Measures of 6-mercaptopurine and methotrexate maintenance therapy intensity in childhood acute lymphoblastic leukemia

Maintenance therapy of childhood acute lymphoblastic leukemia revisited-Should drug doses be adjusted by white blood cell, neutrophil, or lymphocyte counts?

(2016) Kjeld Schmiegelow et al.   PEDIATRIC BLOOD & CANCER

Mercaptopurine metabolite levels are predictors of bone marrow toxicity following high-dose methotrexate therapy of childhood acute lymphoblastic leukaemia

(2015) Sophia Ingeborg Vang et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Infection-related mortality in children with acute lymphoblastic leukemia: an analysis of infectious deaths on UKALL2003

(2014) D. O'Connor et al.   BLOOD

Mercaptopurine/Methotrexate Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia

(2014) Kjeld Schmiegelow et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Differential role of thiopurine methyltransferase in the cytotoxic effects of 6-mercaptopurine and 6-thioguanine on human leukemia cells

(2013) Hazhar Karim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia

(2013) S. Radtke et al.   BLOOD

Comparison of intracellular methotrexate kinetics in red blood cells with the kinetics in other cell types

(2013) Julia Korell et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Complying with the European Clinical Trials directive while surviving the administrative pressure – An alternative approach to toxicity registration in a cancer trial

(2013) Thomas Leth Frandsen et al.   EUROPEAN JOURNAL OF CANCER

Risk group assignment differs for children and adults 1-45 yr with acute lymphoblastic leukemia treated by the NOPHO ALL-2008 protocol

(2013) Nina Toft et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia-The Influence of Thiopurine Methyltransferase Genotypes

(2013) Maria S. Ebbesen et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Population-based pediatric reference intervals for hematology, iron and transferrin

(2013) Mattias Aldrimer et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Measuring methotrexate polyglutamates in red blood cells: a new LC-MS/MS-based method

(2012) E. den Boer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Treatment-related mortality in children with acute lymphoblastic leukemia in Central America

(2011) Sumit Gupta et al.   CANCER

Liquid chromatography–tandem mass spectrometry quantification of 6-thioguanine in DNA using endogenous guanine as internal standard

(2011) Jack H. Jacobsen et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy

(2010) Tiphaine Adam de Beaumais et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Immune function in children under chemotherapy for standard risk acute lymphoblastic leukaemia - a prospective study of 20 paediatric patients

(2009) Matthias Eyrich et al.   BRITISH JOURNAL OF HAEMATOLOGY

DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma

(2009) Rikke L. Hedeland et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000

(2009) A Möricke et al.   LEUKEMIA

Pharmacogenomics of methotrexate: moving towards individualized therapy

(2009) Jacob Nersting et al.   PHARMACOGENOMICS

Immune reconstitution during maintenance therapy in children with acute lymphoblastic leukemia, relation to co-existing infection

(2008) Farha A. El-Chennawi et al.   Hematology