Article
Chemistry, Organic
Gaoyuan Ma, James W. McDaniel, Jennifer M. Murphy
Summary: This study presents a simple and widely applicable approach for F-18-fluorination of unprotected peptides, resulting in stable thioether constructs. The reagent used in this method demonstrates excellent chemoselectivity at the cysteine residue and rapid labeling of a diverse scope of peptides.
Article
Food Science & Technology
Chen Niu, Xiying Song, Yuxiang Zhang, Lu Dai, Jianping Wei, Tianli Yue, Zihan Song
Summary: In this study, antimicrobial peptides (AMPs) produced by Pediococcus acidilactici were successfully purified using silica-decorated Fe3O4 nanoparticles (SMNPs) for controlling Alicyclobacillus acidoterrestris. The AMP binding to the surface of Fe3O4 nanoparticles was confirmed by FT-IR, and the purification process showed good antimicrobial activity under different pH and temperature conditions. The proposed one-step process for the purification of antibacterial peptides using SMNPs is convenient and effective, suggesting potential applications in purifying other peptides.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Swen Humpert, Mohamed A. Omrane, Elizaveta A. Urusova, Lothar Gremer, Dieter Willbold, Heike Endepols, Raisa N. Krasikova, Bernd Neumaier, Boris D. Zlatopolskiy
Summary: This study reports the radiolabeling of thiol-containing substrates through Pd-catalyzed S-arylation using 2-[F-18]fluoro-5-iodopyridine, which is easily accessible through a minimalist radiofluorination method. The practicality of this method was confirmed through the preparation of a novel PSMA-specific PET-tracer and the labeling of various compounds.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Medicinal
Jiangling Peng, Wei Tang, Jeffrey Rawson, Lynn Miao, Nelson Gonzalez, Runkai Yin, Jiaqi Chen, Melinda Ji, Zhixuan Li, Anna Gao, Andy Z. Wu, John E. Shively, Fouad Kandeel, Junfeng Li
Summary: GPR44 has been found to play a significant role in inflammation-related diseases, but its precise mechanism is still unclear. This study successfully developed [F-18]TM-30089 as a radiotracer for GPR44 and demonstrated its promising targeting ability. This may contribute to the understanding of GPR44's mechanism and monitoring of therapeutic progress.
Article
Chemistry, Applied
Chen Ji, Shiqi Zhang, Manna Wang, Yi Huang, Zhenxia Zhao, Wei Tan, Baoyu Liu, Jinxiang Dong
Summary: A simple strategy with additional KF in the synthesis gel was developed to fabricate mesoporous KL zeolites with tunable morphology, hierarchical structure and catalytic selectivity. The morphology of the resultant KL zeolites changed by modulating the molar ratio of KF/Al2O3, and the introduction of mesopores greatly improved the selectivity of bulk products in the alkylation between phenol with tert-butyl alcohol.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Jing Zhu, Jingyi Zhang, Ruiming Lin, Benwei Fu, Chengyi Song, Wen Shang, Peng Tao, Tao Deng
Summary: The study demonstrates a rapid and scalable microwave heating-based method for preparing Ti3C2Tx MXenes, which significantly reduces synthesis time and produces nanosheets with superior performance.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Yinping Tian, Qiang Zhu, Zeyu Sun, Didi Geng, Bingyi Lin, Xiaoling Su, Jiahui He, Miao Guo, Hong Xu, Ye Zhao, Weijie Qin, Peng George Wang, Liuqing Wen, Wen Yi
Summary: This study identifies a novel O-GlcNAcylated protein and reveals its regulatory role in cell cycle progression and DNA damage response.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Organic
Timothy J. Paris, Chris Schwartz, Eric Sundall, Rachel Willand-Charnley
Summary: A rapid one-step synthesis of alpha-ketoacetals was achieved via electrophilic etherification, obtaining different yields of products using specific substrates and peroxyacetals. The method is applicable for C-O bond formation at tertiary carbons, with the alpha-OCH3 group playing a critical role in ensuring product formation.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Physics, Applied
Igor O. Akimchenko, Gleb E. Dubinenko, Sven Rutkowski, Sergei Tverdokhlebov, Alexander O. Vorobyev, Vyacheslav M. Bouznik, Evgeny N. Bolbasov
Summary: This study explores the possibility of 3D printing polymer forms with a ferroelectric crystal structure in a one-step process, utilizing a specific copolymer as filament and a commercial 3D printer for printing. Some interesting results were obtained, including the retention of ferroelectric properties and an increase in crystallinity after annealing.
APPLIED PHYSICS LETTERS
(2021)
Article
Materials Science, Composites
Huiying Zhang, Fuyou Ke, Junyan Shao, Chaosheng Wang, Huaping Wang, Ye Chen
Summary: A highly sensitive pressure sensor with a sandwich structure was developed using a double nozzle FDM printer. The sensor, consisting of high beta phase composite and conductive PVDF composite, demonstrated high sensitivity and excellent long-term stability.
