Long range correlations of the ion current in SV channels. Met3PbCl influence study

The long-range correlations within the current signal time series of the Beta vulgaris vacuolar membrane under the influence of organolead compound (Met(3)PbCl) are investigated. The current time series is transformed into a dwell time series. Then the rescaled range and detrended fluctuations analyses are used. It is shown that the presence of Met(3)PbCl in the solution decreases the mean value of the Hurst exponent and therefore influences the long-range correlations in ionic channel current. This observation is statistically significant. An ion channel model is built and the experimental results reconstructed and analysed.