Article
Chemistry, Multidisciplinary
Jun-Yu Li, Wei Li, Jin Liu, Jie Zhong, Renming Liu, Huanjun Chen, Xue-Hua Wang
Summary: By integrating a single quantum dot with a single gold nanorod, the strong coupling between quantum dots and plasmonic nanoparticles has been achieved, opening up a new pathway for solid-state quantum information processing. Utilizing a wedge nanogap cavity, the plasmonic electric fields were effectively confined in the nanoshell of the quantum dot, leading to the largest spectral Rabi splitting reported so far.
Article
Materials Science, Ceramics
Sanjib Mondal, Avijit Dalal, Aniruddha Mondal
Summary: Aluminum nanoparticles (NPs) were synthesized on Erbium-doped Titanium dioxide (Er:TiO2) thin films (TFs) using sol-gel and glancing angle deposition (GLAD) technique inside a thermal evaporation system. The effects of the NPs on the electrical and optical properties of the Er:TiO2 TF were analyzed. The NPs had a diameter of 13 nm and showed plasmonic resonance in the UV region. A plasmonic photodetector (PD) was fabricated using the NPs, exhibiting high photosensitivity and fast switching behaviors under UV illumination. The device showed potential as a sensitive and cost-effective UV photodetector.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Applied
Palyam Subramanyam, Bhagatram Meena, Duvvuri Suryakala, Melepurath Deepa, Challapalli Subrahmanyam
Summary: The plasmonic Bi nanoparticles supported over a g-C3N4/Bi2S3 photoanode showed a high photo-current density and superior solar to hydrogen efficiency, proving to be an alternative to noble metal based photo-electrodes for solar-water splitting reactions.
Article
Pharmacology & Pharmacy
Shabnam Yavari, Kayode Olaifa, Darya Shafiee, Reza Rasuli, Mehdi Shafiee
Summary: Microorganisms are emerging contaminants in the environment and pose significant risks to public health. Conventional disinfection methods are often ineffective and have drawbacks. This study presents a method to synthesize nanomaterials with antimicrobial properties and demonstrates their effectiveness against Escherichia coli and Candida albicans. The synthesized nanomaterials show potential for biomedical applications.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Review
Chemistry, Analytical
Hanbo Li, Xinshuang Gao, Chenqi Zhang, Yinglu Ji, Zhijian Hu, Xiaochun Wu
Summary: This review discusses the wet-chemical synthesis and self-assembly fabrication of gold-NP-based chiral nanostructures, focusing on the growth and assembly methods of chiral nanostructures and the design and synthesis of chiral nanostructures with tunable and amplified plasmonic circular dichroism responses. In addition, the review discusses the recent trends and applications in the biomedical field.
Article
Biochemistry & Molecular Biology
Jun Wang, Dongliang Liu, Shun Yuan, Bo Gao, Lin Cheng, Yu Zhang, Kaijia Chen, Aimin Chen, Lianbi Li
Summary: Plasmonic-enhanced photocatalysis using visible light is a promising strategy for pollution photodegradation. In this study, arrays of ZnO nanosheets decorated with Au nanoparticles (Au-ZnO NS) were prepared and systematically investigated for their photocatalytic degradation performance. It was found that the photodegradation efficiency increased first and then decreased with the number of photochemical reduction cycles. Electromagnetic simulations showed the nonlinear enhancement of hot electron injection and plasmonic photodegradation in the Au-ZnO NS array. The work provides mechanistic insights into plasmonic photocatalysts for utilizing visible light and represents a promising strategy for design of high-performance visible light photocatalysts.
Article
Engineering, Environmental
Tianxiang Hang, Chuanping Li, Dandan Liang, Shuoren Li, Hui Zhou, Ping Ge, Xiandong Zhu, Tianfu Liu
Summary: Metal-organic frameworks (MOFs) based materials have great potential in catalysis design, but their applications in sensitive detection are still in the early stage. In this study, a hierarchical structure of plasmon-promoted MOFs-based photoelectrochemical immunoassays is developed with improved detection performance.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Inorganic & Nuclear
Maria Stefan, Adriana Popa, Dana Toloman, Cristian Leostean, Lucian Barbu-Tudoran, Alexandra Falamas
Summary: The rapid development of industrial processes has led to surface water pollution with various organic pollutants. This paper focuses on improving the photocatalytic performance of zinc oxide (ZnO) nanoparticles by using plasmonic resonance induced by gold (Au) nanoparticles. The results show that the presence of ZnO-Au nanocomposites increases the photocatalytic degradation of Rhodamine B (RhB) and oxytetracycline (OTC) pollutants under visible light irradiation compared to ZnO NPs, thanks to the plasmonic resonance and synergetic effects of the composite nanostructures.
