期刊
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
卷 44, 期 2, 页码 196-202出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/cjn.2016.415
关键词
Neurodegeneration; Dementia; Alzheimer's; Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Parkinson Disease; vascular cognitive impairment
资金
- Ontario Brain Institute through the Government of Ontario
- Baycrest Foundation
- Bruyere Research Institute
- Centre for Addiction and Mental Health Foundation
- London Health Sciences Foundation
- McMaster University Faculty of Health Sciences
- Ottawa Brain and Mind Research Institute
- Queen's University Faculty of Health Sciences
- Providence Care (Kingston)
- Sunnybrook Health Sciences Foundation
- Thunder Bay Regional Health Sciences Centre
- University of Ottawa Faculty of Medicine
- Windsor/Essex County ALS Association
- Temerty Family Foundation
- Canadian Institutes of Health Research Frederick Banting and Charles Best Canada Graduate Scholarship
- Heart and Stroke Foundation of Canada
- L.C. Campbell Research Chair
- Canadian Partnership for Stroke Recovery
Because individuals develop dementia as a manifestation of neurodegenerative or neurovascular disorder, there is a need to develop reliable approaches to their identification. We are undertaking an observational study (Ontario Neurodegenerative Disease Research Initiative [ONDRI]) that includes genomics, neuroimaging, and assessments of cognition as well as language, speech, gait, retinal imaging, and eye tracking. Disorders studied include Alzheimer's disease, amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease, and vascular cognitive impairment. Data from ONDRI will be collected into the Brain-CODE database to facilitate correlative analysis. ONDRI will provide a repertoire of endophenotyped individuals that will be a unique, publicly available resource.
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