Toxicology of paraquat and pharmacology of the protective effect of 5-hydroxy-1-methylhydantoin on lung injury caused by paraquat based on metabolomics

Biomarker Discovery for Cytochrome P450 1A2 Activity Assessment in Rats, Based on Metabolomics

(2019) Xiao Pu et al.   Metabolites

Protective mechanism of 1-methylhydantoin against lung injury induced by paraquat poisoning

(2019) Bo Liu et al.   PLoS One

Protective role of thymoquinone against paraquat-induced hepatotoxicity in mice

(2018) Hamed Zeinvand-Lorestani et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by irinotecan

(2018) Yiqiao Gao et al.   Acta Pharmaceutica Sinica B

Hypotaurine Is a Substrate of GABA Transporter Family Members GAT2/Slc6a13 and TAUT/Slc6a6

(2018) Tomohiro Nishimura et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Exploring the potential benefit of natural product extracts in paraquat toxicity

(2018) Zacharias E. Suntres   FITOTERAPIA

Beneficial effects of ascorbic acid to treat lung fibrosis induced by paraquat

(2018) Marcia Rodrigues da Silva et al.   PLoS One

Protective Effect of Anthocyanin on Paraquat-Induced Apoptosis and Epithelial-Mesenchymal Transition in Alveolar Type II Cells

(2018) Zhihua Wang et al.   MEDICAL SCIENCE MONITOR

Reaction of hypotaurine or taurine with superoxide produces the organic peroxysulfonic acid peroxytaurine

(2017) Roxanna Q. Grove et al.   FREE RADICAL BIOLOGY AND MEDICINE

Renal Medulla is More Sensitive to Cisplatin than Cortex Revealed by Untargeted Mass Spectrometry-Based Metabolomics in Rats

(2017) Pei Zhang et al.   Scientific Reports

Glucose Metabolism and AMPK Signaling Regulate Dopaminergic Cell Death Induced by Gene (α-Synuclein)-Environment (Paraquat) Interactions

(2016) Annadurai Anandhan et al.   MOLECULAR NEUROBIOLOGY

Unfractionated bone marrow cells attenuate paraquat-induced glomerular injury and acute renal failure by modulating the inflammatory response

(2016) Sing-Yi Gu et al.   Scientific Reports

Metabolic Changes in Paraquat Poisoned Patients and Support Vector Machine Model of Discrimination

(2015) Xianqin Wang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Creatinine metabolite, HMH (5-hydroxy-1-methylhydantoin; NZ-419), modulates bradykinin-induced changes in vascular smooth muscle cells

(2014) Kazuharu Ienaga et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Proline Modulates the Trypanosoma cruzi Resistance to Reactive Oxygen Species and Drugs through a Novel D, L-Proline Transporter

(2014) Melisa Sayé et al.   PLoS One

Mitochondrial Energy Metabolism and Redox Signaling in Brain Aging and Neurodegeneration

(2012) Fei Yin et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of Mammalian Target of Rapamycin Augments Lipopolysaccharide-Induced Lung Injury and Apoptosis

(2012) J. A. Fielhaber et al.   JOURNAL OF IMMUNOLOGY

Serum accumulation of a creatinine oxidative metabolite (NZ-419: 5-hydroxy-1- methylhydatoin) as an intrinsic antioxidant in diabetic patients with or without chronic kidney disease

(2011) G. Hasegawa et al.   CLINICAL NEPHROLOGY

Treatment with NZ-419 (5-Hydroxy-1-methylimidazoline-2,4-dione), a Novel Intrinsic Antioxidant, against the Progression of Chronic Kidney Disease at Stages 3 and 4 in Rats

(2010) Kazuharu Ienaga et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

First Indications Demonstrating the Preventive Effects of NZ-419, a Novel Intrinsic Antioxidant, on the Initiation and/or Progression of Chronic Renal Failure in Rats

(2009) Kazuharu Ienaga et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Paraquat Poisonings: Mechanisms of Lung Toxicity, Clinical Features, and Treatment

(2007) R. J. Dinis-Oliveira et al.   CRITICAL REVIEWS IN TOXICOLOGY

Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress

(2007) Navasona Krishnan et al.   FREE RADICAL BIOLOGY AND MEDICINE