Article
Biochemistry & Molecular Biology
Josefa Alarcon Apablaza, Fernando Jose Dias, Karina Godoy Sanchez, Pablo Navarro, Camila Venegas, Ramon Fuentes
Summary: This study investigated the osseointegration of a dental implant by analyzing its surface morphology and chemical composition microscopically. The implant surface was mainly composed of titanium and carbon, while the surrounding bone tissue contained phosphorus, calcium, oxygen, and carbon, showing excellent biocompatibility.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Jeong-Kui Ku, In-Woong Um, Mi-Kyoung Jun, Il-hyung Kim
Summary: This study reported a successful outcome in guided bone regeneration and dental implantation using a dentin-derived-barrier membrane made from autogenous demineralized dentin matrix. The novel human-derived collagen membrane overcame mechanical instability issues and demonstrated good osteo-inductive properties and mechanical stability in comparison with traditional methods. Further research should focus on evaluating bone forming capacity in large numbers of patients.
Review
Dentistry, Oral Surgery & Medicine
Shan-Huey Yu, Muhammad H. A. Saleh, Hom-Lay Wang
Summary: Lateral ridge augmentation is a common surgical procedure done either before or simultaneously with implant placement. The decision to do it simultaneously or in stages depends on multiple factors. This paper proposes a decision-making process to guide the selection of the best treatment based on available evidence and the author's clinical experience.
PERIODONTOLOGY 2000
(2023)
Review
Polymer Science
Manuel Toledano-Osorio, Cristina Vallecillo, Marta Vallecillo-Rivas, Francisco-Javier Manzano-Moreno, Raquel Osorio
Summary: Polymeric membranes are commonly utilized in bone regeneration for oral and periodontal surgeries by providing mechanical support and enhancing cell proliferation. Local antibiotic therapy using polymeric membranes has shown promising antibacterial effects, although further research and clinical studies are needed for validation.
Review
Biology
Javier Sanchez-Sanchez, Finn Niclas Pickert, Luis Sanchez-Labrador, Francisco G. F. Tresguerres, Jose Maria Martinez-Gonzalez, Cristina Meniz-Garcia
Summary: With the emergence of novel regeneration techniques in implant dentistry, professionals may question which technique to use in practice. This systematic review compared the Khoury and Urban techniques for horizontal alveolar ridge augmentation and found both to be effective in achieving bone gain. However, due to limited literature and lack of comparative studies, further research is needed to better evaluate the results.
Article
Dentistry, Oral Surgery & Medicine
Jin-Young Park, Young Woo Song, Kyung-A Ko, Franz-Josef Strauss, Daniel Stefan Thoma, Jung-Seok Lee
Summary: This study found that membrane fixation had no significant effect on ridge volume stability regardless of the type of membrane. However, in some cases, membrane fixation may increase ridge width at the coronal portion.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Goran Benic, Stefan P. Bienz, Young Woo Song, Jae-Kook Cha, Christoph H. F. Hammerle, Ui-Won Jung, Ronald E. Jung
Summary: This study aimed to compare the efficacy of soft-type block bone substitute and particulate bone substitute in guided bone regeneration of peri-implant defects. The results showed that there was no significant difference in the dimension of the augmented hard tissue between the two materials after 6 months of healing.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Jae-Hong Lee, Eun-Hee Jung, Seong-Nyum Jeong
Summary: The purpose of this study was to evaluate the stability and maintenance of peri-implant soft and hard tissues in the maxillary anterior region after guided bone regeneration (GBR) using L-shaped collagenated bone substitute and subepithelial connective tissue graft (CTG). The results showed an increase in soft tissue thickness and a decrease in hard tissue thickness after one year, with no significant difference in total tissue thickness. Volumetric changes in the peri-implant tissues increased after one year, and there was a significant difference in all compared time periods. The mean pink esthetic score was 8.07.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Stefan Fickl, Annika Therese Kroger, Thomas Dietrich, Moritz Kebschull
Summary: This systematic review found that soft tissue augmentation procedures inconsistently affected marginal bone level changes, but consistently improved secondary outcomes. The combination of soft and hard tissue augmentation showed better results in terms of marginal soft tissue recession compared to hard tissue augmentation alone. Contour augmentations with soft or hard tissue augmentation resulted in comparable marginal bone level changes.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ronald E. Jung, Marionna N. Kovacs, Daniel S. Thoma, Christoph H. F. Hammerle
Summary: The long-term outcomes of implants placed in conjunction with guided bone regeneration (GBR) with or without recombinant human bone morphogenetic protein-2 (rhBMP-2) were assessed. The study showed that after at least 17 years, the implant survival rate was 100% and the clinical and radiographic results were excellent.
CLINICAL ORAL IMPLANTS RESEARCH
(2022)
Article
Polymer Science
Igor S. Brum, Carlos N. Elias, Jorge J. de Carvalho, Jorge L. S. Pires, Mario J. S. Pereira, Ronaldo S. de Biasi
Summary: Dental implant treatment requires sufficient bone volume in the site for mechanical stability; when insufficient, surgical techniques like GBR are necessary. Resorbable collagen type I membranes were manufactured for GBR, showing no cytotoxicity and high biocompatibility in both in vitro and in vivo tests. This membrane could be a suitable choice for GBR procedures.
