Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income

Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life

(2019) W. David Hill et al.   MOLECULAR PSYCHIATRY

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

(2019) Andrew D. Grotzinger et al.   Nature Human Behaviour

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

(2019) Max Lam et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic correlates of social stratification in Great Britain

(2019) Abdel Abdellaoui et al.   Nature Human Behaviour

Evaluating the potential role of pleiotropy in Mendelian randomization studies

(2018) Gibran Hemani et al.   HUMAN MOLECULAR GENETICS

Genomic analysis of family data reveals additional genetic effects on intelligence and personality

(2018) W. David Hill et al.   MOLECULAR PSYCHIATRY

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence

(2018) W. D. Hill et al.   MOLECULAR PSYCHIATRY

Genetic identification of brain cell types underlying schizophrenia

(2018) Nathan G. Skene et al.   NATURE GENETICS

Multi-trait analysis of genome-wide association summary statistics using MTAG

(2018) Patrick Turley et al.   NATURE GENETICS

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

(2018) Hilary K. Finucane et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Using nature to understand nurture

(2018) Philipp D. Koellinger et al.   SCIENCE

The nature of nurture: Effects of parental genotypes

(2018) Augustine Kong et al.   SCIENCE

Comment on ‘Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets’ by Lam et al.

(2018) W. David Hill   Twin Research and Human Genetics

Causal associations between risk factors and common diseases inferred from GWAS summary data

(2018) Zhihong Zhu et al.   Nature Communications

ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci

(2018) David Stacey et al.   NUCLEIC ACIDS RESEARCH

An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings

(2018) Eleanor Sanderson et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

A Further Comment on ‘Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets’ by Lam et al.

(2018) W. D. Hill   Twin Research and Human Genetics

Collider scope: when selection bias can substantially influence observed associations

(2017) Marcus R Munafò et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Negative control exposure studies in the presence of measurement error: implications for attempted effect estimate calibration

(2017) Eleanor Sanderson et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors

(2017) Emanuele Di Angelantonio et al.   LANCET

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium

(2017) J W Trampush et al.   MOLECULAR PSYCHIATRY

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

(2017) Steven Gazal et al.   NATURE GENETICS

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

(2017) Michelle Luciano et al.   NATURE GENETICS

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

(2017) Louise V Wain et al.   NATURE GENETICS

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

(2017) Daniel J Weiner et al.   NATURE GENETICS

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Orienting the causal relationship between imprecisely measured traits using GWAS summary data

(2017) Gibran Hemani et al.   PLoS Genetics

Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies

(2016) Philip C Haycock et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Age-Dependent Pleiotropy Between General Cognitive Function and Major Psychiatric Disorders

(2016) W. David Hill et al.   BIOLOGICAL PSYCHIATRY

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

(2016) William J. Astle et al.   CELL

Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank

(2016) W. David Hill et al.   CURRENT BIOLOGY

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Genome-wide association study identifies 74 loci associated with educational attainment

(2016) Aysu Okbay et al.   NATURE

Detection and interpretation of shared genetic influences on 42 human traits

(2016) Joseph K Pickrell et al.   NATURE GENETICS

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

The statistical properties of gene-set analysis

(2016) Christiaan A. de Leeuw et al.   NATURE REVIEWS GENETICS

A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome

(2016) Anthony D. Schmitt et al.   Cell Reports

Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions

(2016) W D Hill et al.   Translational Psychiatry

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

Gene expression analysis identifies global gene dosage sensitivity in cancer

(2015) Rudolf S N Fehrmann et al.   NATURE GENETICS

The Reactome pathway Knowledgebase

(2015) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Biological interpretation of genome-wide association studies using predicted gene functions

(2015) Tune H. Pers et al.   Nature Communications

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Socioeconomic status. The relationship with health and autoimmune diseases

(2014) Omar-Javier Calixto et al.   AUTOIMMUNITY REVIEWS

PRSice: Polygenic Risk Score software

(2014) Jack Euesden et al.   BIOINFORMATICS

Genetic variability in the regulation of gene expression in ten regions of the human brain

(2014) Adaikalavan Ramasamy et al.   NATURE NEUROSCIENCE

Quality control and conduct of genome-wide association meta-analyses

(2014) Thomas W Winkler et al.   Nature Protocols

Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

(2014) W D Hill et al.   Translational Psychiatry

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

(2013) C. A. Rietveld et al.   SCIENCE

Cohort Profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness

(2012) Blair H Smith et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

A Versatile Gene-Based Test for Genome-wide Association Studies

(2010) Jimmy Z. Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE