Bilirubin enhances the activity of ASIC channels to exacerbate neurotoxicity in neonatal hyperbilirubinemia in mice

Fear extinction requires ASIC1a-dependent regulation of hippocampal-prefrontal correlates

(2018) Qin Wang et al.   Science Advances

Bilirubin augments Ca2+ load of developing bushy neurons by targeting specific subtype of voltage-gated calcium channels

(2017) Min Liang et al.   Scientific Reports

The role of gamma-aminobutyric acid/glycinergic synaptic transmission in mediating bilirubin-induced hyperexcitation in developing auditory neurons

(2016) Xin-Lu Yin et al.   TOXICOLOGY LETTERS

Novel Potent Orthosteric Antagonist of ASIC1a Prevents NMDAR-Dependent LTP Induction

(2015) Andriy Buta et al.   JOURNAL OF MEDICINAL CHEMISTRY

Two aspects of ASIC function: Synaptic plasticity and neuronal injury

(2015) Yan Huang et al.   NEUROPHARMACOLOGY

Biophysical properties of acid-sensing ion channels (ASICs)

(2015) Stefan Gründer et al.   NEUROPHARMACOLOGY

Riluzole is a Promising Pharmacological Inhibitor of Bilirubin-Induced Excitotoxicity in the Ventral Cochlear Nucleus

(2014) Guo-Ying Han et al.   CNS Neuroscience & Therapeutics

Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damage

(2014) Federico N. Soria et al.   JOURNAL OF CLINICAL INVESTIGATION

A Bilirubin-Inducible Fluorescent Protein from Eel Muscle

(2013) Akiko Kumagai et al.   CELL

The impact of SLCO1B1 genetic polymorphisms on neonatal hyperbilirubinemia: a systematic review with meta-analysis

(2013) Jiebo Liu et al.   Jornal de Pediatria

Total lactate dehydrogenase in cerebrospinal fluid for identification of bacterial meningitis

(2013) A. Quaglia et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Molecular Mechanism of Constitutive Endocytosis of Acid-Sensing Ion Channel 1a and Its Protective Function in Acidosis-Induced Neuronal Death

(2013) W.-Z. Zeng et al.   JOURNAL OF NEUROSCIENCE

UGT1A1 gene variants and clinical risk factors modulate hyperbilirubinemia risk in newborns

(2013) P K Tiwari et al.   Journal of Perinatology

Bilirubin-Induced Neurologic Damage — Mechanisms and Management Approaches

(2013) Jon F. Watchko et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bilirubin induces auditory neuropathy in neonatal guinea pigs via auditory nerve fiber damage

(2012) Hai-Bo Ye et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining

(2012) Inês Palmela et al.   Frontiers in Cellular Neuroscience

Transport and Metabolism at Blood–Brain Interfaces and in Neural Cells: Relevance to Bilirubin-Induced Encephalopathy

(2012) Silvia Gazzin et al.   Frontiers in Pharmacology

Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death

(2011) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

Extracellular Spermine Exacerbates Ischemic Neuronal Injury through Sensitization of ASIC1a Channels to Extracellular Acidosis

(2011) B. Duan et al.   JOURNAL OF NEUROSCIENCE

Bilirubin enhances neuronal excitability by increasing glutamatergic transmission in the rat lateral superior olive

(2011) Chun-Yan Li et al.   TOXICOLOGY

Protein kinase A and C signaling induces bilirubin potentiation of GABA/glycinergic synaptic transmission in rat ventral cochlear nucleus neurons

(2010) Chun-Yan Li et al.   BRAIN RESEARCH

Metabolic Acidosis Induced by Plasmodium Falciparum Intraerythrocytic Stages Alters Blood—Brain Barrier Integrity

(2010) Sergine Zougbédé et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Type B GABA receptors contribute to the restoration of balance during vestibular compensation in mice

(2010) R. Heskin-Sweezie et al.   NEUROSCIENCE

Chronic bilirubin encephalopathy: diagnosis and outcome

(2010) Steven M. Shapiro   Seminars in Fetal & Neonatal Medicine

ASIC2a and ASIC3 Heteromultimerize to Form pH-Sensitive Channels in Mouse Cardiac Dorsal Root Ganglia Neurons

(2009) Tomonori Hattori et al.   CIRCULATION RESEARCH

Calculated free bilirubin levels and neurotoxicity

(2009) M J Daood et al.   Journal of Perinatology

Cerebrospinal fluid lactate dehydrogenase isoenzymes in children with bacterial and aseptic meningitis

(2009) Moshe Nussinovitch et al.   Translational Research

Action potential evoked transmitter release in central synapses: insights from the developing calyx of Held

(2009) Lu-Yang Wang et al.   Molecular Brain

ASIC3, a sensor of acidic and primary inflammatory pain

(2008) Emmanuel Deval et al.   EMBO JOURNAL

Acid Sensing Ion Channels in Dorsal Spinal Cord Neurons

(2008) A. Baron et al.   JOURNAL OF NEUROSCIENCE

Hyperbilirubinemia Diminishes Respiratory Drive in a Rat Pup Model

(2008) Oded Mesner et al.   PEDIATRIC RESEARCH

Identification and characterization of a subset of mouse sensory neurons that express acid-sensing ion channel 3

(2007) Y.-W. Lin et al.   NEUROSCIENCE