Review
Biochemistry & Molecular Biology
Jana Stepanovska, Monika Supova, Karel Hanzalek, Antonin Broz, Roman Matejka
Summary: Bioprinting is a modern tool used to create cell scaffolds and tissue or organ carriers by mimicking tissue properties with a variety of polymers, providing a natural environment for cell development. The focus is on the use of physically crosslinked high-concentrated collagen hydrogels for bioprinting, with an emphasis on factors influencing cell viability.
Article
Biochemistry & Molecular Biology
Maximilian Jergitsch, Zoe Allu Allue-Mengual, Roman A. Perez, Miguel A. Mateos-Timoneda
Summary: This study explores the effect of different salt, sucrose, and MC concentrations on the printability of methylcellulose hydrogels. Increasing G' improves shape fidelity, while lowering tan(delta) improves shape fidelity as well. Lowering MC concentration, extrusion rate, and nozzle gauge can increase cell viability.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Matteo Pitton, Andrea Fiorati, Silvia Buscemi, Lucio Melone, Silvia Fare, Nicola Contessi Negrini
Summary: By developing multicomponent bioinks combining pectin with TEMPO-oxidized cellulose nanofibers (TOCNFs), the research optimized the printability of pectin inks, ensuring stability of the printed hydrogels and viability of cell-laden inks.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Marta Merli, Lorenzo Sardelli, Nicolo Baranzini, Annalisa Grimaldi, Emanuela Jacchetti, Manuela Teresa Raimondi, Francesco Briatico-Vangosa, Paola Petrini, Marta Tunesi
Summary: This study proposes a highly controllable method to optimize the printability of internally crosslinked polysaccharides by introducing pH as a key parameter. The results indicate that pectin-based hydrogels could be successfully applied for neural cell culture.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Zixun Wang, Yang Yang, Yunbo Gao, Zhaoxian Xu, Shulin Yang, Mingjie Jin
Summary: This study successfully developed a UV-curable bioink system based on a novel water-soluble recombinant human collagen. The bioink demonstrated good biocompatibility and printability, and supported the expression of extracellular matrix and angiogenesis-associated proteins, enhancing cell viability.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Izar Gorronogoitia, Uzuri Urtaza, Ana Zubiarrain-Laserna, Ana Alonso-Varona, Ane Miren Zaldua
Summary: Three-dimensional bioprinting combined with natural hydrogels is a promising technology for the treatment of various pathologies and tissue regeneration. This study focuses on the printability and physicochemical properties of alginate-based hydrogels and scaffolds. The results show that the microstructure of alginate has a significant impact on its printability and mechanical properties, emphasizing the importance of controlling the viscoelastic and mechanical properties for obtaining high-resolution and precise structures.
Review
Polymer Science
Yeong-Jin Choi, Honghyun Park, Dong-Heon Ha, Hui-Suk Yun, Hee-Gyeong Yi, Hyungseok Lee
Summary: This paper provides an in-depth assessment of the recently developed 3D bioprinting technology and bioinks, focusing on the latest achievements and future aspects of using 3D bioprinting for in vitro modeling.
Article
Multidisciplinary Sciences
Shangjing Xin, Kaivalya A. Deo, Jing Dai, Navaneeth Krishna Rajeeva Pandian, David Chimene, Robert M. Moebius, Abhishek Jain, Arum Han, Akhilesh K. Gaharwar, Daniel L. Alge
Summary: An in-depth investigation was conducted on the dissipation process of HMPs during printing, revealing that external resistance and internal physicochemical properties play a key role in the printing outcome. Understanding these mechanisms can help improve the printability of HMPs and enhance their use in 3D bioprinting.
Review
Engineering, Biomedical
Yanli Cai, Soon Yee Chang, Soo Wah Gan, Sha Ma, Wen Feng Lu, Ching-Chiuan Yen
Summary: This review paper focuses on the recent developments in cell-laden nanocomposite bioinks for 3D bioprinting and their effects on the properties and performance of the bioinks. The reinforcement mechanisms and interactions between cells and nano-materials are discussed, with an emphasis on bone and cartilage tissue engineering applications. The limitations and future prospects of current cell-laden nanocomposite bioinks are also addressed.
ACTA BIOMATERIALIA
(2022)
Review
Materials Science, Multidisciplinary
Yantong Huang, Xiaohong Li, Abishek Jung Poudel, Wenqi Zhang, Lin Xiao
Summary: This review summarizes the current trends in articular cartilage tissue engineering and discusses the requirements of bioinks and 3D printing for bioprinting applications. It provides an overview of bioink materials and strategies to enhance their mechanical properties. The review also outlines the future perspectives of bioink reinforcement for 3D bioprinting of articular cartilage.
APPLIED MATERIALS TODAY
(2022)
Article
Chemistry, Medicinal
Qiqi Gao, Byoung-Soo Kim, Ge Gao
Summary: Alginate hydrogel as a bioink for 3D bioprinting has advantages of low cost, good biocompatibility, and rapid ionic gelation, but faces limitations such as lack of cell adhesive moieties, erratic biodegradability, and poor printability. Various advanced material formulations and biofabrication strategies have been developed to overcome these drawbacks and enhance the applications of alginate-based bioink in tissue engineering.