Review
Dentistry, Oral Surgery & Medicine
Istvan Urban, Eduardo Montero, Ignacio Sanz-Sanchez, David Palombo, Alberto Monje, Grazia Tommasato, Matteo Chiapasco
Summary: Vertical ridge augmentation is a challenging procedure in implant dentistry due to the advanced skills required and the difficulties associated with bone augmentation outside the bony contour. The management of flap closure often leads to complications such as swelling and hematomas. New techniques and biomaterials have been developed to reduce invasiveness and complications in vertical ridge augmentation, including diagnostic/treatment planning considerations, surgical techniques, and digital tools.
PERIODONTOLOGY 2000
(2023)
Article
Dentistry, Oral Surgery & Medicine
Alessandro Cucchi, Elisabetta Vignudelli, Antonino Fiorino, Gerardo Pellegrino, Giuseppe Corinaldesi
Summary: The study aimed to evaluate hard and soft tissues around implants in the posterior mandible 1 year after vertical ridge augmentation. The results showed that the GBR treatment with titanium meshes plus collagen membranes did not have significant differences in peri-implant bone level change compared to reinforced PTFE membranes. Both groups demonstrated stable hard and soft tissues after 1 year of follow-up.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Eun-Hee Jung, Seong-Nyum Jeong, Jae-Hong Lee
Summary: The study found that L- and I-shaped DBBM-C were more beneficial in terms of horizontal augmentation stability compared to DBBM after a 5-month healing period in peri-implant dehiscence defects. Early postoperative discomfort, wound healing outcomes, and periotest values did not differ significantly between the different groups.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Yin-Zhe An, Franz-Josef Strauss, Jin-Young Park, Yu Qin Shen, Daniel Stefan Thoma, Jung-Seok Lee
Summary: The results of the study suggest that fixation of collagen membrane (CM) significantly enhances the expression of osteogenic factors, leading to more new bone formation, which is important in guiding bone regeneration.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Luca Sbricoli, Gennaro Cecoro, Claudio Leone, Livia Nastri, Riccardo Guazzo, Luigi Guida, Marco Annunziata
Summary: The study found that mildly acid-etched Ti implant surfaces showed significantly higher bacterial adhesion compared to turned surfaces, and grade 5 disks exhibited higher bacterial adhesion than grade 4 disks, indicating that bacterial adhesion is sensitive to both Ti surface topography and composition.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Multidisciplinary
Livia Nastri, Ludovica Nucci, Domenico Carozza, Stefano Martina, Ismene Serino, Letizia Perillo, Fabrizia d'Apuzzo, Vincenzo Grassia
Summary: The study aimed to evaluate gingival recessions and periodontal status in patients who underwent non-extraction orthodontic treatment and retention for at least two years. The findings suggest that non-extraction orthodontic treatment does not have a significant impact on the development of gingival recessions or periodontal health after retention.
APPLIED SCIENCES-BASEL
(2022)
Review
Chemistry, Physical
Luigi Guida, Eriberto Bressan, Gennaro Cecoro, Armando Davide Volpe, Massimo Del Fabbro, Marco Annunziata
Summary: This systematic review and meta-analysis found that short implants perform as well as longer implants in edentulous sites without the need for bone augmentation. The survival rate of short implants is similar to that of longer implants, but longer implants experience more bone loss at 1 and 5 years, while short implants have more technical complications at 10 years.
Review
Chemistry, Multidisciplinary
Gennaro Cecoro, Debora Bencivenga, Marco Annunziata, Nunzio Cennamo, Fulvio Della Ragione, Alessandro Formisano, Angelantonio Piccirillo, Emanuela Stampone, Pio Antonio Volpe, Luigi Zeni, Adriana Borriello, Luigi Guida
Summary: This scoping review evaluates the influence of magnetic field stimulation on dental implant osseointegration. In vitro studies show a positive effect of Pulsed ElectroMagnetic Fields (PEMF) on bone cell proliferation, while the effects of Static magnetic Fields from permanent Magnets (SFM) are conflicting. Both types of stimulation induce cell adhesion and osteogenic differentiation. In vivo studies demonstrate increased bone-to-implant contact rate and positive effects on implant stability. However, further preclinical and clinical studies are needed to assess the effect of magnetic fields on dental implant osseointegration more clearly.