Article
Nanoscience & Nanotechnology
Maosong Liu, Xin Jin, Shun Li, Jean-Baptiste Billeau, Tingyu Peng, Henan Li, Long Zhao, Zuotai Zhang, Jerome P. Claverie, Luca Razzari, Jianming Zhang
Summary: The recent application of localized surface plasmon resonances (SPRs) in metallic nanoparticles has led to the construction of plasmonic nanohybrids for heterogeneous photocatalysis. By encapsulating an Ag NP core with SiO2 and TiO2 layers, and Au NPs on the outer surface, an efficient plasmonic photocatalyst, Ag@SiO2@TiO2-Au, has been designed to enhance catalytic activity. The structure unit with strong scattering and field enhancement induced by a plasmonic resonator is shown to significantly boost photocatalytic activity for high H-2 production rates under visible light.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Toru Homma, Naoki Sawada, Takuya Ishida, Tetsu Tatsuma
Summary: Chiral plasmonic nanostructures have potential applications in chiroptical materials, devices, and chiral molecule sensors. A bottom-up, self-assembling method was used to prepare arrays of these structures, which were then properly oriented and aligned. The resulting well-aligned gold-lead dioxide nanostructure array exhibits circular dichroism and can have its handedness inverted by changing the rotation direction of the irradiated circularly polarized light.
Article
Chemistry, Physical
Yuki Nakashima, Katsuaki Tanabe
Summary: The study calculates the enhancement factors of the electromagnetic field between hydrogen-absorbing transition metals and noble metals, showing large enhancements in nanogaps that can potentially be utilized for energy applications such as hydrogen storage, sensing, and nuclear fusion. The field enhancement factors are sensitive to the particle separation but not the position in the gap, indicating geometric flexibility for applications.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Optics
Jiawei Sun, Huatian Hu, Yuhao Xu, Yang Li, Hongxing Xu
Summary: In this study, the in-situ optical tuning of the nanocavity mode in the nanocube-on-mirror nanocavities was achieved by continuous laser irradiation. Through photothermal-assisted morphology changes, the plasmon resonances were shifted by deforming the surfactant covering the silver nanocube and reshaping the nanocube curvature. It was found that the alumina-encapsulated nanocube-on-mirrors constructed by surfactant-eliminated nanocubes were capable of enduring more intense irradiation. Furthermore, the factors affecting the plasmonic heating effect were systematically investigated.
LASER & PHOTONICS REVIEWS
(2022)
Article
Nanoscience & Nanotechnology
Katarzyna Kluczyk-Korch, Tomasz. J. J. Antosiewicz
Summary: In strongly coupled light matter systems, the electronic energy levels and local electromagnetic field modes are intricately linked. The hybridization of these states creates new relaxation pathways, which are particularly important for plasmon decay into hot carriers. By using first principles calculations, we investigate the impact of the coupling strength between a plasmonic resonator and a molecule on hot carrier generation. Our atomistic approach enables the capture of changes in the electronic structure of the system. We find that hot carriers preferentially occur at excitation frequencies matching the new polaritonic resonances, and their energy distribution deviates significantly from that of the non-interacting system. This suggests the existence of new plasmon decay paths due to the appearance of hybridized nanoparticle-molecule states. We also observe direct electron transfer between the plasmonic nanoparticle and the molecule. Therefore, we can conclude that strong interaction between plasmonic nanostructures and molecules allows for manipulation of the energy distribution of generated hot carriers and opens up possibilities for charge transfer in the system.
Article
Chemistry, Applied
Jin-Feng Liao, Ya-Ting Cai, Jun-Yan Li, Yong Jiang, Xu-Dong Wang, Hong-Yan Chen, Dai-Bin Kuang
Summary: The optoelectronic performance of CsPbBr3 nanocrystal is limited by charge carrier recombination and narrow light absorption range, which can be resolved through coupling with plasmonic Au nanoparticles. The CsPbBr3-Au nanocomposite exhibits excitation-wavelength dependent carrier transfer behavior, leading to improved CO2 photocatalytic reduction activity.
