Review
Chemistry, Inorganic & Nuclear
Xiaojing Nan, Yuchen Huyan, Hongjuan Li, Shiguo Sun, Yongqian Xu
Summary: Transition metal ions play crucial roles in medicine, life sciences, and environmental science, but some like mercury, copper, and iron ions pose serious health and environmental risks due to biomagnification. Monitoring metal ion levels in organisms and the environment is urgent, and reaction-based fluorescent probes offer higher sensitivity and selectivity than traditional methods. Research on these probes for Hg2+, Cu2+, and Fe2+/Fe2+ detection has advanced in the past decade, with potential for interdisciplinary development in the future.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Polymer Science
Yanyun He, Fan Ding, Yan Zhao, Wei Tian, Weixu Feng, Hongxia Yan
Summary: This study successfully synthesized two linear polysiloxanes with multicolor fluorescence through a one-pot transesterification method. The multicolor emission is attributed to the local conjugation chain formed by silicon-oxygen bond. Additionally, the polymers also exhibit multiple stimuli-responsive properties.
Article
Spectroscopy
Wen Chen, Xiaoping Lin, Xin Yin, Xuanyuan Wang, Dan Xie, Wenqing Tang, Cong Dai, Rongying Zeng, Mengqin Liu
Summary: In this study, an aggregation-induced emission (AIE) fluorescent probe has been designed for the highly sensitive and selective detection of Hg2+. The probe demonstrates outstanding detectivity and hypersensitivity for Hg2+ in aqueous solutions, and shows potential applications in environmental, food, and biological systems.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Yanru Huang, Ying Li, Yang Li, Keli Zhong, Lijun Tang
Summary: In this study, a benzothiazole derived fluorescent probe based on the AIE + ESIPT mechanism was developed for the rapid detection of mercury ion (Hg2+). The probe showed excellent selectivity, good anti-interference ability, low detection limit (2.85 x 10(-9) M), and a large Stokes shift (170 nm) in a DMF/H2O mixture solution. The practical application evaluation confirmed its effectiveness in live cell imaging, natural water, and seafood samples for precise determination of Hg2+.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yuan-Jun Tong, Lu-Dan Yu, Nan Li, Qi Fu, Ke Xu, Jiajun Wei, Yu-Xin Ye, Jianqiao Xu, Fang Zhu, Janusz Pawliszyn, Gangfeng Ouyang
Summary: A new strategy for designing a multipurpose ratiometric probe is presented in this study, which can detect the presence of mercury and fluoride ions simultaneously, establishing a successful on-site water monitoring method.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Physical
Li Huang, Yucheng Sun, Guozhi Zhao, Lizhen Wang, Xia Meng, Jianhua Zhou, Hongdong Duan
Summary: A new type of green fluorescence sensor FLN based on fluorescein-carbazole was developed in this study for efficient detection of trace mercury in environmental and biological samples. FLN demonstrated high sensitivity and low toxicity, making it a promising tool for mercury detection in living cells.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Analytical
Kaiqi Liu, Luminita Marin, Xinjian Cheng
Summary: Fluorescent beta-cyclodextrin (beta-CD) based probes containing naphthalimide group were synthesized to specifically recognize Hg2+/Hg+ in aqueous systems. The probes exhibit enhanced fluorescence intensity when binding with Hg2+/Hg+, and the hydrophobic parts of the probes form special micelle-like structures due to complexation with Hg2+/Hg+. The probes have the potential for detecting Hg2+/Hg+ in aqueous solutions without the use of organic solvents.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Multidisciplinary
Jin-jin Tian, Dian-dian Deng, Long Wang, Zhao Chen, Shouzhi Pu
Summary: A tetraphenylethene-modified rhodanine derivative was designed and synthesized, exhibiting excellent fluorescence properties and multiple applications such as aggregation-induced emission enhancement, solvatochromic fluorescence effect, reversible mechanochromic fluorescence behavior, and sensitive detection of Hg2+.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Yongkang Yao, Peng Ding, Chenxu Yan, Yining Tao, Bo Peng, Weimin Liu, Junyou Wang, Martien A. Cohen A. Stuart, Zhiqian Guo
Summary: The combination of photothermal therapy (PTT) and magnetic resonance imaging (MRI) can be achieved by using polyelectrolyte nanoassemblies (APN) strategy, which provides a soft inner microenvironment and enhances intramolecular motion and magnetic relaxation. This strategy enables fluorescence lifetime imaging of tumor spheroids and spatio-temporal MRI-guided high-efficient PTT.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Organic
Su-qian Cai, Ke-feng Zhang, Xiao-hua Cai
Summary: In this paper, a fluorescent probe L based on 2-hydroxy-1-naphthaldehyde derivative was synthesized for highly selective and sensitive detection of Hg2+. The probe exhibited aggregation-induced emission properties and could be used to detect Hg2+ in an aqueous solution of DMSO/H2O. It also showed advantages such as low-cost, structural stability, high water solubility, rapid response, and potential application in traditional Chinese medicine.
