The Investigation of Hippocampus-Dependent Cognitive Decline Induced by Anesthesia/Surgery in Mice Through Integrated Behavioral Z-Scoring

Mouse models of neurodegeneration: Know your question, know your mouse

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Postoperative Delirium Is Associated with Long-term Decline in Activities of Daily Living

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Methane ameliorates post-operative cognitive dysfunction by inhibiting microglia NF-κB/MAPKs pathway and promoting IL-10 expression in aged mice

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Interleukin-6 is both necessary and sufficient to produce perioperative neurocognitive disorder in mice

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Upregulation of TREM2 Ameliorates Neuroinflammatory Responses and Improves Cognitive Deficits Triggered by Surgical Trauma in Appswe/PS1dE9 Mice

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Reclassification of Bronchodilator Reversibility in the U-BIOPRED Adult Asthma Cohort Using z  Scores

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An improved procedure for integrated behavioral z-scoring illustrated with modified Hole Board behavior of male inbred laboratory mice

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Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats

(2018) Fabricio M. Locatelli et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Varenicline reduces DNA damage, tau mislocalization and post surgical cognitive impairment in aged mice

(2018) Chunxia Huang et al.   NEUROPHARMACOLOGY

Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery—2018

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IL-17A contributes to perioperative neurocognitive disorders through blood-brain barrier disruption in aged mice

(2018) Pengfei Ni et al.   Journal of Neuroinflammation

Anesthesia and Surgery Impair Blood–Brain Barrier and Cognitive Function in Mice

(2017) Siming Yang et al.   Frontiers in Immunology

Cerebral mast cells contribute to postoperative cognitive dysfunction by promoting blood brain barrier disruption

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Consomic mouse strain selection based on effect size measurement, statistical significance testing and integrated behavioral z-scoring: focus on anxiety-related behavior and locomotion

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Prior stressor exposure delays the recovery of surgery-induced cognitive impairment and prolongs neuroinflammation in aged rats

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Berberine alleviates postoperative cognitive dysfunction by suppressing neuroinflammation in aged mice

(2016) Zhijie Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activated brain mast cells contribute to postoperative cognitive dysfunction by evoking microglia activation and neuronal apoptosis

(2016) Xiang Zhang et al.   Journal of Neuroinflammation

Battery of behavioral tests in mice to study postoperative delirium

(2016) Mian Peng et al.   Scientific Reports

Folates and aging: Role in mild cognitive impairment, dementia and depression

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Impact of Preoperative Environmental Enrichment on Prevention of Development of Cognitive Impairment following Abdominal Surgery in a Rat Model

(2015) Takashi Kawano et al.   ANESTHESIOLOGY

Amantadine Alleviates Postoperative Cognitive Dysfunction Possibly by Increasing Glial Cell Line-derived Neurotrophic Factor in Rats

(2014) Junfeng Zhang et al.   ANESTHESIOLOGY

Postoperative cognitive dysfunction: Involvement of neuroinflammation and neuronal functioning

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Incidence of postoperative cognitive dysfunction after general or spinal anaesthesia for extracorporeal shock wave lithotripsy

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Surgery Results in Exaggerated and Persistent Cognitive Decline in a Rat Model of the Metabolic Syndrome

(2013) Xiaomei Feng et al.   ANESTHESIOLOGY

Depletion of Bone Marrow–derived Macrophages Perturbs the Innate Immune Response to Surgery and Reduces Postoperative Memory Dysfunction

(2013) Vincent Degos et al.   ANESTHESIOLOGY

Surgery-induced behavioral changes in aged rats

(2013) Iris B. Hovens et al.   EXPERIMENTAL GERONTOLOGY

Object recognition test in mice

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An old test for new neurons: refining the Morris water maze to study the functional relevance of adult hippocampal neurogenesis

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Thinking through postoperative cognitive dysfunction: How to bridge the gap between clinical and pre-clinical perspectives

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Resolving postoperative neuroinflammation and cognitive decline

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When Is the Hippocampus Involved in Recognition Memory?

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Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: Relevance to emotionality and sex

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Role of interleukin-1β in postoperative cognitive dysfunction

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Tumor necrosis factor-  triggers a cytokine cascade yielding postoperative cognitive decline

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Long-term Consequences of Postoperative Cognitive Dysfunction

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