4-MeO-PCP and 3-MeO-PCMo, new dissociative drugs, produce rewarding and reinforcing effects through activation of mesolimbic dopamine pathway and alteration of accumbal CREB, deltaFosB, and BDNF levels

A new synthetic drug 5-(2-aminopropyl)indole (5-IT) induces rewarding effects and increases dopamine D1 receptor and dopamine transporter mRNA levels

(2018) Chrislean Jun Botanas et al.   BEHAVIOURAL BRAIN RESEARCH

cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia

(2018) Haitao Wang et al.   Frontiers in Molecular Neuroscience

The new designer drug buphedrone produces rewarding properties via dopamine D1 receptor activation

(2016) Ji-Hwan Oh et al.   ADDICTION BIOLOGY

Ketamine abuse potential and use disorder

(2016) Yu Liu et al.   BRAIN RESEARCH BULLETIN

Time-Dependent Serum Brain-Derived Neurotrophic Factor Decline During Methamphetamine Withdrawal

(2016) Wenwei Ren et al.   MEDICINE

The novel ketamine analog methoxetamine produces dissociative-like behavioral effects in rodents

(2016) Adam L. Halberstadt et al.   PSYCHOPHARMACOLOGY

Methamphetamine addiction: involvement of CREB and neuroinflammatory signaling pathways

(2016) Irina N. Krasnova et al.   PSYCHOPHARMACOLOGY

The qEEG Signature of Selective NMDA NR2B Negative Allosteric Modulators; A Potential Translational Biomarker for Drug Development

(2016) Deborah Keavy et al.   PLoS One

The role of serotonin in drug use and addiction

(2015) Christian P. Müller et al.   BEHAVIOURAL BRAIN RESEARCH

Brain-derived neurotrophic factor and addiction: Pathological versus therapeutic effects on drug seeking

(2015) Jacqueline M. Barker et al.   BRAIN RESEARCH

Pharmacological profile of novel psychoactive benzofurans

(2015) Anna Rickli et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Fatality Related to Two Novel Hallucinogenic Compounds: 4-Methoxyphencyclidine and 4-Hydroxy-N-methyl-N-ethyltryptamine

(2015) Iain M. McIntyre et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Reducing Ventral Tegmental Dopamine D2 Receptor Expression Selectively Boosts Incentive Motivation

(2015) Johannes W de Jong et al.   NEUROPSYCHOPHARMACOLOGY

Methoxetamine, a ketamine derivative, produced conditioned place preference and was self-administered by rats: Evidence of its abuse potential

(2015) Chrislean Jun Botanas et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Repeated ketamine administration alters N-methyl-d-aspartic acid receptor subunit gene expression: Implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans

(2014) Ke Xu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Novel psychoactive substance intoxication resulting in attempted murder

(2014) Richard Stevenson et al.   Journal of Forensic and Legal Medicine

Preparation and analytical characterization of 1-(1-phenylcyclohexyl)piperidine (PCP) and 1-(1-phenylcyclohexyl)pyrrolidine (PCPy) analogues

(2013) Jason Wallach et al.   Drug Testing and Analysis

The Neurobehavioral Pharmacology of Ketamine: Implications for Drug Abuse, Addiction, and Psychiatric Disorders

(2013) K. A. Trujillo et al.   ILAR JOURNAL

A systematic review of the effects of NMDA receptor antagonists on oscillatory activity recorded in vivo

(2013) Mark J Hunt et al.   JOURNAL OF PSYCHOPHARMACOLOGY

CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat

(2013) Irina N. Krasnova et al.   NEUROBIOLOGY OF DISEASE

The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor

(2013) Bryan L. Roth et al.   PLoS One

Effects of dopamine receptor antagonists on the acquisition of ethanol-induced conditioned place preference in mice

(2013) Melanie M. Pina et al.   PSYCHOPHARMACOLOGY

Serum brain-derived neurotrophic factor levels were reduced during methamphetamine early withdrawal

(2012) Pao-Huan Chen et al.   ADDICTION BIOLOGY

Rewarding and reinforcing effects of the NMDA receptor antagonist–benzodiazepine combination, zoletil®: Difference between acute and repeated exposure

(2012) June Bryan I. de la Peña et al.   BEHAVIOURAL BRAIN RESEARCH

Mephedrone (‘bath salt’) elicits conditioned place preference and dopamine-sensitive motor activation

(2012) Renata Lisek et al.   DRUG AND ALCOHOL DEPENDENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Transcriptional Mechanisms of Drug Addiction

(2012) Eric J. Nestler   Clinical Psychopharmacology and Neuroscience

Clinical toxicology of newer recreational drugs

(2011) Simon L. Hill et al.   CLINICAL TOXICOLOGY

Acute administration of typical and atypical antipsychotics reduces EEG gamma power, but only the preclinical compound LY379268 reduces the ketamine-induced rise in gamma power

(2011) Nigel C. Jones et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

EEG delta oscillations as a correlate of basic homeostatic and motivational processes

(2011) Gennady G. Knyazev   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Drug Wanting: Behavioral Sensitization and Relapse to Drug-Seeking Behavior

(2011) J. D. Steketee et al.   PHARMACOLOGICAL REVIEWS

Methylphenidate treatment in the spontaneously hypertensive rat: influence on methylphenidate self-administration and reinstatement in comparison with Wistar rats

(2011) Ike dela Peña et al.   PSYCHOPHARMACOLOGY

Ketamine Modulates Theta and Gamma Oscillations

(2009) Maciej T. Lazarewicz et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Mechanisms of Locomotor Sensitization to Drugs of Abuse in a Two-Injection Protocol

(2009) Emmanuel Valjent et al.   NEUROPSYCHOPHARMACOLOGY

Transcriptional mechanisms of addiction: role of  FosB

(2008) E. J Nestler   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Characterization of methylphenidate self-administration and reinstatement in the rat

(2008) Leigh C. P. Botly et al.   PSYCHOPHARMACOLOGY