the Liver, Hematological, and Biochemical Parameters in Female Rats; an Experimental Study

(2019) Saman Saedi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Royal jelly attenuates cadmium-induced nephrotoxicity in male mice

(2019) Rafa S. Almeer et al.   Scientific Reports

Augmentation of cadmium-induced oxidative cytotoxicity by pioglitazone in renal tubular epithelial cells

(2019) Keiko Hosohata et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Canonical and non-canonical mechanisms of Nrf2 activation

(2018) Carlos Alfredo Silva-Islas et al.   PHARMACOLOGICAL RESEARCH

Review of polyphenol-rich products as potential protective and therapeutic factors against cadmium hepatotoxicity

(2018) Magdalena Mężyńska et al.   JOURNAL OF APPLIED TOXICOLOGY

Cadmium-induced hepatocellular injury: Modulatory effects of γ-glutamyl cysteine on the biomarkers of inflammation, DNA damage, and apoptotic cell death

(2018) Samir A. Salama et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Environmental exposure to cadmium—a risk for health of the general population in industrialized countries and preventive strategies

(2017) Magdalena Mezynska et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Nrf2/ARE pathway inhibits ROS-induced NLRP3 inflammasome activation in BV2 cells after cerebral ischemia reperfusion

(2017) Xiujian Xu et al.   INFLAMMATION RESEARCH

Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome

(2017) Zhengwang Cao et al.   JOURNAL OF PINEAL RESEARCH

Non-infective occupational risk factors for hepatocellular carcinoma: A review

(2016) Caterina Ledda et al.   Molecular Medicine Reports

Oxidative Signaling Response to Cadmium Exposure

(2016) Saïd Nemmiche   TOXICOLOGICAL SCIENCES

Cadmium induces NLRP3 inflammasome-dependent pyroptosis in vascular endothelial cells

(2016) Haiyan Chen et al.   TOXICOLOGY LETTERS

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome

(2015) Justyna Rzepecka et al.   JOURNAL OF AUTOIMMUNITY

In vitro studies on mangiferin protection against cadmium-induced human renal endothelial damage and cell death via the MAP kinase and NF-κB pathways

(2015) Peramaiyan Rajendran et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Salidroside Protects against Cadmium-Induced Hepatotoxicity in Rats via GJIC and MAPK Pathways

(2015) Hui Zou et al.   PLoS One

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation

(2013) M. E. Heid et al.   JOURNAL OF IMMUNOLOGY

Nrf2 activation prevents cadmium-induced acute liver injury

(2012) Kai C. Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondrial ROS fuel the inflammasome

(2011) Matthew T Sorbara et al.   CELL RESEARCH

Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway

(2011) Miao Yu et al.   CELLULAR SIGNALLING

Calcium Signaling Is Involved in Cadmium-Induced Neuronal Apoptosis via Induction of Reactive Oxygen Species and Activation of MAPK/mTOR Network

(2011) Baoshan Xu et al.   PLoS One

Cadmium exposure in the population: from health risks to strategies of prevention

(2010) Tim S. Nawrot et al.   BIOMETALS

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Role of oxidative stress and MAPK signaling in reference moist smokeless tobacco-induced HOK-16B cell death

(2010) Clint Mitchell et al.   TOXICOLOGY LETTERS

Cadmium-induced apoptotic death of human retinal pigment epithelial cells is mediated by MAPK pathway

(2009) Nilesh M. Kalariya et al.   EXPERIMENTAL EYE RESEARCH

Antiviral Activity of Nrf2 in a Murine Model of Respiratory Syncytial Virus Disease

(2008) Hye-Youn Cho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK

(2008) Guang-Hui Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Heterodimerization with small Maf proteins enhances nuclear retention of Nrf2 via masking the NESzip motif

(2008) Wenge Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

(2008) Long Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE