Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal

(2019) Mingen Liu et al.   NATURE IMMUNOLOGY

Collagen VI Contains Multiple Host Defense Peptides with Potent In Vivo Activity

(2018) Suado M. Abdillahi et al.   JOURNAL OF IMMUNOLOGY

Cancer immunotherapy using checkpoint blockade

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Structural Insights into the pH-Dependent Conformational Change and Collagen Recognition of the Human Mannose Receptor

(2018) Zhenzheng Hu et al.   STRUCTURE

Diverse Functions of Macrophages in Different Tumor Microenvironments

(2018) Ming Yang et al.   CANCER RESEARCH

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

Innate defense regulator IDR-1018 activates human mast cells through G protein-, phospholipase C-, MAPK- and NF-ĸB-sensitive pathways

(2017) Kensuke Yanashima et al.   IMMUNOLOGIC RESEARCH

Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model

(2017) Bing Catherine Wu et al.   JOURNAL OF IMMUNOLOGY

The ClusPro web server for protein–protein docking

(2017) Dima Kozakov et al.   Nature Protocols

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

M. tuberculosis -Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1

(2017) Murugesan V.S. Rajaram et al.   Cell Reports

Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake

(2017) Daniel Hargbøl Madsen et al.   Cell Reports

Translational Significance for Tumor Metastasis of Tumor-Associated Macrophages and Epithelial–Mesenchymal Transition

(2017) Wenzhe Song et al.   Frontiers in Immunology

Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment

(2017) John C. Gensel et al.   Scientific Reports

Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide

(2017) Pablo Scodeller et al.   Scientific Reports

Pan-Cancer Immunogenomic Perspective on the Tumor Microenvironment Based on PD-L1 and CD8 T-Cell Infiltration

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Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

(2016) Anna-Maria Georgoudaki et al.   Cell Reports

Recent insights into structures and functions of C-type lectins in the immune system

(2015) Kurt Drickamer et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Macrophage defense mechanisms against intracellular bacteria

(2015) Günter Weiss et al.   IMMUNOLOGICAL REVIEWS

Cell-penetrating peptides: strategies for anticancer treatment

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Autophagy-induced RelB/p52 activation mediates tumour-associated macrophage repolarisation and suppression of hepatocellular carcinoma by natural compound baicalin

(2015) H-Y Tan et al.   Cell Death & Disease

CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models

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Entering the mainstream of cancer treatment

(2014) Steven A. Rosenberg   Nature Reviews Clinical Oncology

Host defense peptides: front-line immunomodulators

(2014) Sarah C. Mansour et al.   TRENDS IN IMMUNOLOGY

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival

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Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Targeted drug delivery for cancer therapy: the other side of antibodies

(2012) Michael A Firer et al.   Journal of Hematology & Oncology

The mannose receptor

(2012) Luisa Martinez-Pomares   JOURNAL OF LEUKOCYTE BIOLOGY

Effective Adjunctive Therapy by an Innate Defense Regulatory Peptide in a Preclinical Model of Severe Malaria

(2012) A. H. Achtman et al.   Science Translational Medicine

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Mitochondrial/Cell-Surface Protein p32/gC1qR as a Molecular Target in Tumor Cells and Tumor Stroma

(2008) V. Fogal et al.   CANCER RESEARCH