A M35 family metalloprotease is required for fungal virulence against insects by inactivating host prophenoloxidases and beyond

Unveiling the function and regulation control of the DUF3129 family proteins in fungal infection of hosts

(2019) Wei Huang et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Horizontal gene transfer allowed the emergence of broad host range entomopathogens

(2019) Qiangqiang Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

More Than Black or White: Melanization and Toll Share Regulatory Serine Proteases in Drosophila

(2019) Jan Paul Dudzic et al.   Cell Reports

MrSt12 implicated in the regulation of transcription factor AFTF1 by Fus3-MAPK during cuticle penetration by the entomopathogenic fungus Metarhizium robertsii

(2019) Yamin Meng et al.   FUNGAL GENETICS AND BIOLOGY

A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection

(2019) Chunlai Cui et al.   Nature Communications

Insecticidal activity of the metalloprotease AprA occurs through suppression of host cellular and humoral immunity

(2018) Seung Ah Lee et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Evolutionary ecology of parasitic fungi and their host insects

(2018) Andreas Vilcinskas   Fungal Ecology

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

(2018) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Circulating Protease Persephone Is an Immune Sensor for Microbial Proteolytic Activities Upstream of the Drosophila Toll Pathway

(2018) Najwa Issa et al.   MOLECULAR CELL

Dual function of a secreted fungalysin metalloprotease in Ustilago maydis

(2018) Bilal Ökmen et al.   NEW PHYTOLOGIST

The entomopathogenic fungus Metarhizium robertsii communicates with the insect host Galleria mellonella during infection

(2018) Krishnendu Mukherjee et al.   Virulence

Duplication of a Pks gene cluster and subsequent functional diversification facilitate environmental adaptation in Metarhizium species

(2018) Guohong Zeng et al.   PLoS Genetics

Differential Functions of Two Metalloproteases, Mrmep1 and Mrmep2, in Growth, Sporulation, Cell Wall Integrity, and Virulence in the Filamentous Fungus Metarhizium robertsii

(2018) Rong Zhou et al.   Frontiers in Microbiology

Manipulation of the silkworm immune system by a metalloprotease from the pathogenic bacterium Pseudomonas aeruginosa

(2018) Li Ma et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects

(2018) Xiaolong Cao et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cyclosporine Biosynthesis in Tolypocladium inflatum Benefits Fungal Adaptation to the Environment

(2018) Xiuqing Yang et al.   mBio

A Metalloprotease Homolog Venom Protein From a Parasitoid Wasp Suppresses the Toll Pathway in Host Hemocytes

(2018) Zhe Lin et al.   Frontiers in Immunology

Correlation of cell surface proteins of distinct Beauveria bassiana cell types and adaption to varied environment and interaction with the host insect

(2017) Zhi Yang et al.   FUNGAL GENETICS AND BIOLOGY

The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database

(2017) Neil D Rawlings et al.   NUCLEIC ACIDS RESEARCH

Divergent LysM effectors contribute to the virulence of Beauveria bassiana by evasion of insect immune defenses

(2017) Kai Cen et al.   PLoS Pathogens

Prophenoloxidase-Mediated Ex Vivo Immunity to Delay Fungal Infection after Insect Ecdysis

(2017) Jie Zhang et al.   Frontiers in Immunology

Divergent and Convergent Evolution of Fungal Pathogenicity

(2016) Yanfang Shang et al.   Genome Biology and Evolution

Drosophila innate immunity: regional and functional specialization of prophenoloxidases

(2015) Jan P. Dudzic et al.   BMC BIOLOGY

Fungal biosynthesis of the bibenzoquinone oosporein to evade insect immunity

(2015) Peng Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant Drosophila prophenoloxidase 1 is sequentially cleaved by α-chymotrypsin during in vitro activation

(2014) Anrui Lu et al.   BIOCHIMIE

Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation

(2014) Xiao Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host-to-Pathogen Gene Transfer Facilitated Infection of Insects by a Pathogenic Fungus

(2014) Hong Zhao et al.   PLoS Pathogens

Prophenoloxidase Activation Is Required for Survival to Microbial Infections in Drosophila

(2014) Olivier Binggeli et al.   PLoS Pathogens

Advances in fundamental and applied studies in China of fungal biocontrol agents for use against arthropod pests

(2013) Chengshu Wang et al.   BIOLOGICAL CONTROL

The Apoptogenic Toxin AIP56 Is a Metalloprotease A-B Toxin that Cleaves NF-κb P65

(2013) Daniela S. Silva et al.   PLoS Pathogens

Fungal zinc metabolism and its connections to virulence

(2013) Charley C. Staats et al.   Frontiers in Cellular and Infection Microbiology

Action on the Surface: Entomopathogenic Fungi versus the Insect Cuticle

(2013) Almudena Ortiz-Urquiza et al.   Insects

Unveiling the biosynthetic puzzle of destruxins in Metarhizium species

(2012) B. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Properties of Drosophila melanogaster prophenoloxidases expressed in Escherichia coli

(2011) Xuquan Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Fungal Proteases and Their Pathophysiological Effects

(2011) Iwona Yike   MYCOPATHOLOGIA

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Monalysin, a Novel ß-Pore-Forming Toxin from the Drosophila Pathogen Pseudomonas entomophila, Contributes to Host Intestinal Damage and Lethality

(2011) Onya Opota et al.   PLoS Pathogens

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

Metalloprotease type III effectors that specifically cleave JNK and NF-κB

(2010) Kobi Baruch et al.   EMBO JOURNAL

The Drosophila PRR GNBP3 assembles effector complexes involved in antifungal defenses independently of its Toll-pathway activation function

(2010) Alexey A. Matskevich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Insecticidal evaluation of Beauveria bassiana engineered to express a scorpion neurotoxin and a cuticle degrading protease

(2008) Dingding Lu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The AsaP1 Peptidase of Aeromonas salmonicida subsp. achromogenes Is a Highly Conserved Deuterolysin Metalloprotease (Family M35) and a Major Virulence Factor

(2008) H. Arnadottir et al.   JOURNAL OF BACTERIOLOGY

Toll-like receptors — taking an evolutionary approach

(2008) François Leulier et al.   NATURE REVIEWS GENETICS

The proPO-system: pros and cons for its role in invertebrate immunity

(2008) Lage Cerenius et al.   TRENDS IN IMMUNOLOGY