Structure and assembly of calcium homeostasis modulator proteins

Software tools for automated transmission electron microscopy

(2019) Martin Schorb et al.   NATURE METHODS

CHAP: A Versatile Tool for the Structural and Functional Annotation of Ion Channel Pores

(2019) Gianni Klesse et al.   JOURNAL OF MOLECULAR BIOLOGY

Real-time cryo-electron microscopy data preprocessing with Warp

(2019) Dimitry Tegunov et al.   NATURE METHODS

Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors

(2018) Michael C. Regan et al.   NEURON

CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes

(2018) Zhongming Ma et al.   NEURON

cisTEM, user-friendly software for single-particle image processing

(2018) Timothy Grant et al.   eLife

Structure of a volume-regulated anion channel of the LRRC8 family

(2018) Dawid Deneka et al.   NATURE

Cryo-EM structures of the human volume-regulated anion channel LRRC8

(2018) Go Kasuya et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Calhm2 governs astrocytic ATP releasing in the development of depression-like behaviors

(2017) M Jun et al.   MOLECULAR PSYCHIATRY

CALHM1-Mediated ATP Release and Ciliary Beat Frequency Modulation in Nasal Epithelial Cells

(2017) Alan D. Workman et al.   Scientific Reports

Atomic structure of the innexin-6 gap junction channel determined by cryo-EM

(2016) Atsunori Oshima et al.   Nature Communications

CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice

(2016) Valérie Vingtdeux et al.   Scientific Reports

Molecular mechanism of activation-triggered subunit exchange in Ca2+/calmodulin-dependent protein kinase II

(2016) Moitrayee Bhattacharyya et al.   eLife

CALHM1 ion channel elicits amyloid-  clearance by insulin-degrading enzyme in cell lines and in vivo in the mouse brain

(2015) V. Vingtdeux et al.   JOURNAL OF CELL SCIENCE

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes

(2015) Phillip J. Stansfeld et al.   STRUCTURE

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

NMDA receptor structures reveal subunit arrangement and pore architecture

(2014) Chia-Hsueh Lee et al.   NATURE

Effect of the CALHM1 G330D and R154H Human Variants on the Control of Cytosolic Ca2+ and Aβ Levels

(2014) Valérie Vingtdeux et al.   PLoS One

Crystal structure of a heterotetrameric NMDA receptor ion channel

(2014) E. Karakas et al.   SCIENCE

Structural and Functional Similarities of Calcium Homeostasis Modulator 1 (CALHM1) Ion Channel with Connexins, Pannexins, and Innexins

(2013) Adam P. Siebert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CLHM-1 is a Functionally Conserved and Conditionally Toxic Ca2+-Permeable Ion Channel in Caenorhabditis elegans

(2013) J. E. Tanis et al.   JOURNAL OF NEUROSCIENCE

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

(2013) Akiyuki Taruno et al.   NATURE

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Improved Parameters for the Martini Coarse-Grained Protein Force Field

(2012) Djurre H. de Jong et al.   Journal of Chemical Theory and Computation

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability

(2012) Z. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of the connexin 26 gap junction channel at 3.5 Å resolution

(2009) Shoji Maeda et al.   NATURE

A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

(2008) Ute Dreses-Werringloer et al.   CELL