Delivering Crocetin across the Blood-Brain Barrier by Using γ-Cyclodextrin to Treat Alzheimer’s Disease
出版年份 2020 全文链接
标题
Delivering Crocetin across the Blood-Brain Barrier by Using γ-Cyclodextrin to Treat Alzheimer’s Disease
作者
关键词
-
出版物
Scientific Reports
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-02-27
DOI
10.1038/s41598-020-60293-y
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Review of Current Strategies for Delivering Alzheimer’s Disease Drugs across the Blood-Brain Barrier
- (2019) Ka Wong et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Antioxidant Properties of Crocus Sativus L. and its Constituents and Relevance to Neurodegenerative Diseases; Focus on Alzheimer’s And Parkinson’s disease
- (2018) Kyriaki Hatziagapiou et al. Current Neuropharmacology
- The amyloid hypothesis on trial
- (2018) Simon Makin NATURE
- Crocetin attenuates inflammation and amyloid-β accumulation in APPsw transgenic mice
- (2018) Jin Zhang et al. Immunity & Ageing
- Pharmacokinetic Properties of Saffron and its Active Components
- (2017) Azar Hosseini et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Trans -crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients
- (2017) Roberto Tiribuzi et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Anti-amyloid aggregation activity of novel carotenoids: implications for Alzheimer’s drug discovery
- (2017) Johant Lakey-Beitia et al. Clinical Interventions in Aging
- Cyclodextrins as Emerging Therapeutic Tools in the Treatment of Cholesterol-Associated Vascular and Neurodegenerative Diseases
- (2016) Caroline Coisne et al. MOLECULES
- The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review
- (2016) Shanmugam Manoharan et al. Oxidative Medicine and Cellular Longevity
- Intestinal formation of trans-crocetin from saffron extract (Crocus sativus L.) and in vitro permeation through intestinal and blood brain barrier
- (2015) M. Lautenschläger et al. PHYTOMEDICINE
- A review of the chemistry and uses of crocins and crocetin, the carotenoid natural dyes in saffron, with particular emphasis on applications as colorants including their use as biological stains
- (2014) SZ Bathaie et al. BIOTECHNIC & HISTOCHEMISTRY
- Review: A History of Cyclodextrins
- (2014) Grégorio Crini CHEMICAL REVIEWS
- Neuropathological Alterations in Alzheimer Disease
- (2013) A. Serrano-Pozo et al. Cold Spring Harbor Perspectives in Medicine
- β-Cyclodextrin-poly(β-Amino Ester) Nanoparticles for Sustained Drug Delivery across the Blood–Brain Barrier
- (2012) Eun Seok Gil et al. BIOMACROMOLECULES
- Investigation of the neuroprotective action of saffron (Crocus sativus L.) in aluminum-exposed adult mice through behavioral and neurobiochemical assessment
- (2012) Zacharoula I. Linardaki et al. FOOD AND CHEMICAL TOXICOLOGY
- Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease
- (2012) Jiaqi Yao et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Memory enhancing effects of saffron in aged mice are correlated with antioxidant protection
- (2011) Magdalini A. Papandreou et al. BEHAVIOURAL BRAIN RESEARCH
- Crocetin inhibits beta-amyloid fibrillization and stabilizes beta-amyloid oligomers
- (2011) Joon Ho Ahn et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Crocetin reduces the oxidative stress induced reactive oxygen species in the stroke-prone spontaneously hypertensive rats (SHRSPs) brain
- (2011) Fumihiko Yoshino et al. JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION
- A new validated SPE-HPLC method for monitoring crocetin in human plasma—Application after saffron tea consumption
- (2011) Dimitra G. Chryssanthi et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- A Peptide That Binds Specifically to the β-Amyloid of Alzheimer's Disease: Selection and Assessment of Anti-β-Amyloid Neurotoxic Effects
- (2011) Fang Wang et al. PLoS One
- PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel
- (2010) Yong Zhang et al. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
- Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells
- (2010) Kyong Nyon Nam et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The pharmacokinetic profile of crocetin in healthy adult human volunteers after a single oral administration
- (2010) N. Umigai et al. PHYTOMEDICINE
- Cyclodextrin Inclusion Complex Formation and Solid-State Characterization of the Natural Antioxidants α-Tocopherol and Quercetin
- (2009) John L. Koontz et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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