Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

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New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

(2019) Nick Shrine et al.   NATURE GENETICS

PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations

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NRF2 and the Hallmarks of Cancer

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Cutting Edge: Piezo1 Mechanosensors Optimize Human T Cell Activation

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Cigarette Smoke–Induced Emphysema Exhausts Early Cytotoxic CD8+T Cell Responses against Nascent Lung Cancer Cells

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Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

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Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

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Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation

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Gene expression profiling of asthma phenotypes demonstrates molecular signatures of atopy and asthma control

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Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy

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An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

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Integrative analysis of 111 reference human epigenomes

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Genetic studies of body mass index yield new insights for obesity biology

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Partitioning heritability by functional annotation using genome-wide association summary statistics

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Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

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The Novel Protein Suppressed in Lung Cancer Down-Regulated in Lung Cancer Tissues Retards Cell Proliferation and Inhibits the Oncokinase Aurora-A

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Chromosome 4q31 locus in COPD is also associated with lung cancer

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Genome-wide meta-analyses identify multiple loci associated with smoking behavior

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Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

COPD prevalence is increased in lung cancer, independent of age, sex and smoking history

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Lung function predicts lung cancer risk in smokers: a tool for targeting screening programmes

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Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

Common variants at five new loci associated with early-onset inflammatory bowel disease

(2009) Marcin Imielinski et al.   NATURE GENETICS

Widespread Genomic Signatures of Natural Selection in Hominid Evolution

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