Article
Entomology
Chaerin Kim, Jin-Myung Kim, Heeyun Choi, Yong-Soo Choi, Byung-Rae Jin, Kwang-Sik Lee, Kihyuck Choi
Summary: The global decline in wild bee population, especially the sudden disappearance of millions of managed bees in Korea, has raised concerns. This study found significant differences in the gut bacterial community between resistant and susceptible bees, suggesting that this difference may contribute to disease resistance.
JOURNAL OF APPLIED ENTOMOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Rajtilak Majumdar, Shyam L. Kandel, Jeffrey W. Cary, Kanniah Rajasekaran
Summary: This study analyzed the endophytic bacterial community in maize seeds resistant to aflatoxin contamination and identified potential bacterial markers associated with resistance. Functional profiling revealed differences in bacterial products between resistant and susceptible lines, indicating possible roles in resistance mechanisms. Future characterization of these bacteria may lead to the development of effective biocontrol agents for aflatoxin resistance in maize.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Cristina Zamora-Ballesteros, Gloria Pinto, Joana Amaral, Luis Valledor, Artur Alves, Julio J. Diez, Jorge Martin-Garcia
Summary: This study identified differences in molecular responses and physiological traits between the highly susceptible Pinus radiata and the highly resistant Pinus pinea to Fusarium circinatum at an early infection stage. While no significant changes were found in physiological analysis upon pathogen infection, transcriptional reprogramming was observed mainly in the resistant species.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Microbiology
Geromy G. Moore, Subbaiah Chalivendra, Brian M. Mack, Matthew K. Gilbert, Jeffrey W. Cary, Kanniah Rajasekaran
Summary: The introduction of non-aflatoxigenic biocontrol strains to maize plants significantly impacts the microbial communities, especially the bacterial communities. Beneficial microbes like Sarocladium that respond well to the biocontrol strains are expected to enhance biocontrol efficacy, while eliminating/antagonizing harmful microbes.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Laura Sheehy, Kerry MacDonald-Howard, Chris D. Williams, Gareth D. Weedall, Hayley Jones, Robbie Rae
Summary: Animals' gut microbiomes play a crucial role in various biological processes such as immunity and protection against pathogens. However, little is known about how the microbiome changes during parasite infection and in hosts with different susceptibility levels. In this study, we exposed two slug species with varying susceptibility to a parasitic nematode and examined their gut microbiota after infection. The results showed that infection caused dysbiosis in the microbiome of susceptible slugs, while the microbiome of resistant slugs remained unchanged. This suggests that nematode infection can alter the microbiome structure in susceptible hosts.
Article
Biochemistry & Molecular Biology
Tanya Brown, Dylan Sonett, Jesse R. Zaneveld, Jacqueline L. Padilla-Gamino
Summary: Coral diseases are increasing in frequency and intensity globally, and the etiology of many of these diseases remains poorly understood. Chronic Montipora white syndrome (cMWS) affects a major reef-building coral species in Hawai'i, and this study shows that the immunological and microbiological responses to cMWS are highly localized. Apparently healthy portions of corals with cMWS differ in immune activity and microbial taxa abundance compared to diseased parts, suggesting a localized effect on the coral microbiology and immunology, which may contribute to the slow progression of the disease.
Article
Multidisciplinary Sciences
J. Grace Klinges, Shalvi H. Patel, William C. Duke, Erinn M. Muller, Rebecca L. Vega Thurber
Summary: Chronic high levels of inorganic nutrients in Florida's coral reefs are associated with increased coral bleaching and disease severity. This study examined the impact of nutrient pollution on microbial community structure in a disease-resistant coral genotype. Results showed that prolonged nutrient enrichment led to shifts in microbiome diversity and composition, and reduced coral growth rates. Understanding how disease-resistant genotypes respond to environmental stressors is crucial for coral population management and restoration.
SCIENTIFIC REPORTS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jeffrey L. Ebersole, Sreenatha Kirakodu, Octovio Gonzalez
Summary: This study investigated the changes in the microbiome during the progression of periodontitis in rhesus monkeys. The results suggest that differences in disease expression related to periodontitis susceptibility may be explained by microbiome features.
