Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates

Early short-term PXT3003 combinational therapy delays disease onset in a transgenic rat model of Charcot-Marie-Tooth disease 1A (CMT1A)

(2019) Thomas Prukop et al.   PLoS One

Glucose Metabolism as a Pre-clinical Biomarker for the Golden Retriever Model of Duchenne Muscular Dystrophy

(2018) Sarah Morar Schneider et al.   MOLECULAR IMAGING AND BIOLOGY

Muscle Atrophy Due to Nerve Damage Is Accompanied by Elevated Myofibrillar Protein Synthesis Rates

(2018) Henning T. Langer et al.   Frontiers in Physiology

Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle

(2017) Aurelia Defour et al.   HUMAN MOLECULAR GENETICS

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

(2017) Thomas J. Park et al.   SCIENCE

Muscle LIM Protein: Master regulator of cardiac and skeletal muscle functions

(2015) Elizabeth Vafiadaki et al.   GENE

Acute resistance exercise activates rapamycin-sensitive and -insensitive mechanisms that control translational activity and capacity in skeletal muscle

(2015) Daniel W. D. West et al.   JOURNAL OF PHYSIOLOGY-LONDON

An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A

(2014) Shahram Attarian et al.   Orphanet Journal of Rare Diseases

Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy

(2014) Ilya Chumakov et al.   Orphanet Journal of Rare Diseases

Stain-Free total protein staining is a superior loading control to β-actin for Western blots

(2013) Jennifer E. Gilda et al.   ANALYTICAL BIOCHEMISTRY

Critical Illness Myopathy and GLUT4

(2012) Steffen Weber-Carstens et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Aldose Reductase, Oxidative Stress, and Diabetic Mellitus

(2012) Wai Ho Tang et al.   Frontiers in Pharmacology

Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms

(2011) Julien Ochala et al.   JOURNAL OF PHYSIOLOGY-LONDON

The use of total protein stains as loading controls: An alternative to high-abundance single-protein controls in semi-quantitative immunoblotting

(2008) Georgina M. Aldridge et al.   JOURNAL OF NEUROSCIENCE METHODS