Subtle structural alterations in G-quadruplex DNA regulate site specificity of fluorescence light-up probes

Selective recognition of c-MYC Pu22 G-quadruplex by a fluorescent probe

(2019) Qianqian Zhai et al.   NUCLEIC ACIDS RESEARCH

Flexible Versus Rigid G-Quadruplex DNA Ligands: Synthesis of Two Series of Bis-indole Derivatives and Comparison of Their Interactions with G-Quadruplex DNA

(2018) Bagineni Prasad et al.   CHEMISTRY-A EUROPEAN JOURNAL

Design of Modular G-quadruplex Ligands

(2018) Ana Rita Duarte et al.   ChemMedChem

Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule

(2018) Chiara Marchetti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cell penetrating thiazole peptides inhibit c-MYC expression via site-specific targeting of c-MYC G-quadruplex

(2018) Debasish Dutta et al.   NUCLEIC ACIDS RESEARCH

Ligand design to acquire specificity to intended G-quadruplex structures

(2018) Sefan Asamitsu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex

(2018) David R. Calabrese et al.   Nature Communications

Resolving the Ligand-Binding Specificity in c-MYC G-Quadruplex DNA: Absolute Binding Free Energy Calculations and SPR Experiment

(2017) Nanjie Deng et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Design and Synthesis of 2,2′-Diindolylmethanes to Selectively Target Certain G-Quadruplex DNA Structures

(2016) Madeleine Livendahl et al.   CHEMISTRY-A EUROPEAN JOURNAL

Colorimetric and fluorescence detection of G-quadruplex nucleic acids with a coumarin–benzothiazole probe

(2015) Jin-wu Yan et al.   ANALYST

Myc and cell cycle control

(2015) Gabriel Bretones et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Recent Developments in G-Quadruplex Probes

(2015) Dik-Lung Ma et al.   CHEMISTRY & BIOLOGY

High-throughput sequencing of DNA G-quadruplex structures in the human genome

(2015) Vicki S Chambers et al.   NATURE BIOTECHNOLOGY

Parmbsc1: a refined force field for DNA simulations

(2015) Ivan Ivani et al.   NATURE METHODS

Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids

(2014) Jin-Wu Yan et al.   CHEMICAL COMMUNICATIONS

g_mmpbsa—A GROMACS Tool for High-Throughput MM-PBSA Calculations

(2014) Rashmi Kumari et al.   Journal of Chemical Information and Modeling

Parameterization of DFTB3/3OB for Sulfur and Phosphorus for Chemical and Biological Applications

(2014) Michael Gaus et al.   Journal of Chemical Theory and Computation

Solution Structure of a G-quadruplex Bound to the Bisquinolinium Compound Phen-DC3

(2013) Wan Jun Chung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Parametrization and Benchmark of DFTB3 for Organic Molecules

(2012) Michael Gaus et al.   Journal of Chemical Theory and Computation

Avogadro: an advanced semantic chemical editor, visualization, and analysis platform

(2012) Marcus D Hanwell et al.   Journal of Cheminformatics

Development of a high-throughput G4-FID assay for screening and evaluation of small molecules binding quadruplex nucleic acid structures

(2011) Eric Largy et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A structural analysis of G-quadruplex/ligand interactions

(2011) Shozeb M. Haider et al.   BIOCHIMIE

DFTB3: Extension of the Self-Consistent-Charge Density-Functional Tight-Binding Method (SCC-DFTB)

(2011) Michael Gaus et al.   Journal of Chemical Theory and Computation

Solution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design

(2011) Jixun Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

How long is too long? Effects of loop size on G-quadruplex stability

(2010) Aurore Guédin et al.   NUCLEIC ACIDS RESEARCH

Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions

(2009) Aleksandr V. Marenich et al.   JOURNAL OF PHYSICAL CHEMISTRY B

G-quadruplex recognition by bis-indole carboxamides

(2008) Jyotirmayee Dash et al.   CHEMICAL COMMUNICATIONS

A hitchhiker's guide to G-quadruplex ligands

(2007) David Monchaud et al.   ORGANIC & BIOMOLECULAR CHEMISTRY