TETRAHEDRON LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Yongxin Pan, Yuetian Guo, Ying Li, Lijun Tang, Xiaomei Yan
Summary: In this study, a simple fluorescent probe TPE-Hg based on aggregation-induced emission mechanism was synthesized for rapid and accurate detection of Hg2 + in water samples, cells, and food. The method shows fast response, strong anti-interference ability, and low detection limit.
CHINESE CHEMICAL LETTERS
(2023)
Article
Biochemistry & Molecular Biology
Dongmi Li, Panpan Lv, Xiao-Wen Han, Zhilei Jia, Min Zheng, Hai-Tao Feng
Summary: A simple tetraphenylethene (TPE) derivative with aggregation-induced emission (AIE) characteristics was synthesized and used as a fluorescent sensor for the detection of nitrophenolic explosives with high selectivity. The sensor could identify nitroaromatic compounds in water solution and solid state, and only hydroxyl-containing nitrophenolic explosives caused fluorescence quenching. The sensing mechanism was investigated using fluorescence titration and H-1 NMR spectra. This AIE-active probe has the potential to be applied in the development of portable explosive detection devices.
Article
Chemistry, Analytical
Muthusamy Selvaraj, Kanagaraj Rajalakshmi, Dae-Hwan Ahn, Su-Jin Yoon, Yun-Sik Nam, Yeonhee Lee, Yuanguo Xu, Jong-Won Song, Kang-Bong Lee
Summary: A novel TPE derivative, TPE-BTA, was designed and synthesized with comprehensive aggregation-induced emission properties for efficient detection of mercury ions with high sensitivity and selectivity.
ANALYTICA CHIMICA ACTA
(2021)
Article
Spectroscopy
Jie Zhao, Jiawei Zhang, Baojun Hu, Chunyu Gao, Zan Li, Zhiwei Sun, Jinmao You
Summary: A new ratiometric fluorescent probe (APS-NA) was designed and synthesized for the detection of mercury ions in the environment and multiple biological samples. The probe shows a large Stokes shift, high selectivity, high sensitivity and naked eye visualization.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Sumita Subedi, Lok Nath Neupane, Hyeongseok Yu, Keun-Hyeung Lee
Summary: A highly selective ratiometric fluorescent chemodosimeter was synthesized for the detection of Hg2+, which showed remarkable detection properties including high selectivity and sensitivity, large fluorescent signal changes, and well-operation in aqueous solutions. The displacement reaction between phenylboronic acid and Hg2+ ions provided a covalent adduct of mercury ion, leading to significant fluorescent signal changes when aggregated in aqueous solution. With a low detection limit of 15.2 nM, nanomolar concentrations of Hg2+ could be successfully detected, providing a ratiometric fluorescent detection method for quantifying low levels of Hg2+ in groundwater and tap water samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Optics
Hao Zhang, Jiajian You, Chen Nie, Jiahui Wang, Xuezhe Dong, Ruifang Guan, Duxia Cao, Qifeng Chen
JOURNAL OF LUMINESCENCE
(2019)
Article
Chemistry, Physical
Qifeng Chen, Hui Wang, Cuicui Wang, Ruifang Guan, Ran Duan, Yanfen Fang, Xun Hu
APPLIED CATALYSIS B-ENVIRONMENTAL
(2020)
Article
Engineering, Environmental
Qifeng Chen, Hui Wang, Qingrui Luan, Ran Duan, Xingzhong Cao, Yanfen Fang, Delong Ma, Ruifang Guan, Xun Hu
JOURNAL OF HAZARDOUS MATERIALS
(2020)
Article
Chemistry, Multidisciplinary
Qingrui Luan, Qifeng Chen, Jie Zheng, Ruifang Guan, Yanfen Fang, Xun Hu
Article
Chemistry, Physical
Qifeng Chen, Keyan Wang, Guoming Gao, Jinzhi Ren, Ran Duan, Yanfen Fang, Xun Hu
Summary: The study demonstrates that controlling the surface defect engineering and nanoalloy modification of nano-composite photocatalysts can enhance photocatalytic activity.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Physical
Huailin Fan, Xun Hu, Shu Zhang, Zhixiang Xu, Guoming Gao, Yan Zheng, Guangzhi Hu, Qifeng Chen, Tahani Saad AlGarni, Rafael Luque
Summary: By utilizing the spheroidizing growth of hydrothermal carbon as an assembly drive and in situ formed melamine cyanurate nanosheets as a structure-directing agent, a promising B, N, and O co-doped carbon flower was successfully designed and assembled for the cathode of Zn2+ hybrids supercapacitors, showing excellent performance.
