B2 and ALU retrotransposons are self-cleaving ribozymes whose activity is enhanced by EZH2

RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2

(2019) Qi Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Host Noncoding Retrotransposons Induced by DNA Viruses: a SINE of Infection?

(2017) Jessica M. Tucker et al.   JOURNAL OF VIROLOGY

Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes

(2017) et al.   MOLECULES

Structural Insights into the Mechanism of Group II Intron Splicing

(2017) Chen Zhao et al.   TRENDS IN BIOCHEMICAL SCIENCES

Recognizing the SINEs of Infection: Regulation of Retrotransposon Expression and Modulation of Host Cell Processes

(2017) William Dunker et al.   Viruses-Basel

Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2

(2017) Yicheng Long et al.   eLife

Destabilization of B2 RNA by EZH2 Activates the Stress Response

(2016) Athanasios Zovoilis et al.   CELL

Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers

(2015) Bogumil Kaczkowski et al.   CANCER RESEARCH

Endogenous retroviruses

(2015) Alexander Hayward et al.   CURRENT BIOLOGY

Toward a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA

(2015) Chen Davidovich et al.   MOLECULAR CELL

New classes of self-cleaving ribozymes revealed by comparative genomics analysis

(2015) Zasha Weinberg et al.   Nature Chemical Biology

Regulatory Interactions between RNA and Polycomb Repressive Complex 2

(2014) Catherine Cifuentes-Rojas et al.   MOLECULAR CELL

The Intertwining of Transposable Elements and Non-Coding RNAs

(2013) Michael Hadjiargyrou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells

(2013) Syuzo Kaneko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

(2012) Valeria Tarallo et al.   CELL

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

(2011) Kezhong Zhang et al.   EMBO JOURNAL

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

(2011) Hiroki Kaneko et al.   NATURE

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

SINEs

(2011) Dmitri A. Kramerov et al.   Wiley Interdisciplinary Reviews-RNA

Alu elements: know the SINEs

(2011) Prescott Deininger   GENOME BIOLOGY

The transcript repeat element: the human Alu sequence as a component of gene networks influencing cancer

(2010) Paula Moolhuijzen et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

(2010) S. Kaneko et al.   GENES & DEVELOPMENT

Genome-wide Identification of Polycomb-Associated RNAs by RIP-seq

(2010) Jing Zhao et al.   MOLECULAR CELL

The impact of retrotransposons on human genome evolution

(2009) Richard Cordaux et al.   NATURE REVIEWS GENETICS

Widespread Occurrence of Self-Cleaving Ribozymes

(2009) C.-H. T. Webb et al.   SCIENCE

Human Alu RNA Is a Modular Transacting Repressor of mRNA Transcription during Heat Shock

(2008) Peter D. Mariner et al.   MOLECULAR CELL

A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA

(2008) Monika Martick et al.   NATURE

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE