Potassium channel dysfunction in human neuronal models of Angelman syndrome

The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome

(2017) Jason J. Yi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysis

(2017) Michael S. Sidorov et al.   Journal of Neurodevelopmental Disorders

Ube3a loss increases excitability and blunts orientation tuning in the visual cortex of Angelman syndrome model mice

(2017) Michael L. Wallace et al.   JOURNAL OF NEUROPHYSIOLOGY

Decreased Axon Caliber Underlies Loss of Fiber Tract Integrity, Disproportional Reductions in White Matter Volume, and Microcephaly in Angelman Syndrome Model Mice

(2017) Matthew C. Judson et al.   JOURNAL OF NEUROSCIENCE

Disrupted neuronal maturation in Angelman syndrome-derived induced pluripotent stem cells

(2017) James J. Fink et al.   Nature Communications

Single molecule and multiple bond characterization of catch bond associated cytoadhesion in malaria

(2017) Ying Bena Lim et al.   Scientific Reports

Stem Cell Models of Human Brain Development

(2016) Iva Kelava et al.   Cell Stem Cell

Angelman syndrome — insights into a rare neurogenetic disorder

(2016) Karin Buiting et al.   Nature Reviews Neurology

GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility

(2016) Matthew C. Judson et al.   NEURON

g:Profiler—a web server for functional interpretation of gene lists (2016 update)

(2016) Jüri Reimand et al.   NUCLEIC ACIDS RESEARCH

Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons

(2016) F. Yi et al.   SCIENCE

Direct Induction and Functional Maturation of Forebrain GABAergic Neurons from Human Pluripotent Stem Cells

(2016) Alfred Xuyang Sun et al.   Cell Reports

Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro

(2015) P. Kirwan et al.   DEVELOPMENT

Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons

(2015) T. Kimm et al.   JOURNAL OF NEUROSCIENCE

All-Optical Interrogation of Neural Circuits

(2015) V. Emiliani et al.   JOURNAL OF NEUROSCIENCE

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis

(2015) Jiandong Sun et al.   Cell Reports

From UBE3A to Angelman syndrome: a substrate perspective

(2015) Gabrielle L. Sell et al.   Frontiers in Neuroscience

Mutation Update for UBE3A Variants in Angelman Syndrome

(2014) Bekim Sadikovic et al.   HUMAN MUTATION

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells

(2013) Yingsha Zhang et al.   NEURON

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

Xenome--a tool for classifying reads from xenograft samples

(2012) T. Conway et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Topography of Native SK Channels Revealed by Force Nanoscopy in Living Neurons

(2012) J. L. Maciaszek et al.   JOURNAL OF NEUROSCIENCE

Maternal Loss of Ube3a Produces an Excitatory/Inhibitory Imbalance through Neuron Type-Specific Synaptic Defects

(2012) Michael L. Wallace et al.   NEURON

Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability

(2012) J. R. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Molecular Mechanistic Insights into the Endothelial Receptor Mediated Cytoadherence of Plasmodium falciparum-Infected Erythrocytes

(2011) Ang Li et al.   PLoS One

Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes

(2011) Angela M. Mabb et al.   TRENDS IN NEUROSCIENCES

Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes

(2010) Stormy J. Chamberlain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Threshold Equation for Action Potential Initiation

(2010) Jonathan Platkiewicz et al.   PLoS Computational Biology

Cortical Action Potential Backpropagation Explains Spike Threshold Variability and Rapid-Onset Kinetics

(2008) Y. Yu et al.   JOURNAL OF NEUROSCIENCE

A general framework for multiple testing dependence

(2008) J. T. Leek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epilepsy in Angelman syndrome

(2007) Karine Pelc et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY