Organocatalytic asymmetric N-sulfonyl amide C-N bond activation to access axially chiral biaryl amino acids

Triflamides: Highly Reactive, Electronically Activated N-Sulfonyl Amides in Catalytic N–C(O) Amide Cross-Coupling

(2019) Shicheng Shi et al.   ORGANIC LETTERS

Facile Synthesis of 2,2-Diacyl Spirocyclohexanones via an N-Heterocyclic Carbene-Catalyzed Formal [3C + 3C] Annulation

(2019) Yaru Gao et al.   ORGANIC LETTERS

Access to Enantioenriched Organosilanes from Enals and β-Silyl Enones: Carbene Organocatalysis

(2018) Yuxia Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbene-catalyzed aerobic oxidation of isoquinolinium salts: efficient synthesis of isoquinolinones

(2018) Guanjie Wang et al.   GREEN CHEMISTRY

Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann’s Lactones with Molecular H2

(2018) Gen-Qiang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Suzuki–Miyaura Coupling of Aliphatic Amides

(2018) Timothy B. Boit et al.   ACS Catalysis

Enhanced Reactivity by Torsional Strain of Cyclic Diaryliodonium in Cu-Catalyzed Enantioselective Ring-Opening Reaction

(2018) Kun Zhao et al.   Chem

Design of Chiral Bifunctional Dialkyl Sulfide Catalysts for Regio-, Diastereo-, and Enantioselective Bromolactonization

(2018) Ryuichi Nishiyori et al.   CHEMISTRY-A EUROPEAN JOURNAL

Acyl and Decarbonylative Suzuki Coupling of N-Acetyl Amides: Electronic Tuning of Twisted, Acyclic Amides in Catalytic Carbon–Nitrogen Bond Cleavage

(2018) Chengwei Liu et al.   ACS Catalysis

Carbene-Catalyzed Construction of Carbazoles from Enals and 2-Methyl-3-oxoacetate Indoles

(2018) Dehai Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Amide Activation in Ground and Excited States

(2018) Ervin Kovács et al.   MOLECULES

Heteroatom Substitution at Amide Nitrogen—Resonance Reduction and HERON Reactions of Anomeric Amides

(2018) Stephen Glover et al.   MOLECULES

Palladium/NHC (NHC = N-Heterocyclic Carbene)-Catalyzed B-Alkyl Suzuki Cross-Coupling of Amides by Selective N–C Bond Cleavage

(2018) Guangrong Meng et al.   ORGANIC LETTERS

Palladium-Catalyzed Suzuki–Miyaura Coupling of Aryl Esters

(2017) Taoufik Ben Halima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Visible-Light Photoredox/Nickel-Catalyzed Synthesis of Aliphatic Ketones via N–C Cleavage of Imides

(2017) Javad Amani et al.   ORGANIC LETTERS

Ni-Catalyzed Reductive Cross-Coupling of Amides with Aryl Iodide Electrophiles via C–N Bond Activation

(2017) Shengyang Ni et al.   ORGANIC LETTERS

Access to Amide from Aldimine via Aerobic Oxidative Carbene Catalysis and LiCl as Cooperative Lewis Acid

(2017) Guanjie Wang et al.   ORGANIC LETTERS

Palladium-Catalyzed Suzuki–Miyaura Cross-Coupling of N-Mesylamides by N–C Cleavage: Electronic Effect of the Mesyl Group

(2017) Chengwei Liu et al.   ORGANIC LETTERS

Nickel-catalyzed transamidation of aliphatic amide derivatives

(2017) Jacob E. Dander et al.   Chemical Science

Suzuki–Miyaura cross-coupling of amides and esters at room temperature: correlation with barriers to rotation around C–N and C–O bonds

