Synthesized β-cyclodextrin modified graphene oxide (β-CD-GO) composite for adsorption of cadmium and their toxicity profile in cervical cancer (HeLa) cell lines

In the current study, a composite material was constructed using beta-cyclodextrin/graphene oxide (beta-CD-GO) and was then applied for the purpose of eliminating cadmium (Cd) from aqueous solution. The synthesized beta-CD-GO composite material was then subjected to characterization using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The batch study was conducted for the purpose of removing Cd(II). The results of the study revealed that the beta-CD-GO composite material demonstrated a high adsorption capacity of 196 mg/g of Cd(II) a pH 7.0. Further, the adsorption of Cd(II) on the beta-CD-GO followed pseudo second-order kinetics and equilibrium adsorption data, which fitted well to the Langmuir isotherm model. The evaluation of the toxicity of the synthesized beta-CD-GO composite material was done by the examination of the cervical cancer (HeLa) cell lines. Increasing concentration of beta-CD-GO composite material (50 mu g to 200 mu g) leads to a decline in the percentage of cell viability as from 74 % to 25 %. This study has suggested that the beta-CD-GO could play an efficient and beneficial source of the adsorbent for the purpose of eliminating Cd(II) from aqueous solution.