COMPOSITES SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Kuei C. Tang, Monika Raj
Summary: This study presents a novel strategy for the efficient chemical modification of proteins and enhancement of mass-detection sensitivity, which can be used for protein analysis in complex mixtures.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Tanuj Puri, Michelle L. Frost, Amelia E. B. Moore, Gary J. R. Cook, Glen M. Blake
Summary: This article introduces the method of measuring bone metabolic flux (K-i) using [F-18] sodium fluoride ([F-18]NaF) positron emission tomography (PET) scans, and proposes a simplified method that estimates K-i values from static scans and venous blood samples. By reviewing different methods of measuring arterial input functions (AIF), a non-invasive method for studying bone metabolism without arterial blood sampling is provided, which shortens scan times, simplifies procedures, and reduces costs.
Article
Microbiology
Claudia Gomes, Maria J. Pons, Juana del Valle-Mendoza, Mayumi Matsuoka, Joaquim Ruiz
Summary: This study identified two immunogenic peptides from Bartonella bacilliformis, Pap31-8 and SCS-alpha-12, with the potential to differentiate between different Bartonella species. These peptides were found to be highly immunogenic and could be useful for developing serologic tools for diagnosing Carrion's disease.
Review
Chemistry, Medicinal
Lexi Gower-Fry, Travis Kronemann, Andreas Dorian, Yinglan Pu, Carolin Jaworski, Carmen Waengler, Peter Bartenstein, Leonie Beyer, Simon Lindner, Klaus Jurkschat, Bjoern Waengler, Justin J. Bailey, Ralf Schirrmacher
Summary: Incorporation of silicon fluoride acceptor (SiFA) moieties into various molecules has enhanced the generation of F-18 radiopharmaceuticals for medical imaging. The efficient isotopic exchange radiofluorination process, along with the enhanced in vivo stability of [F-18]SiFA, makes it a suitable strategy for fluorine-18 incorporation. This review emphasizes the clinical applicability of [F-18]SiFA-labeled compounds and discusses significant radiotracers currently in clinical use.
Article
Chemistry, Physical
Bing Lu, Lingxiao Lv, Xinqun Zhang, Yang Zhao, Qing Chen, Huhu Cheng, Liangti Qu
Summary: Defective carbon materials, especially graphene, have shown great potential in energy conversion and storage due to their unique properties. Traditional preparation methods are destructive and tedious, while a new high-temperature hydrothermal method presented in this work allows for the synthesis of high defect density graphene materials with superior electrocatalytic activity and high capacitance.
JOURNAL OF POWER SOURCES
(2021)
Article
Multidisciplinary Sciences
Jeffrey Collins, Christopher M. Waldmann, Christopher Drake, Roger Slavik, Noel S. Ha, Maxim Sergeev, Mark Lazari, Bin Shen, Frederick T. Chin, Melissa Moore, Saman Sadeghi, Michael E. Phelps, Jennifer M. Murphy, R. Michael van Dam
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2017)
Article
Chemistry, Inorganic & Nuclear
Philip H. Chao, Mark Lazari, Sebastian Hanet, Maruthi Kumar Narayanam, Jennifer M. Murphy, R. Michael van Dam
APPLIED RADIATION AND ISOTOPES
(2018)
Article
Chemistry, Multidisciplinary
Huimin Tao, Fang Liu, Ruxin Zeng, Zhuzhou Shao, Lufeng Zou, Yang Cao, Jennifer M. Murphy, K. N. Houk, Yong Liang
CHEMICAL COMMUNICATIONS
(2018)
Article
Chemistry, Multidisciplinary
Brian J. Levandowski, Raymond F. Gamache, Jennifer M. Murphy, K. N. Houk
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2018)
Article
Chemistry, Organic
Maruthi Kumar Narayanam, Gaoyuan Ma, Pier Alexandre Champagne, Kendall N. Houk, Jennifer M. Murphy
Article
Biochemistry & Molecular Biology
Amlan Das, Maruthi Kumar Narayanam, Santanu Paul, Pritha Mukhnerjee, Suvranil Ghosh, Debabrata Ghosh Dastidar, Subhendu Chakrabarty, Arnab Ganguli, Biswarup Basu, Mahadeb Pal, Urmi Chatterji, Sushanta K. Banerjee, Parimal Karmakar, Dalip Kumar, Gopal Chakrabarti
JOURNAL OF BIOLOGICAL CHEMISTRY
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Kirstin A. Zettlitz, Christopher M. Waldmann, Wen-Ting K. Tsai, Richard Tavare, Jeffrey Collins, Jennifer M. Murphy, Anna M. Wu
JOURNAL OF NUCLEAR MEDICINE
(2019)
Article
Biochemistry & Molecular Biology
Dipanwita Das Mukherjee, N. Maruthi Kumar, Mukund P. Tantak, Satabdi Datta, Debabrata Ghosh Dastidar, Dalip Kumar, Gopal Chakrabarti
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
(2020)
Article
Chemistry, Multidisciplinary
Raymond F. Gamache, Kirstin A. Zettlitz, Wen-Ting K. Tsai, Jeffrey Collins, Anna M. Wu, Jennifer M. Murphy
Article
Chemistry, Multidisciplinary
Maruthi Kumar Narayanam, Gaoyuan Ma, Pier Alexandre Champagne, Kendall N. Houk, Jennifer M. Murphy
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2017)
Meeting Abstract
Biochemistry & Molecular Biology
Amlan Das, Arnab Ganguli, Maruthi Kumar Narayanam, Pritha Mukherjee, Biswarup Basu, Urmi Chatterjee, Sushanta Banerjee, Parimal Karmakar, Dalip Kumar, Gopal Chakrabarti