MOLECULAR ORAL MICROBIOLOGY
(2023)
Article
Immunology
Ekaterina V. Grizanova, Tatiana I. Krytsyna, Galina V. Kalmykova, Elina Sokolova, Tatyana Alikina, Marsel Kabilov, Christopher J. Coates, Ivan M. Dubovskiy
Summary: This study investigated the progress of infection by Bacillus thuringiensis subsp. galleriae in wax moth larvae and shed light on the arms race between the bacteria's virulence and the insect's defenses. The results showed that resistant insects were able to quickly eliminate bacteria from their midgut, while susceptible insects did not. Additionally, resistant insects rapidly modulated their gene expression to initiate sporulation when exposed to the bacteria. It was also found that resistant insects had elevated levels of the antimicrobial peptide gloverin in their midgut, which serves as an evolutionary strategy to combat B. thuringiensis infection.
MICROBIAL PATHOGENESIS
(2023)
Article
Microbiology
Jun Li, Chenhui Zhang, Xinjing Qu, Ziqiong Luo, Sheng Lu, Yakov Kuzyakov, Hattan A. Alharbi, Jun Yuan, Genhua Niu
Summary: The rhizosphere microbiome of disease-resistant Camellia yuhsienensis is characterized by higher richness and diversity of microbial communities, more symbiotic fungi, and fewer pathogens compared to the rhizosphere of high-yield but disease-susceptible Camellia oleifera.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Parasitology
Davi Alvarenga Lima, Leilane Oliveira Goncalves, Joao Luis Reis-Cunha, Paul Anderson Souza Guimaraes, Jeronimo Conceicao Ruiz, Daniel Barbosa Liarte, Silvane Maria Fonseca Murta
Summary: This study performed comparative transcriptomic analysis of wildtype and benznidazole-resistant T. cruzi populations, revealing metabolic pathways related to clinical drug resistance and identifying promising molecular targets for the development of new drugs for Chagas disease.
PARASITES & VECTORS
(2023)
Article
Microbiology
Abigail S. Clark, Sara D. Williams, Kerry Maxwell, Stephanie M. Rosales, Lindsay K. Huebner, Jan H. Landsberg, John H. Hunt, Erinn M. Muller
Summary: The study revealed that coral colonies affected by SCTLD in five susceptible species exhibited specific microbial signatures, with the order Rhodobacterales and Clostridiales potentially playing key roles in the disease's progression. This suggests that stress-induced dysbiosis of coral microbiomes may contribute to the increase in opportunistic pathogens associated with SCTLD.
Article
Fisheries
Jiajie Zhu, Kai Yu, Qiuwei Ao, Yun Tan, Qiang Fu, Hesheng Jiang
Summary: Nile tilapia is a globally important fish for aquaculture, but Streptococcus agalactiae is a major disease threat in China. A study investigated the immune response of genetically improved farmed tilapia (GIFT) to S. agalactiae infection and found that disease-resistant tilapia had an upregulated immune response, cytoskeleton, and energy metabolism compared to susceptible strains. The findings contribute to understanding disease resistance mechanisms in GIFT tilapia and provide insights for breeding disease-resistant strains.
AQUACULTURE INTERNATIONAL
(2021)
Article
Fisheries
Debabrata Mondal, Usri Chakrabarty, Sourav Dutta, Ajoy Mallik, Nripendranath Mandal
Summary: This study identified and characterized novel miRNAs in virus-free disease-resistant and disease-susceptible Penaeus monodon, revealing a large number of known and new miRNAs in both samples. The differential expression study showed up-regulated and down-regulated miRNAs in disease-resistant and disease-susceptible P. monodon, suggesting a potential and specific role of P. monodon miRNAs in signal transduction, cell-to-cell signaling, innate immune response, and defense response to different pathogens.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Rajtilak Majumdar, Carl A. Strausbaugh, Eric D. Vincill, Imad Eujayl, Paul J. Galewski
Summary: Through sequencing and analysis of leaf bacteriome changes in different sugar beet genotypes in response to Beet curly top virus, this study identified potential bacteria with antiviral properties, providing insights for their use as biocontrol agents or biomarkers against the virus in the future.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)