期刊
CANCER CELL
卷 29, 期 5, 页码 617-619出版社
CELL PRESS
DOI: 10.1016/j.ccell.2016.04.011
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资金
- Howard Hughes Medical Institute Funding Source: Medline
- NCI NIH HHS [P01 CA013106, P30 CA008748] Funding Source: Medline
In this issue of Cancer Cell, Cai et al. use genome editing to study 8p deletions in a mammary epithelial cell model and show that 8p loss of heterozygosity (LOH) attenuates the action of several genes that collectively promote cell invasion and enhance cellular sensitivity to autophagy inhibitors.
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