标题
An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis
作者
关键词
-
出版物
SCIENCE
Volume 367, Issue 6478, Pages 652-660
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2020-02-07
DOI
10.1126/science.aay0542
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue
- (2018) Peng Zhao et al. CELL
- Mechanisms of NAFLD development and therapeutic strategies
- (2018) Scott L. Friedman et al. NATURE MEDICINE
- AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development
- (2018) Nadia Boudaba et al. EBioMedicine
- ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P
- (2018) Ju Youn Kim et al. CELL
- Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer
- (2018) Di Wu et al. NATURE
- Fighting the fatty liver
- (2017) Liam Drew NATURE
- Activation and Regulation of Caspase-6 and Its Role in Neurodegenerative Diseases
- (2015) Xiao-Jun Wang et al. Annual Review of Pharmacology and Toxicology
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Insulin inhibits AMPK activity and phosphorylates AMPK Ser485/491 through Akt in hepatocytes, myotubes and incubated rat skeletal muscle
- (2014) Rudy J. Valentine et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Caspase 3 Inactivation Protects Against Hepatic Cell Death and Ameliorates Fibrogenesis in a Diet-Induced NASH Model
- (2014) Samjhana Thapaliya et al. DIGESTIVE DISEASES AND SCIENCES
- Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance
- (2014) Tom Luedde et al. GASTROENTEROLOGY
- Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment
- (2013) Jason R. Clapper et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Caspase-6 as a novel early target in the treatment of Alzheimer's disease
- (2013) Andrea C. LeBlanc EUROPEAN JOURNAL OF NEUROSCIENCE
- Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents
- (2013) Maximilian Hatting et al. HEPATOLOGY
- An improved mouse model that rapidly develops fibrosis in non-alcoholic steatohepatitis
- (2013) Masahiko Matsumoto et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- A murine model for non-alcoholic steatohepatitis showing evidence of association between diabetes and hepatocellular carcinoma
- (2013) Masato Fujii et al. Medical Molecular Morphology
- Caspase Functions in Cell Death and Disease
- (2013) D. R. McIlwain et al. Cold Spring Harbor Perspectives in Biology
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6
- (2012) Christopher E. Heise et al. PLoS One
- Phosphorylation Regulates Assembly of the Caspase-6 Substrate-Binding Groove
- (2012) Elih M. Velázquez-Delgado et al. STRUCTURE
- Pathogenesis of Liver Fibrosis
- (2011) Virginia Hernandez-Gea et al. Annual Review of Pathology-Mechanisms of Disease
- AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function
- (2011) D. G. Hardie GENES & DEVELOPMENT
- AMP-activated protein kinase: a potential player in Alzheimer’s disease
- (2011) Antero Salminen et al. JOURNAL OF NEUROCHEMISTRY
- RIP3 mediates the embryonic lethality of caspase-8-deficient mice
- (2011) William J. Kaiser et al. NATURE
- A Quantitative Method for the Specific Assessment of Caspase-6 Activity in Cell Culture
- (2011) Dagmar E. Ehrnhoefer et al. PLoS One
- AMPK inhibition in health and disease
- (2010) Benoit Viollet et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Development of hepatic fibrosis occurs normally in AMPK-deficient mice
- (2009) Alain Da Silva Morais et al. CLINICAL SCIENCE
- Cleavage of Bid by Executioner Caspases Mediates Feed Forward Amplification of Mitochondrial Outer Membrane Permeabilization during Genotoxic Stress-induced Apoptosis in Jurkat Cells
- (2009) Shary N. Shelton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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