(2017) Peng Lei et al.   Chemical Science

Nickel-catalysed retro-hydroamidocarbonylation of aliphatic amides to olefins

(2017) Jiefeng Hu et al.   Nature Communications

Breaking Amides using Nickel Catalysis

(2017) Jacob E. Dander et al.   ACS Catalysis

Nickel-Catalyzed Esterification of Aliphatic Amides

(2016) Liana Hie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Biaryls through Nickel-Catalyzed Suzuki-Miyaura Coupling of Amides by Carbon-Nitrogen Bond Cleavage

(2016) Shicheng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Decarbonylative Borylation of Amides: Evidence for Acyl C−N Bond Activation

(2016) Jiefeng Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantiodivergent Atroposelective Synthesis of Chiral Biaryls by Asymmetric Transfer Hydrogenation: Chiral Phosphoric Acid Catalyzed Dynamic Kinetic Resolution

(2016) Keiji Mori et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Activation of Acyl C−O Bonds of Methyl Esters

(2016) Liana Hie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent developments in the synthesis and utilization of chiral β-aminophosphine derivatives as catalysts or ligands

(2016) Wenbo Li et al.   CHEMICAL SOCIETY REVIEWS

Dynamic Kinetic Resolution of Biaryl Lactones via a Chiral Bifunctional Amine Thiourea-Catalyzed Highly Atropo-enantioselective Transesterification

(2016) Chenguang Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis

(2016) Emma L. Baker et al.   Nature Communications

Nickel-Catalyzed Deamidative Step-Down Reduction of Amides to Aromatic Hydrocarbons

(2016) Aniruddha Dey et al.   ACS Catalysis

Chiral Monophosphorus Ligands for Asymmetric Catalytic Reactions

(2016) Wenzhen Fu et al.   ACS Catalysis

Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules

(2015) Stefan A. Ruider et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

General Olefin Synthesis by the Palladium-Catalyzed Heck Reaction of Amides: Sterically Controlled Chemoselective NC Activation

(2015) Guangrong Meng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acylative Suzuki coupling of amides: acyl-nitrogen activation via synergy of independently modifiable activating groups

(2015) Xijing Li et al.   CHEMICAL COMMUNICATIONS

Stronger Brønsted Acids: Recent Progress

(2015) Takahiko Akiyama et al.   CHEMICAL REVIEWS

Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds

(2015) Liana Hie et al.   NATURE

Nickel-catalysed Suzuki–Miyaura coupling of amides

(2015) Nicholas A. Weires et al.   Nature Chemistry

P,N ligands in asymmetric catalysis

(2013) Michael P. Carroll et al.   CHEMICAL SOCIETY REVIEWS

Solvent-Free Enantioselective Friedländer Condensation with Wet 1,1′-Binaphthalene-2,2′-diamine-Derived Prolinamides as Organocatalysts

(2013) Abraham Bañón-Caballero et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

Low-loading asymmetric organocatalysis

(2011) Francesco Giacalone et al.   CHEMICAL SOCIETY REVIEWS

Revealing Atropisomer Axial Chirality in Drug Discovery

(2011) Steven R. LaPlante et al.   ChemMedChem

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

Synthesis of Axially Chiral Amino Acid and Amino Alcohols via Additive−Ligand-Free Pd-Catalyzed Domino Coupling Reaction and Subsequent Transformations of the Product Amidoaza[5]helicene

(2010) Takumi Furuta et al.   JOURNAL OF ORGANIC CHEMISTRY

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

(Thio)urea organocatalysis—What can be learnt from anion recognition?

(2009) Zhiguo Zhang et al.   CHEMICAL SOCIETY REVIEWS

Chiral Diphosphine and Monodentate Phosphorus Ligands on a Spiro Scaffold for Transition-Metal-Catalyzed Asymmetric Reactions

(2008) Jian-Hua Xie et al.   ACCOUNTS OF CHEMICAL RESEARCH

Amidicity Change as a Significant Driving Force and Thermodynamic Selection Rule of Transamidation Reactions. A Synergy between Experiment and Theory

(2008) Zoltán Mucsi et al.   JOURNAL OF PHYSICAL CHEMISTRY B