期刊
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
卷 123, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2019.115763
关键词
Chiral recognition; Mass spectrometry; Kinetic method; Chiral recognition ratio method; Photodissociation mass spectrometry; Ion mobility mass spectrometry
资金
- National Natural Science Foundation of China [81874306]
- Hong Kong Research Grants Council [153040/15P, 153348/16P, 153041/17P, C5031-14E, C4002-17G, R4005-18]
- University Research Facility in Chemical and Environmental Analysis of The Hong Kong Polytechnic University
- University Research Facility in Life Sciences of The Hong Kong Polytechnic University
Chiral analysis by mass spectrometry has attracted much attention due to its advantages in speed, sensitivity and specificity. In this review, recent advances in chiral analysis by mass spectrometry are summarized, with the methods based on tandem mass spectrometry (e.g., kinetic method, chiral recognition ratio method and photodissociation mass spectrometry method) and ion mobility mass spectrometry highlighted. Different methods are compared, and the limitations of the current studies and the prospects of chiral mass spectrometry are discussed. (C) 2019 Elsevier B.V. All rights reserved.
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