Article
Chemistry, Multidisciplinary
Sarah M. Hull, Christopher D. Lindsay, Lucia G. Brunel, Daniel J. Shiwarski, Joshua W. Tashman, Julien G. Roth, David Myung, Adam W. Feinberg, Sarah C. Heilshorn
Summary: UNION bioinks represent a versatile and universal strategy for 3D bioprinting, allowing for the printing of different cell types while maintaining high cell viability and characteristic phenotypic markers. This approach expands the toolkit of customizable materials available for 3D bioprinting.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Engineering, Biomedical
Guy Decante, Joao B. Costa, Joana Silva-Correia, Maurice N. Collins, Rui L. Reis, J. Miguel Oliveira
Summary: Three-dimensional (3D) bioprinting technology has gained significant attention in biomedical engineering and clinical applications, with advancements in bioink development allowing for more precise mimicry of native tissue characteristics and support for biofunctionality.
Review
Biotechnology & Applied Microbiology
Daekeun Kim, Minseok Kim, Jongwan Lee, Jinah Jang
Summary: Multicomponent bioinks have shown great potential in 3D bioprinting of in vitro liver tissue models. By improving the mechanical properties of the printed tissue constructs and cell functionality, multicomponent bioinks can enhance cellular responses and functions in drug screening, liver disease, and liver regenerative medicine.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Engineering, Biomedical
Fatima Garcia-Villen, Amaia Guembe, Jose M. Rey, Teresa Zuniga, Sandra Ruiz-Alonso, Laura Saenz-del-Burgo, Jesus M. Izco, Jose I. Recalde, Jose Luis Pedraz
Summary: Collagen is a key protein for tissue engineering and 3D bioprinting, but it comes with challenges such as complex extraction processes and batch-to-batch reproducibility issues. This study evaluates the use of new, fibrillar type I collagen as a standardized and reproducible collagen source for 3D printing and bioprinting. The native, type I collagen demonstrated excellent performance during 3D printing and enabled cell inclusion without hindering printability.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Materials Science, Characterization & Testing
Florencia Portillo, Oxana Yashchuk, Elida Hermida
Review
Plant Sciences
Mercedes Perez-Recalde, Ignacio E. Ruiz Arias, Elida B. Hermida
Article
Green & Sustainable Science & Technology
Oxana Yashchuk, Elida B. Hermida
CLEAN-SOIL AIR WATER
(2020)
Article
Materials Science, Multidisciplinary
Marcos Bertuola, Beatriz Araoz, Ulises Gilabert, Ana Gonzalez-Wusener, Mercedes Perez-Recalde, Carlos O. Arregui, Elida B. Hermida
Summary: This study investigated the printability and rheological properties of gelatin-alginate-hyaluronic acid inks mixed with bioactive glass for 3D bioprinting. The addition of bioactive glass impacted the storage modulus and viscosity of the inks, but improved the printing fidelity and tensile modulus of the scaffolds. Furthermore, the scaffolds showed the formation of hydroxyapatite layer and supported the attachment and growth of fibroblasts, suggesting their potential for soft tissue regeneration research.
JOURNAL OF MATERIALS SCIENCE
(2021)
Article
Environmental Sciences
Daiana Nygaard, Oxana Yashchuk, Elida B. Hermida
Summary: The present study aimed to evaluate and improve fermentation conditions for the production of polyhydroxyalkanoates (PHAs) using wild type Cupriavidus necator. Glycerol, an inexpensive industrial waste, was used as the main carbon source. The results showed successful accumulation of PHB and PHBV under optimized conditions.
WASTE AND BIOMASS VALORIZATION
(2023)
Article
Multidisciplinary Sciences
Daiana Nygaard, Oxana Yashchuk, Diego G. Noseda, Beatriz Araoz, Elida B. Hermida
Summary: The study scaled up the production of PHB by wild type C. necator from shaken flasks to a stirred-tank bioreactor with optimized media and fructose as carbon source. The use of fed-batch fermentation with an exponential feeding strategy significantly increased the PHB concentration and productivity. Physicochemical and cytotoxicity analyses indicated that the produced PHB has potential biomedical applications.
Article
Multidisciplinary Sciences
Daiana Nygaard, Oxana Yashchuk, Elida B. Hermida
Article
Multidisciplinary Sciences
Elida Beatriz Hermida, Claudio Daniel Arenas
Proceedings Paper
Materials Science, Multidisciplinary
C. D. Arenas, R. de la C. Alcar, E. B. Hermida
INTERNATIONAL CONGRESS OF SCIENCE AND TECHNOLOGY OF METALLURGY AND MATERIALS, SAM - CONAMET 2014
(2015)
Meeting Abstract
Cell & Tissue Engineering
A. Gonzalez Wusener, I. E. Ruiz, C. O. Arregui, A. N. Bolgiani, E. B. Hermida
TISSUE ENGINEERING PART A
(2014)
Article
Biotechnology & Applied Microbiology
O. Yashchuk, S. S. Miyazaki, E. B. Hermida
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
(2014)
Proceedings Paper
Materials Science, Multidisciplinary
O. Yashchuk, F. S. Portillo, E. B. Hermida
11TH INTERNATIONAL CONGRESS ON METALLURGY & MATERIALS SAM/CONAMET 2011
(2012)
Proceedings Paper
Engineering, Biomedical
I. Ruiz, E. B. Hermida, A. Baldessari
8TH ARGENTINEAN BIOENGINEERING SOCIETY CONFERENCE (SABI 2011) AND 7TH CLINICAL ENGINEERING MEETING
(2011)