APPLIED SCIENCES-BASEL
(2022)
Article
Environmental Sciences
Luca Sbricoli, Lia Bernardi, Fatima Ezeddine, Christian Bacci, Adolfo Di Fiore
Summary: This study investigated oral hygiene knowledge in a sample of adolescents, with a particular focus on those wearing orthodontic braces. The findings revealed that the majority of respondents brushed their teeth at least twice a day, but only a small percentage used dental floss daily. It was also found that few participants wearing orthodontic braces received professional oral hygiene treatment, and most adolescents learned about oral hygiene from their parents.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Luca Sbricoli, Sara Ricci, Andrea Cattozzo, Riccardo Favero, Eriberto Bressan, Stefano Sivolella
Summary: This study presents a novel technique that combines surgical and orthodontic approaches to retrieve impacted second molars. The technique involves extraction of the third molar, placement of a distally positioned screw, and the use of a coil spring to connect the screw to the second molar. The results show successful repositioning of impacted second molars with minimal complications.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Luigi Guida, Umberto Esposito, Massimiliano Sirignano, Paolo Torrisi, Marco Annunziata, Denis Cecchinato
Summary: The aim of this multicenter trial was to compare the effectiveness of 6mm short and 11mm long implants for the rehabilitation of completely edentulous non-atrophic mandibles. The study found that there was no significant difference in clinical and radiographic outcomes between the two types of implants when used in similar conditions.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Chemistry, Physical
Francesco Pera, Paolo Pesce, Francesco Bagnasco, Nicolo Pancini, Massimo Carossa, Lorenzo Baldelli, Marco Annunziata, Marco Migliorati, Domenico Baldi, Maria Menini
Summary: The aim of this study was to compare the accuracy of a new digital impression system with the traditional plaster impression technique in the realization of full-arch implant-supported metal frameworks. The results showed that the accuracy of the metal frameworks obtained through the digital impression system was comparable to those obtained through the traditional plaster impression technique. This is significant for promoting the clinical application of digital impression systems.
Article
Chemistry, Multidisciplinary
Roberto Sorrentino, Maria I. Di Mauro, Renato Leone, Gennaro Ruggiero, Marco Annunziata, Fernando Zarone
Summary: The study evaluated the long-term clinical performance of narrow diameter implants and different types of crowns in the treatment of maxillary lateral incisors agenesis. Marginal bone resorption and soft tissue quality were evaluated after 16 years. The overall success and survival rates of the restorations were 85% and 95% respectively, with no significant differences between metal-ceramic and all-ceramic crowns.
APPLIED SCIENCES-BASEL
(2023)
Article
Chemistry, Analytical
Nunzio Cennamo, Angelantonio Piccirillo, Debora Bencivenga, Francesco Arcadio, Marco Annunziata, Fulvio Della Ragione, Luigi Guida, Luigi Zeni, Adriana Borriello
Summary: Point-of-Care (POC) tests based on biomarkers are crucial for advancing medicine, especially in monitoring acute and chronic inflammations. Among the pro-inflammatory cytokines, interleukin 6 (IL-6) is considered one of the most important. This study presents the development of two IL-6 biosensors using a combination of the same antibody self-assembled monolayer and two different plasmonic probes. Experimental results show that these biosensors can detect IL-6 in different concentration ranges. The proposed sensing approach has the potential to be used in POC devices for diagnosing and monitoring oral and systemic diseases by detecting IL-6 in the desired concentration range.
Article
Engineering, Biomedical
Aishwarya Bal, Saurav Panda, Rinkee Mohanty, Anurag Satpathy, Rashmita Nayak, Margherita Tumedei, Francesca Argenta, Gianluca Colapinto, Massimo Del Fabbro, Marco Annunziata
Summary: The effectiveness of hyaluronic acid (HA) gel injection with and without plasma rich in growth factors (PRGF) for managing interdental papillary loss was evaluated in this study. The results showed significant improvement in PW, PDH, DA, and DV in both groups, with HA + PRGF group showing significantly greater improvement in PDH, DA, and DV at 6 and 12 weeks compared to HA group. Therefore, PRGF may have a significant adjuvant effect when used along with HA.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Luigi Guida, Debora Bencivenga, Marco Annunziata, Francesco Arcadio, Adriana Borriello, Fulvio Della Ragione, Alessandro Formisano, Angelantonio Piccirillo, Luigi Zeni, Nunzio Cennamo
Summary: In this study, a novel optical fiber biosensor based on surface plasmon resonance was developed to detect salivary MMP-8 protein. The biosensor had a low detection limit in both buffer and saliva, and showed high selectivity. This technology has the potential to be a highly sensitive biosensor for monitoring salivary MMP-8 levels.
JOURNAL OF DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Marco Annunziata, Giovanna Donnarumma, Agostino Guida, Livia Nastri, Gerardo Persico, Alessandra Fusco, Ignacio Sanz-Sanchez, Luigi Guida
Summary: The objective of this randomized clinical trial was to evaluate the efficacy of repeated ICG-aPDT as an adjunct to full-mouth subgingival debridement in treating periodontitis. The study found that the combination of repeated ICG-aPDT and full-mouth subgingival debridement did not provide significant benefits compared to debridement alone, except for selective clinical and microbiological improvements.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Engineering, Biomedical
Livia Nastri, Ludovica Nucci, Vincenzo Grassia, Rino Miraldi
Summary: The study found that both ASC crowns and CC crowns in single tooth implant restorations can achieve high levels of white and pink esthetic scores, which are maintained over time without any signs of peri-implant diseases or bone loss, regardless of the choice of connection.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2021)
