Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer
出版年份 2020 全文链接
标题
Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer
作者
关键词
-
出版物
Scientific Reports
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-02-26
DOI
10.1038/s41598-020-60409-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles
- (2019) Aldenor G. Santos et al. Scientific Reports
- Antitumor Activity and Safety of Pembrolizumab in Patients with Advanced Recurrent Ovarian Cancer: Results from the Phase 2 KEYNOTE-100 Study
- (2019) U A Matulonis et al. ANNALS OF ONCOLOGY
- DNMT Inhibitors Increase Methylation in the Cancer Genome
- (2019) Anil K. Giri et al. Frontiers in Pharmacology
- Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist
- (2019) Kevin W Ng et al. eLife
- Synthetic lethal therapies for cancer: what’s next after PARP inhibitors?
- (2018) Alan Ashworth et al. Nature Reviews Clinical Oncology
- Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance
- (2018) Wei Zhou et al. ONCOGENE
- Repurposing Pan-HDAC Inhibitors for ARID1A -Mutated Ovarian Cancer
- (2018) Takeshi Fukumoto et al. Cell Reports
- Recent Advances in Targeting CD8 T-Cell Immunity for More Effective Cancer Immunotherapy
- (2018) Aurélie Durgeau et al. Frontiers in Immunology
- Effector CD8 T cells dedifferentiate into long-lived memory cells
- (2017) Ben Youngblood et al. NATURE
- ARID1A-mutated ovarian cancers depend on HDAC6 activity
- (2017) Benjamin G. Bitler et al. NATURE CELL BIOLOGY
- Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells
- (2017) Cornelia Siebenkäs et al. PLoS One
- Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden
- (2017) Meredith L. Stone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Combining Epigenetic and Immunotherapy to Combat Cancer
- (2016) Katherine B. Chiappinelli et al. CANCER RESEARCH
- CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma
- (2016) J. Walton et al. CANCER RESEARCH
- Essential role of HDAC6 in the regulation of PD-L1 in melanoma
- (2016) M. Lienlaf et al. Molecular Oncology
- De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+T-cell fate decisions following activation
- (2016) Brian H. Ladle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic Determinants of Cancer
- (2016) Stephen B. Baylin et al. Cold Spring Harbor Perspectives in Biology
- Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
- (2015) Suzanne L. Topalian et al. CANCER CELL
- DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
- (2015) David Roulois et al. CELL
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2015) Katherine B. Chiappinelli et al. CELL
- Genetic Engineering of T Cells to Target HERV-K, an Ancient Retrovirus on Melanoma
- (2015) J. Krishnamurthy et al. CLINICAL CANCER RESEARCH
- Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation
- (2015) K.V. Woan et al. Molecular Oncology
- Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells
- (2015) Edward J. Grow et al. NATURE
- Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets.
- (2015) Pamela L. Strissel et al. Oncotarget
- Alterations of immune response of non-small cell lung cancer with Azacytidine
- (2015) John Wrangle et al. Oncotarget
- Endogenous Retroviruses and the Development of Cancer
- (2014) G. Kassiotis JOURNAL OF IMMUNOLOGY
- A Novel Role for Histone Deacetylase 6 in the Regulation of the Tolerogenic STAT3/IL-10 Pathway in APCs
- (2014) Fengdong Cheng et al. JOURNAL OF IMMUNOLOGY
- Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells
- (2014) Fengdong Cheng et al. MOLECULAR IMMUNOLOGY
- Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
- (2014) Katrina J. Falkenberg et al. NATURE REVIEWS DRUG DISCOVERY
- Epigenetic Resensitization to Platinum in Ovarian Cancer
- (2012) D. Matei et al. CANCER RESEARCH
- De NovoDNA Methylation Is Required to Restrict T Helper Lineage Plasticity
- (2012) Rajan M. Thomas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
- (2011) R. D. Schreiber et al. SCIENCE
- Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation
- (2010) Sven Stengel et al. GENES CHROMOSOMES & CANCER
- The Role of HDAC6 in Cancer
- (2010) Grace I. Aldana-Masangkay et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Custom human endogenous retroviruses dedicated microarray identifies self-induced HERV-W family elements reactivated in testicular cancer upon methylation control
- (2010) Juliette Gimenez et al. NUCLEIC ACIDS RESEARCH
- Syncytin immunoreactivity in colorectal cancer: Potential prognostic impact
- (2009) Julie Mou Larsen et al. CANCER LETTERS
- Identification of DNA Methyltransferase 3a as a T Cell Receptor-Induced Regulator of Th1 and Th2 Differentiation
- (2009) C. J. Gamper et al. JOURNAL OF IMMUNOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started