Article
Nanoscience & Nanotechnology
Qifeng Chen, Guoming Gao, Huailin Fan, Jie Zheng, Lulu Ma, Yanyu Ding, Yanfen Fang, Ran Duan, Xiaofeng Cao, Yanchuan Guo, Dongge Ma, Xun Hu
Summary: The surface properties of a photocatalyst, such as surface acid sites and oxygen vacancies, are crucial for photocatalytic organic synthesis reactions. In this study, a green photocatalytic approach for the selective synthesis of benzoin isopropyl ether (BIE) over WO3 was reported, driven by a green-light-emitting diode. The improved photocatalytic activity was attributed to the synergy between oxygen vacancies and acid sites over N-doped WO3 nanobelts. The results showed that reactant molecules were mainly adsorbed and activated on the surface oxygen vacancies, while the Bronsted acid promoted the etherification reaction. The introduction of oxygen vacancies and nitrogen altered the band structure and electronic properties, leading to improved photocatalytic activity.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Baosheng Ren, Qingrui Luan, LuLu Ma, Yanyu Ding, Dongge Ma, Xiaofeng Cao, Yanchuan Guo, Ruifang Guan, Qifeng Chen
Summary: The light absorption capacity and charge carrier separation are important factors in the photocatalytic hydrogen evolution activity. Metal sulfides with solid solution and heterojunctions are effective ways to enhance the separation efficiency. The Zn1-xCrxIn2S4 solid solution photocatalysts showed enhanced activity due to the LSPR effect and interfacial charge transfer. They exhibited 2.2 times higher activity compared to ZnIn2S4.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Agricultural Engineering
Cong Ming, Yuchen Jiang, Chao Li, Qifeng Chen, Shu Zhang, Shuang Wang, Bin Li, Zhenhua Cui, Yonggui Tang, Xun Hu
Summary: CO2 and H2O are important activators in the production of activated carbon (AC) via physical activation method. The activation with H2O leads to higher weight loss and more developed pore structures, while the activation with CO2 results in AC with more oxygen-containing functionalities and main micropores. H2O shows superior capability for adsorption of phenol. The life cycle analysis (LCA) suggests that CO2 activation has lower environmental impact.
BIOMASS & BIOENERGY
(2023)
Article
Engineering, Environmental
Qifeng Chen, Guoming Gao, Hongpian Guo, Shen-Ao Wang, Qingqing Wang, Yanfen Fang, Xun Hu, Ran Duan
Summary: This work provides an avenue for the synthesis of metal-free photocatalysts with improved overall water-splitting activity through the combination of heterogeneous atom doping and construction of delocalized & pi;-conjugated structures and polar group modification.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Materials Science, Multidisciplinary
Jie Zheng, Shuaitao Li, Yuanrong Zhang, Peng Zheng, Xun Hu, Yanfen Fang, Ran Duan, Qifeng Chen
Summary: The conversion of CO2 into high-value-added chemicals through photocatalysis is significant. Ceria (CeO2) has been extensively studied for this purpose, but its surface oxygen vacancies (V(O)s) are unstable. This study found that the coordination of highly dispersed Ag species can stabilize the V(O)s of CeO2, allowing for selective photocatalytic CO2 conversion. The synergy between Ag species and V(O)s promotes the adsorption, activation, and selectivity of CO2 molecules, leading to enhanced photocatalytic activity.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Materials Science, Multidisciplinary
Guoming Gao, Ximeng Wang, Qifeng Chen, Caibo Xie, Jie Zheng, Huailin Fan, Lulu Ma, Ruifang Guan, Yanfen Fang, Xun Hu
Summary: The study showed that the photocatalytic activity of surface fluorinated TiO2 nanosheets is influenced by F-S, V-O, and acidic sites, with the synergistic effect of F-S and adjacent V-O boosting charge carrier separation efficiency and enhancing photocatalytic activity.
JOURNAL OF MATERIALS CHEMISTRY C
(2021)
Article
Chemistry, Physical
Guoming Gao, Yuewen Shao, Yong Gao, Tao Wei, Guanggang Gao, Shu Zhang, Yi Wang, Qifeng Chen, Xun Hu
Summary: This study introduced phosphorus to modify the properties of the catalyst, facilitating the conversion of furfural to cyclopentanone. The reaction of phosphorus with alumina and metallic nickel led to the formation of AlPO4 phase and nickel phosphide species, increasing acidic sites abundance and tailoring the selectivity of hydrogenation sites. The balanced distribution of hydrogenation sites and acidic sites was crucial for the selective conversion of furfural to cyclopentanone.
CATALYSIS SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Physical
Guoming Gao, Mingxuan Lv, Yuewen Shao, Guanggang Gao, Hui Zhao, Shu Zhang, Yi Wang, Ran Duan, Qifeng Chen, Xun Hu
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2020)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).