JOURNAL OF ENERGY CHEMISTRY
(2021)
Article
Chemistry, Physical
Po-Ting Chen, Ming-Wei Liao, Tsong-Pyng Perng
Summary: Polystyrene nanospheres were used as a template to form hexagonal close-packed Ta2O5 nanohoneycombs, and then Au nanoparticle arrays of different sizes were deposited on them to enhance surface plasmon resonance and visible-light photocatalytic hydrogen evolution. FDTD simulation showed that the 100-nm Ta2O5 nanohoneycombs with smaller Au nanoparticles exhibited more effective localized surface plasmon resonance effect. The photocatalytic hydrogen evolution results were consistent with the simulation and tests, and the concept of effective yield ratio was proposed to explain the effects of Au nanoparticle size and spacing on hydrogen evolution efficiency.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Biochemistry & Molecular Biology
Jirayu Boonyakida, Indra Memdi Khoris, Fahmida Nasrin, Enoch Y. Park
Summary: This study aimed to develop a modular display platform for protein decoration on norovirus-like particles (NoV-LPs) by combining the NoVLP scaffold with the SpyTag/SpyCatcher bioconjugation system. Results showed that adding an extension linker increased the conjugation efficiency and level of protein decoration on the NoV-LPs. This study provides a strategy for enhancing the conjugation efficiency of NoV-LP and demonstrates the platform's utility for developing vaccines or functional nanoparticles.
Article
Nanoscience & Nanotechnology
Poushali Das, Masoomeh Sherazee, Parham Khoshbakht Marvi, Syed Rahin Ahmed, Aharon Gedanken, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: In this study, a pollution-free technique was developed to fabricate a heteroatom-doped carbon dot immobilized fluorescent biopolymer composite for functional textiles. The composite exhibited excellent antioxidant and antimicrobial properties, making it suitable for medical and healthcare applications. Hospital-acquired infections pose a significant financial burden on healthcare systems worldwide.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biochemical Research Methods
Fahmida Nasrin, Indra Memdi Khoris, Ankan Dutta Chowdhury, Sjakurrizal El Muttaqein, Enoch Y. Park
Summary: To prevent viral diseases, the development of a disposable, rapid, and convenient biosensor with high sensitivity and reliability is highly desired. In this study, a practical impedimetric biosensor has been created on a disposable electrode for the detection of two mosquito-borne viruses. The biosensor fabrication involves the formation of a conductive film, physical binding of gold nanoparticles-polyaniline, and biofunctionalization. The disposable electrode has been designed to detect Chikungunya virus and Zika virus separately with a wide linear range and low detection limits.
BIOTECHNOLOGY JOURNAL
(2023)
Article
Biochemical Research Methods
Abdulhakeem Alzahrani, Tawfiq Alsulami, Ahmad Mohammad Salamatullah, Syed Rahin Ahmed
Summary: The study presents a nanohybridization technique for detecting norovirus-like particles (NLPs) with higher sensitivity and faster response. The synthesis of fluorescent carbon quantum dots and gold nanoparticles (Au NPs) was conducted, and the plasmonic properties of Au NPs were utilized to enhance the fluorescence emission of carbon dots in the presence of NLPs in human serum. The proposed strategy shows high sensitivity, specificity, and applicability for controlling future outbreaks and point-of-care devices.
JOURNAL OF BIOLOGICAL ENGINEERING
(2023)
Article
Nanoscience & Nanotechnology
Syed Rahin Ahmed, Ana Gomez Cardoso, Herlys Viltres Cobas, Poushali Das, Aicheng Chen, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: This study presents a hydrothermal synthesis method for fluorescent graphdiyne quantum dots (GDY QDs) from graphdiyne sheets and reports, for the first time, the nanozymatic activity of GDY QDs. The GDY QDs catalyze the oxidation of H2O2 through peroxidase biomimetic nature and enable detection of H2O2 and dopamine. The findings of this study have important implications for the development of carbon-based nanocrystals with enzyme-mimicking nature for analytical approaches, particularly colorimetric nanobiosensors.
ACS APPLIED NANO MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Devarajulu Gelija, Chadrasekhar Loka, Mahendra Goddati, Na-hyun Bak, Jaebeom Lee, Moon-Deock Kim
Summary: A Ag/WO3/InGaN hybrid heterostructure was successfully developed, which exhibited superior photoabsorption ability in the visible region. The improved charge carrier separation and transfer kinetics lead to enhanced overall photoelectrochemical performance.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Njemuwa Nwaji, Juyong Gwak, Mahendra Goddati, Hyojin Kang, Adewale Hammed Pasanaje, Abhishek Sharan, Nirpendra Singh, Jaebeom Lee
Summary: This study explores the integration of 3D NiCo2S4 nanospikes into a 1D Fe3C microarchitecture, resulting in Fe3C@NiCo2S4 nanospikes electrode materials with great potential for high-performance hybrid supercapacitors.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Ana Gomez Cardoso, Syed Rahin Ahmed, Zahra Keshavarz-Motamed, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: The increasing number of deaths from cardiovascular diseases is a major concern globally. Rapid and on-site monitoring of this disease is crucial for its control and prevention. Recent research has focused on using modified nanomaterials to detect cardiac biomarkers. By enhancing the stability and specificity of biosensors through novel recognition elements and more stable nanomaterials, electrochemistry has become a realistic option for point-of-care devices. This review highlights the current state of nanomaterials conjugated with biorecognition elements for electrochemical cardiovascular disease detection and discusses the potential and drawbacks of these techniques for future cardiac device development.
BIOELECTROCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Marina Ikegaya, Enoch Y. Park, Takatsugu Miyazaki
Summary: Glycoside hydrolase family 31 (GH31) contains a-glycoside hydrolases with different substrate specificities involved in various physiological functions. This study characterized two a-galactosidases, BsGH31_19 and FpGH31_19, and found that they showed high substrate specificity against a-(1?4)-linkages in a-(1?4)-galactobiose and globotriose, unlike other reported GH31 a-galactosidases PsGal31A and MYORG. Structural analyses revealed differences in amino acid residues and dimer interfaces between BsGH31_19 and FpGH31_19 compared to PsGal31A and MYORG, providing insights into the molecular diversity and evolutionary relationships of GH31 a-galactosidases and other a-galactosidase families.
Article
Biochemistry & Molecular Biology
Jaewook Lee, Ji-Heon Lee, Seung-Yeul Lee, Sin A. Park, Jae Hoon Kim, Dajeong Hwang, Kyung A. Kim, Han Sang Kim
Summary: In this study, biocompatible nanomaterials were synthesized using gallic acid (GA) and coated onto iron oxide nanoparticles (IONPs). The GA-IONPs exhibited excellent biocompatibility and antioxidant activity, effectively attenuating exosome secretion induced by H2O2-induced oxidative stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Mahendra Goddati, Huu-Quang Nguyen, Sohyun Kang, Birhanu Bayissa Gicha, Lemma Teshome Tufa, Njemuwa Nwaji, My-Chi Thi Nguyen, Juyong Gwak, Jaebeom Lee
Summary: A feasible nanoscale framework and surface engineering can enhance PEC water-splitting performance. In this article, a new magnetoplasmonic (MagPlas) Ni-doped Au@FexOy nanorods (NRs) material is introduced as a novel photoanode. The core-shell Ni/Au@FexOy MagPlas NRs with a rugged morphology increase interface charge transfer. This recent finding provides insight for effective PEC photoanodes.
Article
Materials Science, Multidisciplinary
Huu-Quang Nguyen, My-Chi Thi Nguyen, Hyojin Kang, Hongxia Chen, David Kiwic, Fabian Matter, Elena Tervoort, Markus Niederberger, Jaebeom Lee
Summary: This study demonstrates the fabrication of chiral active structures from achiral nanoscale components by controlling the handedness and absorptive characteristics of chiral materials. The self-assembly of magnetoplasmonic nanowires into chiral active superstructures is achieved through the effect of an externally applied magnetic field. This concept can be applied to the design of optically active chiral 3D superstructures for optical filters, sensing devices, and chiral photocatalysts.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Syed Rahin Ahmed, Masoomeh Sherazee, Poushali Das, Jesse Dondapati, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: Quantum dots with unconventional properties, such as borophene quantum dots (BQDs), have been synthesized and found to exhibit nanozymatic activity and antibacterial activity, in addition to their conventional fluorescence emission nature. Through an electrochemical process, the nanozymatic activity of BQDs was significantly enhanced, enabling the detection of H2O2 with exceptional sensitivity. The remarkable findings of this study have the potential to open a pathway for the future development of electroassisted nanozymatic detection methods.
ACS APPLIED NANO MATERIALS
(2023)
Review
Chemistry, Analytical
Sjaikhurrizal El Muttaqien, Indra Memdi Khoris, Sabar Pambudi, Enoch Y. Y. Park
Summary: In the past few decades, nanomaterials have been explored in the sensing research field. However, less attention has been given to their application in biosensors for pathogenic virus detection. This review focuses on 3D nanospheres, a type of nanostructured material, and their extensive use in various sensing techniques. Signal amplification strategies using different types of nanospheres are discussed, along with challenges related to toxicity and commercialization in the development of nanosphere-based biosensors.
Article
Chemistry, Physical
Masoomeh Sherazee, Syed Rahin Ahmed, Poushali Das, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: This paper reports a novel approach for the synthesis of carbon quantum dot-gold nanoparticles and demonstrates the enhancement of their catalytic activity through electrochemical means. The method enables rapid and sensitive detection in field applications and can be utilized to improve and exploit enzymatically dependent reactions.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
